Xiaoyin Yang
Ludwig Maximilian University of Munich
Chemical Communications | 2006
Xiaoyin Yang; Paul Knochel
The reaction of protected 4,5-diiodoimidazoles with (PhMe2CCH2)2CuLi regioselectively provides 5-cuprated imidazoles, which readily react with various electrophiles furnishing functionalized imidazoles in good yields; remarkably, these resulting mono-iodoimidazoles undergo again an iodine-copper exchange reaction in the presence of sensitive functional groups, like an aldehyde or a ketone.
Chemical Communications | 2006
Xiaoyin Yang; Paul Knochel
The iodine-copper exchange reaction allows the direct preparation of various aryl, heteroaryl and alkenyl cuprates bearing a formyl group, thus allowing a direct synthesis of polyfunctional aldehydes without the need of protecting groups or an additional oxidation step.
Synthesis | 2006
Xiaoyin Yang; Paul Knochel
3-Iodoenoates are readily converted into the corresponding alkenylcopper species with complete retention of configuration of the double bond via an iodine-copper exchange reaction. Quenching reactions with various electrophiles provide highly functionalized enoates in good yields.
Organic Letters | 2003
Xiaoyin Yang; Thomas Rotter; Claudia Piazza; Paul Knochel
Organic Letters | 2004
M. Isabel Calaza; Xiaoyin Yang; and Darunee Soorukram; Paul Knochel
Organic Letters | 2004
Xiaoyin Yang; and Andreas Althammer; Paul Knochel
Organic Letters | 2006
Xiaoyin Yang; Paul Knochel
Handbook of Functionalized Organometallics: Applications in Synthesis | 2008
Paul Knochel; Xiaoyin Yang; Nina Commermann
Synlett | 2004
Xiaoyin Yang; Paul Knochel
Synthesis | 2006
Xiaoyin Yang; Paul Knochel
