Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Yael Karov is active.

Publication


Featured researches published by Yael Karov.


Nature Genetics | 2005

Identification of hundreds of conserved and nonconserved human microRNAs

Isaac Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov; Shlomit Gilad; Omer Barad; Adi Barzilai; Paz Einat; Uri Einav; Eti Meiri; Eilon Sharon; Yael Spector; Zvi Bentwich

MicroRNAs are noncoding RNAs of ∼22 nucleotides that suppress translation of target genes by binding to their mRNA and thus have a central role in gene regulation in health and disease. To date, 222 human microRNAs have been identified, 86 by random cloning and sequencing, 43 by computational approaches and the rest as putative microRNAs homologous to microRNAs in other species. To prove our hypothesis that the total number of microRNAs may be much larger and that several have emerged only in primates, we developed an integrative approach combining bioinformatic predictions with microarray analysis and sequence-directed cloning. Here we report the use of this approach to clone and sequence 89 new human microRNAs (nearly doubling the current number of sequenced human microRNAs), 53 of which are not conserved beyond primates. These findings suggest that the total number of human microRNAs is at least 800.


Genome Research | 2004

MicroRNA expression detected by oligonucleotide microarrays: System establishment and expression profiling in human tissues

Omer Barad; Eti Meiri; Amir Avniel; Ranit Aharonov; Adi Barzilai; Isaac Bentwich; Uri Einav; Shlomit Gilad; Patrick Hurban; Yael Karov; Edward K. Lobenhofer; Eilon Sharon; Yoel M. Shiboleth; Marat Shtutman; Zvi Bentwich; Paz Einat


Archive | 2005

MicroRNAs and uses thereof

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2006

Prostate cancer-related nucleic acids

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2006

Liver cancer-related nucleic acids

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2010

Viral and viral associated mirnas and uses thereof

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2006

Lung cancer-related nucleic acids

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2005

Methods and apparatus for the detection and validation of micrornas

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2005

Micronas and uses thereof

Itzhak Bentwich; Amir Avniel; Yael Karov; Ranit Aharonov


Archive | 2007

NUCLEIC ACIDS INVOLVED IN VIRAL INFECTION

Issac Bentwich; Amir Avniel; Ranit Aharonov; Yael Karov; Yonat Shemer-Avni; Asal Levy

Collaboration


Dive into the Yael Karov's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Eilon Sharon

Weizmann Institute of Science

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge