Yasushi Mikura
Takeda Pharmaceutical Company
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Publication
Featured researches published by Yasushi Mikura.
Biochimica et Biophysica Acta | 1987
Tetsuo Hoshino; Yasushi Mikura; Hirayoshi Shimidzu; Shunji Kusumoto; Junko Kawai; Hajime Toguchi
The fluorescence intensity of a unique tryptophan 36 in human interferon-gamma was drastically decreased below pH 4 with a concomitant decrease of antiviral activity. The region of residues 32-42 of human interferon-gamma was found by calculation to have a low hydrophobicity together with a high helical hydrophobic moment, and the net electric charge of this region having an amphiphilic helical structure changed significantly near pH 4. These results suggest that the region of residues 32-42 plays an important role in exhibiting antiviral activity.
Archive | 1985
Yasushi Mikura; Kensuke Asada; Hajime Toguchi
Journal of Pharmaceutical Sciences | 1994
Toshiro Heya; Hajime Toguchi; Yasushi Mikura; Akihiro Nagai; Yasutomo Miura; Tomomichi Futo; Yoshinao Tomida; Hisayoshi Shimizu
Chemical & Pharmaceutical Bulletin | 1988
Katsumi Matsuzaki; Tetsurou Handa; Koichiro Miyajima; Yasushi Mikura; Hisayoshi Shimizu; Hajime Toguchi
Archive | 1988
Yasushi Mikura; Hisayoshi Shimizu; Hajime Toguchi; Jun Sato
Archive | 1992
Yasushi Mikura; Akihiro Nagai; Hisayoshi Shimizu
Archive | 1988
Hisayoshi Shimizu; Yasushi Mikura; Yasuo Doi
Archive | 1988
Yasushi Mikura; Hisayoshi Shimizu; Hajime Toguchi; Jun Sato
Archive | 1988
Hisayoshi Shimizu; Yasushi Mikura; Yasuo Doi
Archive | 1988
Yasushi Mikura; Hisayoshi Shimizu; Hajime Toguchi; Jun Sato
