Wolfgang Sucrow

The occurrence of C29 sterols with different configurations at C-24 in Cucurbita Pepo as shown by 270 MHz NMR

Abstract The 270MHz NMR spectra of the major sterols of pumpkin seeds show that the configuration at C-24 of 24-ethyl-5α-cholesta-7,22,25-trien-3β-ol and 24-ethyl-5α-cholesta-7,25-dien-3β-ol is 24β F = (24 S ) whereas the α-spinasterol has the 24α F = (24 S ) configuration.

Diosgenin saponins from Dioscorea floribunda

Abstract Five spirostanol glycosides and two furostanol glycosides were isolated from Dioscorea floribunda . In addition to the IR spectra of the free glycosides and the MS of the peracetates and permethyl ethers, the most effective method for structural determination proved to be the NMR spectra of the free saponins in pyridine- d 5 .

The biosynthesis of sterols in pumpkin

Abstract Tritium labeled 3β-hydroxy-5α-stigmasta-7,24(28)Z-diene (I) was administered to pumpkin plants ( Cucurbita pepo L.) and the sterols were isolated. The specific incorporation rates were: 3β-hydroxy-5α-stigmasta-7,22t,25-triene (II) 6·7 × 10 −1 %, 3β-hydroxy-5α-stigmasta-7,25-diene (III) 4·1 × 10 −2 %, and α-spinasterol (IV) 3·4 × 10 −4 %. From this result, I is tentatively regarded as a precursor for II and III.

Enhydrazine, XXV Einige Derivate des 1-Dimethylamino-2(1H)-chinolinons/Enehydrazines, XXV Some Derivatives of 1-Dimethylamino-2(1 H)-quinolinone

Abstract Reaction of the N,N-dimethyl enehydrazines 1 a-c with acetylene carboxylates gives the 1-dimethylamino-7,8-dihydro-2,5(1H,6H)-quinolinediones 5a and 6a-c together with some by-products of the enehydrazine (2a, 3a, 4a) and 4,5,6,7-tetrahydro-1H-indol-4-one type (7a-c). Compounds 6b and 6c have been degraded to the fully aromatic 1-dimethylamino- 2(1H)-quinolinones 12 b and 12 c.

Aliphatische Flüssigkristalle, IV [1] Synthese einiger 1-(1,3-Dioxan-2- und -5-yl)piperidine / Aliphatic Liquid Crystals, IV [1] Synthesis of Some 1-(1.3-Dioxan-2- and -5-yl)Piperidines

b , 2 The preparation of the title compounds 1and 12 is described. Their configurations are deduced from the NMR spectra. trans-4-Pentyl-1-(trans-2-pentyl-1,3-dioxan-5-yl)piperidine (2) exhibits a broad smectic B phase.

Ein nematisches N-Cyclohexylpiperidin / A Nematic N-Cyclohexylpiperidine

The preparation of the nematic 4-(4-n-pentyl-1-piperidyl)cyclohexane-1-carbonitrile (1b) via the enamine 2b and the N-Cyclohexylpiperidines 5a-c is described. The nematic range of 1b was found to be 8 °C.

Enhydrazine, XXX [1]. Phenyloge Enhydrazine ohne direkte N.N-Bindung / Enehydrazines, XXX [1]. Phenylogous Enehydrazines without a Direct N,N-Bond

The phenylogous enehydrazines 3 a-c prepared from the three isomeric benzenediamines 1 a - c and dimedone (2) were treated with the acetylenic esters 4a-b. While 3 c did not react under the applied conditions, 3 a, b gave the openchained products 5 a, b, 7 a, b, and 9 and, in one case, the ringclosed N-addition product 6 as well as the C-addition products which, however, cyclized to the corresponding quinoline-2,5-diones 8 a, b and 10. In compound 11 both reaction types were realized.

Enhydrazine, XVIII Einige weitere Indazol-Derivate / Enhydrazines, XVIII1 Further Indazol Derivatives

3-(3,4-Dimethoxyphenyl)-1-methyl-1,5,6,7-tetrahydro-4H-indazol-4-one (1) is reduced to 2 a. Dehydration of 2 a gives 3 which is hydrogenated to 4 or dehydrogenated to 5. Regiospecific bromination of 1 gives the bromoketones 6 or 7, the latter is transformed into the phenol 11 a or into the indazoloquinone 13 which is brominated to 14 and converted into the aminoquinone 15.