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Dive into the research topics where Wouter E. Roorda is active.

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Featured researches published by Wouter E. Roorda.


Journal of Biomaterials Science-polymer Edition | 1994

Do hydrogels contain different classes of water

Wouter E. Roorda

In the first part of this article calorimetric studies on poly (hydroxy ethyl methacrylate) (PHEMA) are presented. In the past the irregular melting curves in this type of experiment have been interpreted as evidence for the existence of different types of water in these gels. The studies presented here demonstrate that the occurrence of a glass transition in the freezing hydrogels may be responsible for this irregular melting behavior, and that this behavior is not (necessarily) an indication for the existence of different types of water. In the second part results are shown of measurements of the mobility of water in hydrogels, made by relaxation NMR. These results indicate that very rapid interchange occurs between the water molecules, and they support the conclusion that the calorimetric data mentioned above are not indicative for the existence of different classes of water in hydrogels. These results are compared with data from other fields of science, especially from fundamental freeze drying studies, which support the alternative interpretation of the calorimetric measurements.


Archive | 1997

Directional drug delivery stent and method of use

James E. Brown; Wouter E. Roorda


Archive | 1997

Directional drug delivery stent

Terry L. Burkoth; James E. Brown; Wouter E. Roorda


Archive | 1995

Injectable drug delivery system and method

Randall G. Berggren; David J. Enscore; Susan M. Marks; James L. Osborne; Patrick S. L. Wong; Wouter E. Roorda


Archive | 1993

Viscous suspensions of controlled-release drug particles

Wouter E. Roorda; Fred Ehnow


Archive | 1998

Diffusional implantable delivery system

Wouter E. Roorda; Keith E. Dionne; James E. Brown; Jeremy C. Wright; Craig R. Davis; Steven J. Prestrelski; Stelios T. Tzannis


Archive | 1994

Bioerodible devices and compositions for diffusional release of agents

Wouter E. Roorda; Fred Ehnow; Estela Basso; Karly Wang; Sharon M. Fujita


Archive | 1993

Erosion rate modifier for use in bioerodible drug delivery devices and method of use

Wouter E. Roorda; Fred Ehnow


Archive | 1993

Additives for bioerodible polymers to regulate degradation

Wouter E. Roorda; Fred Ehnow


Archive | 1993

Polymer system containing a partially soluble compound

Wouter E. Roorda; Fred Ehnow; Susan M. Marks

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