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Featured researches published by Y. Gaumont.


Journal of Medicinal Chemistry | 1991

Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid.

Shu Wen Li; M. G. Nair; Donna M. Edwards; Roy L. Kisliuk; Y. Gaumont; Inderjit K. Dev; David S. Duch; Joan E. Humphreys; Gary K. Smith; Robert Ferone


Journal of Medicinal Chemistry | 1982

Synthesis and antitumor activity of 10-alkyl-10-deazaminopterins. A convenient synthesis of 10-deazaminopterin.

Joseph I. DeGraw; Vernon H. Brown; Tagawa H; Roy L. Kisliuk; Y. Gaumont; Francis M. Sirotnak


Journal of Medicinal Chemistry | 1975

Synthesis and biological activity of 10-thia-10-deaza analogs of folic acid, pteroic acid, and related compounds.

Y. H. Kim; Y. Gaumont; Roy L. Kisliuk; Mautner Hg


Journal of Medicinal Chemistry | 1980

Folate analogues altered in the C9--N10 bridge region. 14. 11-Oxahomofolic acid, a potential antitumor agent.

M. G. Nair; Colleen Saunders; Shiang-Yuan Chen; Roy L. Kisliuk; Y. Gaumont


Journal of Medicinal Chemistry | 1981

Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds.

M. G. Nair; Timothy W. Bridges; Timothy J. Henkel; Roy L. Kisliuk; Y. Gaumont; Francis M. Sirotnak


Journal of Medicinal Chemistry | 1983

Folate analogues. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid.

M. G. Nair; David C. Salter; Roy L. Kisliuk; Y. Gaumont; North G; Francis M. Sirotnak


Journal of Medicinal Chemistry | 1983

Folate analogues. 22. Synthesis and biological evaluation of two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system.

M. G. Nair; Salter Oc; Roy L. Kisliuk; Y. Gaumont; North G


Journal of Medicinal Chemistry | 1979

Phosphonate analogue of 2'-deoxy-5-fluorouridylic acid.

John A. Montgomery; Thomas Hj; Roy L. Kisliuk; Y. Gaumont


Journal of Medicinal Chemistry | 1979

Folate analogues altered in the C9-N10 bridge region: 11-thiohomofolic acid.

M. G. Nair; Shiang-Yuan Chen; Roy L. Kisliuk; Y. Gaumont; D. Strumpf


Journal of Medicinal Chemistry | 1978

Folate analogs altered in the C9-N10 bridge region: N10-tosylisohomofolic acid and N10-tosylisohomoaminopterin

M. G. Nair; P. Colleen O'Neal; Charles M. Baugh; Roy L. Kisliuk; Y. Gaumont; Michael Rodman

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M. G. Nair

University of South Alabama

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John A. Montgomery

Southern Research Institute

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Charles M. Baugh

University of South Alabama

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James R. Piper

Southern Research Institute

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