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Dive into the research topics where Yasumasa Hamada is active.

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Featured researches published by Yasumasa Hamada.


Organic Letters | 2010

Catalytic Asymmetric Total Synthesis of Tangutorine

Tetsuhiro Nemoto; Eri Yamamoto; Robert Franzén; Takashi Fukuyama; Riliga Wu; Toshihiko Fukamachi; Hiroshi Kobayashi; Yasumasa Hamada

The first enantioselective total synthesis of tangutorine has been achieved, wherein a Pd-catalyzed asymmetric allylic amination using a chiral diaminophosphine oxide (DIAPHOX) preligand was the key step.


Heterocycles | 2008

Palladium-catalyzed asymmetric intramolecular metallo-ene reaction using monodentate phosphines, 9-PBN and 9-NapBN

Osamu Hara; Hiroshi Fujino; Kazuishi Makino; Yasumasa Hamada

The palladium-catalyzed asymmetric intramolecular metallo-ene reaction of the type I substrate using 9-PBN and 9-NapBN smoothly takes place in the presence of B(OAc) 3 and/or NaBF 4 at room temperature to afford the products with up to 51%ee, the best value in this area.


Organic Letters | 2007

Pd-Catalyzed Asymmetric Allylic Amination of Morita−Baylis−Hillman Adduct Derivatives Using Chiral Diaminophosphine Oxides: DIAPHOXs

Tetsuhiro Nemoto; Takashi Fukuyama; Eri Yamamoto; Shinji Tamura; Tomoaki Fukuda; Takayoshi Matsumoto; Yuichi Akimoto; Yasumasa Hamada


Tetrahedron Letters | 2006

Efficient synthesis of 3-substituted 2,3-dihydroquinolin-4-ones using a one-pot sequential multi-catalytic process : Pd-catalyzed allylic amination-thiazolium salt-catalyzed Stetter reaction cascade

Tetsuhiro Nemoto; Tomoaki Fukuda; Yasumasa Hamada


Tetrahedron | 2008

Enantioselective synthesis of martinelline chiral core and its diastereomer using asymmetric tandem Michael–aldol reaction

Yayoi Yoshitomi; Hiromi Arai; Kazuishi Makino; Yasumasa Hamada


Tetrahedron Letters | 2007

Ir-catalyzed asymmetric allylic alkylation using chiral diaminophosphine oxides : DIAPHOXs. Formal enantioselective synthesis of (-)-paroxetine

Tetsuhiro Nemoto; Tatsurou Sakamoto; Takashi Fukuyama; Yasumasa Hamada


Tetrahedron Letters | 2006

Ir-catalyzed asymmetric allylic amination using chiral diaminophosphine oxides

Tetsuhiro Nemoto; Tatsurou Sakamoto; Takayoshi Matsumoto; Yasumasa Hamada


Organic Letters | 2007

Organocatalytic synthesis of (2S,3R)-3-hydroxy-3-methyl-proline (OHMePro), a component of polyoxypeptins, and relatives using OHMePro itself as a catalyst.

Yayoi Yoshitomi; Kazuishi Makino; Yasumasa Hamada


Tetrahedron | 2007

Synthesis of 2,6-dimethyl-9-aryl-9-phosphabicyclo[3.3.1]nonanes: their application to asymmetric synthesis of chiral tetrahydroquinolines and relatives

Osamu Hara; Tomoaki Koshizawa; Kazuishi Makino; Iyo Kunimune; Atsushi Namiki; Yasumasa Hamada


Advanced Synthesis & Catalysis | 2009

Palladium‐Catalyzed Asymmetric Allylic Alkylation of 2,3‐Allenyl Acetates Using a Chiral Diaminophosphine Oxide

Tetsuhiro Nemoto; Mutsumi Kanematsu; Shinji Tamura; Yasumasa Hamada

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