Xing’ao Li

Facile fabrication of highly efficient g-C3N4/BiFeO3 nanocomposites with enhanced visible light photocatalytic activities

Graphitic carbon nitride/bismuth ferrite (g-C3N4/BiFeO3) nanocomposites with various g-C3N4 contents have been synthesized by a simple method. After the deposition-precipitation process, the novel BiFeO3 spindle-like nanoparticles with the size of ∼100 nm were homogeneously decorated on the surfaces of the C3N4 nanosheets. A possible deposition growth mechanism is proposed on the basis of experimental results. The as-prepared g-C3N4/BiFeO3 composites exhibit high efficiency for the degradation of methyl orange (MO) under visible light irradiation, which can be mainly attributed to the synergic effect between g-C3N4 and BiFeO3. The ability to tune surface and interfacial characteristics for the optimization of photophysical properties suggests that the deposition growth process may enable formation of hybrids suitable for a range of photocatalytic applications based on g-C3N4.

Anatase TiO2 Nanoparticles with Exposed {001} Facets for Efficient Dye-Sensitized Solar Cells

Anatase TiO2 nanoparticles with exposed {001} facets were synthesized from Ti powder via a sequential hydrothermal reaction process. At the first-step hydrothermal reaction, H-titanate nanowires were obtained in NaOH solution with Ti powder, and at second-step hydrothermal reaction, anatase TiO2 nanoparticles with exposed {001} facets were formed in NH4F solution. If the second-step hydrothermal reaction was carried out in pure water, the H-titanate nanowires were decomposed into random shape anatase-TiO2 nanostructures, as well as few impurity of H2Ti8O17 phase and rutile TiO2 phase. Then, the as-prepared TiO2 nanostructures synthesized in NH4F solution and pure water were applied to the photoanodes of dye-sensitized solar cells (DSSCs), which exhibited power conversion efficiency (PCE) of 7.06% (VOC of 0.756 V, JSC of 14.80 mA/cm2, FF of 0.631) and 3.47% (VOC of 0.764 V, JSC of 6.86 mA/cm2, FF of 0.662), respectively. The outstanding performance of DSSCs based on anatase TiO2 nanoparticles with exposed {001} facets was attributed to the high activity and large special surface area for excellent capacity of dye adsorption.

Preparation of Graphene/Polypyrrole Composite Film via Electrodeposition for Supercapacitors

Graphene/polypyrrole (PPy) composite film was prepared by simple electrodeposition of graphite oxide and pyrrole mixture under acid conditions. The morphology, composition, and electronic structure of the composites were characterized by using transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectrometer, X-ray diffraction, and X-ray photoelectron spectroscopy. Based on the fast redox property of PPy and high conductivity of graphene, the prepared composite film could be constructed to a supercapacitor device directly. The electrochemical performances of the supercapacitor were investigated by cyclic voltammetry, galvanostatic charge-discharge, and electrochemical impedance spectroscopy. The composites showed better electrochemical performances than the individual components. A high specific capacitance of 335 F·g-1 was obtained with the capacitance retention of 85% after 1000 cycles at a current density of 1 A·g-1 by charge-discharge analysis between 0 and +1.0 V. The enhanced specific capacitance and cycling life implied a synergistic effect of graphene and PPy.

Interface induce growth of intermediate layer for bandgap engineering insights into photoelectrochemical water splitting.

A model of interface induction for interlayer growing is proposed for bandgap engineering insights into photocatalysis. In the interface of CdS/ZnS core/shell nanorods, a lamellar solid solution intermediate with uniform thickness and high crystallinity was formed under interface induction process. Merged the novel charge carrier transfer layer, the photocurrent of the core/shell/shell nanorod (css-NR) array was significantly improved to 14.0 mA cm−2 at 0.0 V vs. SCE, nearly 8 times higher than that of the perfect CdS counterpart and incident photon to electron conversion efficiency (IPCE) values above 50% under AM 1.5G irradiation. In addition, this array photoelectrode showed excellent photocatalytic stability over 6000 s. These results suggest that the CdS/Zn1−xCdxS/ZnS css-NR array photoelectrode provides a scalable charge carrier transfer channel, as well as durability, and therefore is promising to be a large-area nanostructured CdS-based photoanodes in photoelectrochemical (PEC) water splitting system.

Umbilical cord mesenchymal stem cell transplantation in drug-induced Stevens-Johnson syndrome

2 weeks. The rash disappeared with resolution of leg swelling without medication for CMV infection. We found that CMV seroconversion was chronologically associated with development of DVT in this case. In spite of accumulating cases of DIHS with CMV reactivation and its complications, there has been no case of DVT during DIHS, suggesting that it might have been underestimated. The presence of risk factors plays a prominent role in assessing the pretest probability of DVT: acute infection, older age (>75 years), burden cancers and previous history of thrombosis. In this case, although the patient was aged, no previous history of burden cancers or thrombosis enhanced a crucial contribution of CMV to development of DVT. Two recent case–control studies proved that CMV infection was independently associated with thrombosis among a whole cohort. This may occur because of the effect of a procoagulant on endothelial cells or induction of anti-phospholipid antibody that binds to the molecules, mimicking CMV antigens. We should draw attention to development of DVT as a serious complication of DIHS in addition to well-known serious sequels by CMV reactivation, such as encephalitis, carditis, gastroenteritis and pneumonia.

Answer to ‘Toxic epidermal necrolysis with failure of re‐epithelialization. Could umbilical cord mesenchymal stem cell transplantation have a role?’

review. Burns 1996; 22: 275–278. 3 Koh MJ, Tay YK. Stevens–Johnson syndrome and toxic epidermal necrolysis in Asian children. J Am Acad Dermatol 2010; 62: 54–60. 4 Moniz P, Casal D, Mavioso C, Castro JV, Almeida MA. Stevens–Johnson syndrome and toxic epidermal necrolysis: a 15-year retrospective study. Acta Med Port 2011; 24: 59–70. 5 Del Pozzo-Magana BR, Lazo-Langner A, Carleton B, Castro-Pastrana LI, Rieder MJ. A systematic review of treatment of drug-induced Stevens– Johnson syndrome and toxic epidermal necrolysis in children. J Popul Ther Clin Pharmacol 2011; 18: e121–e133.

Structural, optical and multiferroic properties of Eu, Ba co-doped BiFeO3

Sol–gel method is a commonly used method to prepare multiferroic BiFeO3 nanoparticles. By studying the effects of Eu and Ba co-doped on the structural, magnetic and ferroelectric properties of the samples, we found some regular features on the performance of this doped material. Optical absorption spectra indicate that the doping of Eu and Ba has an effect on the energy band structure. The analysis of UV spectrum shows that the band gap of this doped material is narrowed. Moreover, magnetic hysteresis data reveals a further enhancement of magnetism in the Eu and Ba co-doped sample. And the doping of Eu into BFO can reduce the leakage current and gain good ferroelectric properties.

SAT0194 Allogenic mesenchymal stem cells transplantation alleviates clinical sjögren’s syndrome

Background Sjögren’s syndrome (SS) is a systemic autoimmune disease that is characterized by dry mouth and dry eyes. Currently, treatment of SS is difficult and challenging. Objectives To determine the safety and efficacy of allogenic mesenchymal stem cells (MSC) transplantation in SS patients. Methods Twenty-four patients with primary SS (23 females and 1 male; age from 27 to 68 years old, mean 45 years old), that were refractory to standard treatments, were enrolled. Fresh umbilical cords (UC) were obtained from informed healthy mothers after normal deliveries. UC MSC were prepared by the Stem Cell Center of Jiangsu Province, China. Allogenic UC MSC were infused intravenously (one million cells per kilogram of body weight per infusion). The clinical manifestations and laboratory parameters were compared pre- and post- MSC transplantation (MSCT), with all patients completing 12 months follow-up. Side effects were monitored all the time during and post-MSCT. Results All patients tolerated well with allogenic UC MSCT, and no adverse events occurred during or after MSC infusion. Mean SS disease activity index (SSDAI) scores of all the 24 patients decreased from 5.63±1.44 (baseline) to 4.33±1.79 at 1 month, 4.08±1.44 at 3 months, 3.46±1.18 at 6 months, and 3.08±1.21 at 12 months after MSCT (all P<0.05). Global assessment by visual analog scale (VAS) also improved 1 month after UC MSCT, and showed further ameliorations 3, 6, and 12 months later. Unstimulated salivary flow rate of all 11 patients with symptoms of xerostomia increased significantly 2 weeks after UC MSCT (1.00±0.78 ml/10 min at 2 weeks versus 0.63±0.73 ml/10min at baseline, P <0.001, n=11) and showed a 2-fold increase at 1 month (1.26±1.02, P <0.001 versus baseline, n=11). This flow rate continued to increase on subsequent follow-up. Stimulated salivary flow rate of these 11 patients also significantly increased after MSCT (P =0.008 at 2 weeks, P =0.043 at 1 month, P =0.016 at 3 months, P =0.017 at 6 months and P =0.016 at 12 months versus baseline, n=11). The determination of modified treatment emergent symptom scale (TESS) score decreased at 2 weeks visit, and was maintained at this low level on subsequent visits. Furthermore, sialogram of the parotid gland and its excretory function were analyzed by the same radiologist and rheumatologist. Punctate sialectasias in the parotid gland slightly declined, dilation of main duct was improved 1 year after UC MSCT, and excretory function was also partially restored. Anti-SSA/Ro in serum decreased from 84.76±62.19 unit/ml at baseline to 0.51±0.22 unit/ml 1 month post-MSCT (P<0.001, n=5), and anti-SSB/La in serum decreased from 146.62±83.08 unit/ml at baseline to 52.61±38.67 unit/ml 1 month post-MSCT (P<0.001, n=4). The mechanism studies showed that the frequency of Th17 cells decreased 3 months post-MSCT (P=0.01), while the percentage of regulatory T cell (Treg) increased (P=0.013). Serum levels of TGF-β increased from 15.65±1.95 pg/ml at baseline to 17.68±3.67 pg/ml 1 month post-MSCT (P=0.05, n=4), and the levels of IL-17 decreased from 39.25±3.46 pg/ml at baseline to 37.52±0.66 1 month post-MSCT (P=0.048, n=4). Conclusions Allogenic UC MSCT is safe and results in amelioration of disease activity. These data provide a foundation for conducting allogenic UC MSCT for SS patients. Disclosure of Interest None Declared

First principle investigations of the Pbnm phase BiFeO3, BiFe0.875Mn0.125O3 and Bi0.875X0.125Fe0.875Mn0.125O3 (XBFM) (X = Ce, Gd, Lu)

The structural, magnetic, electronic and optical properties of Pbnm BiFeO3 (BFO), BiFe0.875Mn0.125O3 (BFM), Bi0.875X0.125Fe0.875Mn0.125O3 (XBFM) (X = Ce, Gd, Lu) have been investigated by the first...

Effects of Eu and Ca Co-Substitution for the Improvement of Multiferroic Properties of BiFeO3

Pure BiFeO3 (BFO), Ca-doped and Eu/Ca-codoped BFO nanoparticles were prepared by using a sol–gel method. The effects of Eu/Ca-codoped on the structural, magnetic and ferroelectric properties of the samples were studied. The X-ray diffraction (XRD) analysis reveals a structure transition in the codoped samples. Co-doped samples were obtained with the best ferromagnetic properties, with the largest remaining magnetization Mr = 0.20 emμ/g. The structure transition may be the main cause for the origin of improved magnetic properties, which destroys the space modulated spin structure of BFO and releases the locked magnetic. In addition, the doping of Eu into BFO can reduce the leakage current and enhance the ferroelectric properties.