Yakup Turkel

Personality profile in patients with polycystic ovary syndrome

Abstract Aim: To investigate the personality traits of patients with polycystic ovary syndrome (PCOS). Methods: Forty-nine patients with PCOS and 34 healthy controls were enrolled in the study. Psychometric evaluation was made with the Minnesota Multiphasic Personality Inventory. Additionally, Short Form-36 (SF-36) and Hospital Anxiety and Depression Scale (HADS) were also performed. Results: Polycystic ovary syndrome patients had significantly higher absolute and clinical elevation scores on depression, hysteria, psychasthenia and hypomania compared with the controls. Patients with PCOS had lower SF-36 physical and mental health summary scores and higher HADS anxiety and depression subscale scores. Conclusion: Polycystic ovary syndrome patients seem to have depressive, hysterical, psychasthenic and hypomanic personality traits.

Psychological Characteristics of Patients with Asthma.

Psychological distress of patients with asthma may be reduced when they learned to live with their illness. Asthma can change the psychological and personality characteristics. We aim to investigate the psychological and personality characteristics of patients with asthma using MMPI (Minnesota Multiphasic Personality Inventory).

Factors Influencing Cognitive Function in Subjects With COPD

BACKGROUND: The aim of this study was to assess the association between cognitive function and age, pulmonary function, comorbidity index, and the 6-min walk distance in subjects with COPD as well as to compare the Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in terms of their ability to identify cognitive dysfunction in subjects with COPD. METHODS: A total of 52 individuals with stable COPD were included in this study. Cognitive function was assessed using MMSE and MoCA. Age, body mass index, the Modified Cumulative Illness Rating Scale, 6-min walk distance, arterial blood gases, and pulmonary function tests were assessed and recorded. RESULTS: The range and SD of scores in subjects with COPD were larger with MoCA than with MMSE. MMSE and MoCA scores are associated with 6-min walk distance and comorbidity index in subjects with COPD. General cognitive function measured by MoCA was negatively correlated with the comorbidity index but was positively associated with 6-min walk distance in subjects with COPD after controlling for possible confounding factors in the multivariate model. However, general cognitive function measured by MMSE was not correlated with the comorbidity index and 6-min walk distance in subjects with COPD, after controlling for possible confounding factors in the multivariate model. CONCLUSIONS: MoCA may be a more reliable screening test than MMSE in detecting cognitive impairment in subjects with COPD. The addition of cognitive tests on assessment of subjects with COPD can provide further benefit.

Autonomic dysfunction in patients with polycystic ovary syndrome

OBJECTIVE To assess the autonomic system in patients with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS Thirty-seven adult patients with PCOS and 33 healthy controls were enrolled in the study. The electrophysiological assessments of the autonomic nervous system function were performed using sympathetic skin response and R-R interval variation tests. RESULTS The mean latency of sympathetic skin response in PCOS patients was significantly delayed compared with the controls (p = 0.001). The mean amplitude of sympathetic skin response was significantly lower in comparison with the controls (p = 0.01). Mean R-R interval variation during deep breathing was also significantly delayed (p = 0.04). CONCLUSION There are parasympathetic dysfunction and sympathetic dysfunction in patients with PCOS. This may be easily demonstrated with sympathetic skin response and R-R interval variation tests.

Fahr Syndrome Unknown Complication: Overactive Bladder

A 38-year-old male patient was admitted to our outpatient department because of frequency and urgency incontinence. During evaluation it was detected that the patient was suffering from frequency which was progressive for one year, feeling of incontinence, and urgency incontinence. There was no urologic pathology detected in patients medical and family history. Neurologic consultation was requested due to his history of boredom, reluctance to do business, balance disorders, and recession for about 3 years. Brain computerized tomography (CT) scan revealed that amorphous calcifications were detected in the bilaterally centrum semiovale, basal ganglia, capsula interna, thalami, mesencephalon, pons and bulbus, and the bilateral cerebellar hemispheres. We have detected spontaneous neurogenic detrusor overactivity without sphincter dyssynergia after evaluating the voiding diary, cystometry, and pressure flow study. We consider the detrusor overactivity which occurred one year after the start of the neurological symptoms as the suprapontine inhibition and damage in the axonal pathways in the Fahr syndrome.

