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Xiaohe Guo

University of Science and Technology of China

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Featured researches published by Xiaohe Guo.

Synthetic Communications | 2006

Synthesis of Novel Murrapanine Analogues by Microwave Irradiation

Xiaohe Guo; Weidong Hu; Senxiang Cheng; Limin Wang; Junbiao Chang

Abstract Some new Murrapanine analogues have been synthesized via microwave irradiation by intermolecular Diels–Alder cyclization of 1‐tosyl‐3‐(3‐methyl‐1,3‐vinylallyl) indole with a dienophile such as quinone. The structure of the compounds has been characterized by 1H NMR and MS.

European Journal of Medicinal Chemistry | 2011

Synthesis of new 2′-deoxy-2′-fluoro-4′-azido nucleoside analogues as potent anti-HIV agents

Qiang Wang; Weidong Hu; Shuyang Wang; Zhenliang Pan; Le Tao; Xiaohe Guo; Keduo Qian; Chin Ho Chen; Kuo Hsiung Lee; Junbiao Chang

Bioorganic & Medicinal Chemistry Letters | 2011

Synthesis and anti-HIV-1 activity of 4-substituted-7-(2′-deoxy-2′-fluoro-4′-azido-β-d-ribofuranosyl)pyrrolo[2,3-d]pyrimidine analogues

Xiaohe Guo; Yujiang Li; Le Tao; Qiang Wang; Shuyang Wang; Weidong Hu; Zhenliang Pan; Qinghua Yang; Yanmei Cui; Zhaopeng Ge; Lihong Dong; Xuejun Yu; Haoyun An; Chuanjun Song; Junbiao Chang

Biochemical Pharmacology | 2011

FNC, a novel nucleoside analogue inhibits cell proliferation and tumor growth in a variety of human cancer cells

Qiang Wang; Xiaobing Liu; Qingduan Wang; Yan Zhang; Jinhua Jiang; Xiaohe Guo; Qingxia Fan; Liyun Zheng; Xuejun Yu; Ning Wang; Zhenliang Pan; Chuanjun Song; Wenqing Qi; Junbiao Chang

Bioorganic & Medicinal Chemistry Letters | 2010

Synthesis and anti-HCV activity of a new 2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogue

Weidong Hu; Ping’an Wang; Chuanjun Song; Zhenliang Pan; Qiang Wang; Xiaohe Guo; Xuejun Yu; Zhenhua Shen; Shuyang Wang; Junbiao Chang

Tetrahedron | 2014

Lewis acid-catalyzed tandem acylation–Nazarov cyclization for the syntheses of fused cyclopentenones

Ertong Li; Changwei Li; Jing Wang; Jinqian Wang; Lihong Dong; Xiaohe Guo; Chuanjun Song; Junbiao Chang

Bioorganic & Medicinal Chemistry | 2005

A solid-phase approach to novel purine and nucleoside analogs.

Junbiao Chang; Chunhong Dong; Xiaohe Guo; Weidong Hu; Senxiang Cheng; Qiang Wang; Rongfeng Chen

Archive | 2008

2'-fluorine-4'-substituted-nucleosides analog, preparation method and uses thereof

Junbiao Chang; Xinhong Bao; Qiang Wang; Xiaohe Guo; Wei Wang; Xiuxiang Qi

Bioorganic & Medicinal Chemistry Letters | 2004

Efficient synthesis of γ-DDB

Junbiao Chang; Xiaohe Guo; Senxiang Cheng; Ruiyun Guo; Rongfeng Chen; Kang Zhao

Journal of Pharmaceutical and Biomedical Analysis | 2014

Quantification of 2′-deoxy-2′-β-fluoro-4′-azidocytidine in rat and dog plasma using liquid chromatography-quadrupole time-of-flight and liquid chromatography-triple quadrupole mass spectrometry: Application to bioavailability and pharmacokinetic studies

Youmei Peng; Tiefeng Cheng; Lihong Dong; Yuhai Zhang; Xiaojing Chen; Jinhua Jiang; Jingmin Zhang; Xiaohe Guo; Mintong Guo; Junbiao Chang; Qingduan Wang

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