Yasuo Sutani
Kansai Medical University
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Featured researches published by Yasuo Sutani.
American Journal of Cardiology | 2010
Takeshi Senoo; Masayuki Motohiro; Hiroshi Kamihata; Satoshi Yamamoto; Tsuyoshi Isono; Kenichi Manabe; Takao Sakuma; Susumu Yoshida; Yasuo Sutani; Toshiji Iwasaka
Contrast-induced nephropathy (CIN) is associated with significantly increased morbidity and mortality after coronary angiography and percutaneous coronary intervention (PCI). The aim of the present study was to assess the clinical features and in-hospital outcomes of CIN after emergency PCI. The serum creatinine (SCr) concentration was measured from days 0 to 30 in 338 consecutive patients with acute coronary syndrome undergoing emergency PCI. CIN was defined as an increase in SCr of >25% or >0.5 mg/dl within 2 days after PCI. Overall, 94 patients (28%) developed CIN. The mean SCr on admission was not significantly different between patients with CIN and those without CIN. The CIN group had significantly greater SCr at days 1, 2, and 30 than did the no CIN group. Multivariate analysis showed female gender (odds ratio [OR] 2.38, 95% confidence interval [CI] 1.12 to 5.07, p = 0.025), a culprit lesion in the left anterior descending artery (OR 2.37, 95% CI 1.31 to 4.27, p = 0.0042), contrast agent volume >200 ml (OR 3.60, 95% CI 1.96 to 6.62, p <0.001) and end-diastolic pulmonary arterial pressure >15 mm Hg (OR 2.03, 95% CI 1.02 to 4.04, p <0.01) to all correlate independently with CIN. The in-hospital mortality rate was greater in the CIN group than in the no CIN group (9.6% vs 3.3%, respectively; p = 0.025). In conclusion, CIN is a frequent complication of emergency PCI for acute coronary syndrome and is associated with a greater mortality rate and persistent renal dysfunction.
American Journal of Cardiology | 2011
Masayuki Motohiro; Hiroshi Kamihata; Satoshi Tsujimoto; Takeshi Seno; Kenichi Manabe; Tsuyoshi Isono; Yasuo Sutani; Fumio Yuasa; Toshiji Iwasaka
Contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality rates. Although a previous study reported that pretreatment with sodium bicarbonate is more effective than sodium chloride for prophylaxis of CIN, this has not been a universal finding. We performed a prospective randomized trial to investigate whether CIN can be avoided using sodium bicarbonate. In total 155 patients with a glomerular filtration rate (GFR) <60 ml/min/1.73 m(2) who were undergoing coronary angiography were enrolled. We assigned patients to sodium chloride plus sodium bicarbonate (bicarbonate group, n = 78) or sodium chloride alone (chloride group, n = 77). Infusion of sodium bicarbonate at 1 ml/kg/hour continued from 3 hours before to 6 hours after coronary angiography. CIN was defined as a 25% increase in serum creatinine from baseline value or an absolute increase of ≥0.5 mg/dl, which appeared within 2 days of contrast. Baseline GFR was not significantly different between the 2 groups. Patients in the bicarbonate group had a higher GFR than those in the chloride group on day 2 (45.8 ± 13.4 vs 40.9 ± 14.6 ml/min/1.73 m(2), p = 0.031) and at 1 month (49.5 ± 14.7 vs 43.7 ± 15.5 ml/min/1.73 m(2), p = 0.019). CIN occurred in 10 patients (13%) in the chloride group but in only 2 patients (2.6%) in the bicarbonate group (p = 0.012). Sodium chloride plus sodium bicarbonate is more effective than sodium chloride alone for prophylaxis of CIN and can lead to retention of better long-term renal function.
American Journal of Cardiology | 2001
Masahiko Kanna; Hiroshi Nonogi; Hitoshi Sumida; Shunichi Miyazaki; Satoshi Daikoku; Isao Morii; Satoshi Yasuda; Yasuo Sutani; Takeshi Baba; Yoichi Goto
The appearance of serum troponin T (tn-T) on day 1 after acute myocardial infarction (AMI) strongly depends on coronary reperfusion. In contrast, the kinetics of tn-T release after day 1 after AMI are unaffected by the reperfusion status, and reflect the degradation of myofilaments in irreversibly damaged cells. However, it is not known whether serum tn-T levels after day 1 after AMI can be used to predict the long-term outcome. The purpose of this study was to elucidate the prognostic value of determining the tn-T level on day 3 or 4 after AMI. Serum tn-T levels on day 3 or 4 after AMI were measured in 121 patients (92 men and 29 women, mean age 65 years). Mean follow-up period was 526 days. There were 12 deaths (9 cardiac and 3 noncardiac) during the follow-up period. By Kaplan-Meier analysis, patients with tn-T levels higher than the median level (6.9 ng/ml) had a significantly higher mortality rate than those with submedian levels (p <0.01). By multivariate Cox proportional-hazards regression analysis, the serum tn-T level was an independent predictor of the long-term outcome after AMI (p <0.01). Futhermore, in patients with a first AMI, the serum tn-T level exhibited a significant negative linear correlation with left ventricular ejection fraction assessed 4 weeks after AMI (r = -0.48, p <0.001). Increased serum tn-T levels on day 3 or 4 after AMI are a powerful noninvasive predictor of poor long-term prognosis, reflecting residual left ventricular function after AMI.
Japanese Circulation Journal-english Edition | 2000
Shuichi Takagi; Shunichi Miyazaki; Takashi Fujii; Satoshi Daikoku; Yasuo Sutani; Isao Morii; Satoshi Yasuda; Yoichi Goto; Hiroshi Nonogi
Japanese Circulation Journal-english Edition | 2001
Kotoe Takenaka; Satoshi Yasuda; Shunichi Miyazaki; Takashi Kurita; Yasuo Sutani; Isao Morii; Satoshi Daikoku; Shiro Kamakura; Hiroshi Nonogi
International Journal of Cardiology | 2008
Tsuyoshi Isono; Hiroshi Kamihata; Yasuo Sutani; Masayuki Motohiro; Satoshi Yamamoto; Shiori Kyoui; Yoshiji Iharada; Kouji Kurimoto; Katsuko Hara; Hakuo Takahashi; Toshiji Iwasaka
Japanese Circulation Journal-english Edition | 2001
Sunao Kojima; Hiroshi Nonogi; Isao Morii; Hitoshi Sumida; Yasuo Sutani; Satoshi Yasuda; Satoshi Daikoku; Yoichi Goto; Shunichi Miyazaki
Circulation | 2006
Satoshi Yamamoto; Hiroshi Kamihata; Yasuo Sutani; Yuzo Akita; Hajime Otani; Toshiji Iwasaka
Journal of the American College of Cardiology | 2002
Hironori Miyoshi; Hiroshi Kamihata; Yasuo Sutani; Yo Nagahama; Koichi Yamada; Kengo Hatada; Yoshiaki Tsuka; Toshiji Iwasaka
Japanese Circulation Journal-english Edition | 2009
Takeshi Senoo; Masayuki Motohiro; Hiroshi Kamihata; Kenichi Manabe; Satoshi Yamamoto; Tsuyoshi Isono; Takao Sakuma; Susumu Yoshida; Akira Moriguchi; Hiroshi Yokoe; Satoshi Tsujimoto; Yasuo Sutani; Toshiji Iwasaka