The evaluation of temperament and quality of life in patients with polycystic ovary syndrome

Abstract Aims: To evaluate the temperament and quality of life (QoL) of patients with PCOS. Materials and methods: Fifty-three adult patients with PCOS and 38 healthy controls were enrolled in the study. Demographic characteristics including age, education and body mass index (BMI) were recorded. Affective temperaments were assessed by the temperament evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A) scale. The general health-related quality of life (HRQoL) instrument used in this study was short Form 36. Hospital anxiety and depression scale (HADS) were also performed. Results: The patients with PCOS had significantly higher rates of depressive, anxious and hyperthymic scores compared to controls. The PCOS patients had significantly lower mean SF-36 health summary scores. Conclusions: TEMPS-A seems to be an easy and reliable test to evaluate temperament in PCOS patients.

Validity and Reliability of Turkish Translation of Neuropathic Pain Impact on Quality‐of‐Life (NePIQoL) Questionnaire

The aim of this study was to adapt the “Neuropathic Pain Impact on Quality‐of‐Life Questionnaire” (NePIQoL) into Turkish and to test its validity and reliability in neuropathic pain patients.

Mini‑Mental State Exam versus Montreal Cognitive Assessment in Patients with Diabetic Retinopathy

BACKGROUND Mini-mental state exam (MMSE) was used several times but no study has examined cognition on the Montreal Cognitive Assessment (MoCA) in diabetes and diabetic retinopathy (DR). In this study, we compared MMSE with MoCA in patients with DR and searched for an association between the severity of DR and cognitive impairment (CI). METHODS This cross-sectional study comprised 120 consecutive patients with diabetes. Patients were divided into four groups as no DR, mild DR, severe nonproliferative DR (PDR) and PDR. Each group consisted 30 inviduals. CI was assessed using the MMSE and MoCA. RESULTS The number of subjects with a score>21 were significantly lower on the MoCA than on the MMSE between groups (all P<0.05). The mean MoCA score was significantly lower than the MMSE score (P<0.001) There was a linear association between the grade of DR and a score<21 on both tests, CONCLUSION MoCA provides more insight into the cognitive function in DR.

Attention Deficit/Hyperactivity Disorder in Adults with Multiple Sclerosis

AbstractObjectives: To determine symptoms and their effects of attentiondeficit/ hyperactivity disorder (ADHD) in adult patients with multiple sclerosis. Studies of psychiatric comorbidities in patients with multiple sclerosis (MS) have reported greater rates in MS patients than the general population. Methods: Subjects consisted of 72 relapsing remitting multiple sclerosis patients and 57 controls. Demographic characteristics including age, gender, education level, duration of disease and Expanded Disability Symptom Scale (EDSS) were recorded. ADHD symptoms were assessed by Adult Attention Deficit/HyperactivityDisorder Self-Report Scale (ASRS). Furthermore, Hospital Anxiety and Depression Scale (HADS) and Short Form-36 (SF-36) were also applied. Results: MS patients had statistically significant higher the rate of ADHD mean scores compared to controls. Patients with MS had statistically significant higher rate of clinical elevation in ASRS scores. There were 26 MS patients and 4 controls with ADHD symptoms. ASRS scores in MS patients were associated with SF- 36 mental and physical component scores and depression and anxiety scores. Conclusion: ADHD symptoms may develop in adults MS patients and are associated with lowered quality of life and increased psychosocial morbidity. In the future, more comprehensive investigations could clarify origins of ADHD symptoms in adult MS patients.

Is there a relationship between Parkinson’s disease and Chlamydia pneumoniae ?

OBJECTIVES The aim was to investigate a possible relationship between Chlamydia pneumoniae and Parkinsons disease (PD). STUDY DESIGN Serum samples obtained from a cohort of 51 patients with PD and from 37 age- and sex-matched controls were assessed for the presence of antibodies. The control group was selected from healthy people. In both groups, 5 mL of blood was taken and after centrifugation frozen at -80°C. Presence and concentration for C. pneumoniae IgM and IgG were determined by the enzyme linked immunosorbent assay (ELISA) and immunofluorescence (IFA), using C. pneumoniae IgG and IgM kit (Euroimmun, Germany). RESULTS Chlamydia pneumoniae IgG was positive in 50 (98%) patients in ELISA study. C. pneumoniae IgG was positive in 34 (92%) control subjects in ELISA study. C. pneumoniae IgG positivity in patients was slightly higher, but the difference did not reach statistical significance (P = 0.17). No statistically significant difference was found between the patient and the control groups in IFA study (P ≥ 0.5). C. pneumoniae IgM results (both ELISA and IFA study) was negative in the both PD group and control group.