Yayoi Nishi

B-Cell-Type Malignant Lymphoma with Placental Involvement

We present here a case of B‐cell‐type mediastinal malignant lymphoma during pregnancy complicated by placental involvement. In this case, some nodular high‐echo patterns were recognized in the placenta by ultrasonography. A cesarean section and resection of the mediastinal tumor were performed at 33 weeks and 6 days of gestation due to the deterioration of the dyspnea. A female infant weighing 1,868 g was delivered and she is now a healthy 2‐year‐old. The mother, however, died of the disease 1 month after surgery, due to progression of the tumor. The placenta showed numerous white firm nodules varying from 3 mm to 3 cm in diameter. The pathologic findings of both the mediastinal tumor and the placenta indicated primary mediastinal (thymic) B‐cell lymphoma.

A new evaluation score that uses salpingoscopy to reflect fallopian tube function in infertile women

OBJECTIVE To build an evaluation scoring system using the results of salpingoscopy, and to evaluate the relationship between this scoring system and the outcome of pregnancy. DESIGN Retrospective study. SETTING Sugiyama Clinic. INTERVENTION(S) Using salpingoscopy, we observed the tubal lumen, paying attention to the following six results: adhesions, loss of mucosal folds, rounded edges of mucosal folds, debris, foreign bodies, and abnormal vessels. PATIENT(S) From April 2008 through June 2009, 104 women in whom unexplained infertility had been diagnosed underwent salpingoscopy. The F scores were evaluated related with various clinical results or pregnancy rates. MAIN OUTCOME MEASURE(S) The F score expressed the sum of the abnormal results, and one abnormal result was given a 1-point F score. RESULTS Approximately 60% of the patients showed an F score of 0, and the percentages of patients who showed 1, 2, 3, and ≥4 points were 19.2%, 11.5%, 4.5%, and 4.5%, respectively. After evaluation, 23 patients achieved pregnancy within a year. The pregnancy rates for patients with F scores of 0 and 1 point were 30.6% and 20.0%, respectively, and the rate of patients with an F score of 0 was significantly higher than the rate of patients with high F scores (F score ≥2; 9.1%). CONCLUSION(S) The patients showing a lower F score (0 or 1) showed higher fecundity than those showing an F score of ≥2.

Prostaglandin therapy during the proliferative phase improves pregnancy rates following frozen embryo transfer in a hormone replacement cycle

To determine the efficacy of prostaglandin administration during the proliferative phase in order to improve pregnancy rates following frozen embryo transfer during a hormone replacement cycle (HRC).

Effect of sera on the adhesion of natural killer cells to the endothelium in severe pre‐eclampsia

Objective:  To investigate the effect of serum on the interaction between natural killer (NK) cells and endothelial cells in pre‐eclampsia.

Elective single cleavage-stage embryo transfer need not result in lower pregnancy rates compared to double cleavage-stage embryo transfer

Aim:  To confirm whether women who choose to have one fresh embryo transferred and one frozen‐and‐thawed embryo when needed can dramatically reduce the possibility of a multifetal pregnancy while giving themselves a better chance of achieving pregnancy.

Role of salpingoscopy in assessing the inner fallopian tubes of infertility patients with ovarian endometriomas

The aim of this study was to observe the insides of the fallopian tubes of patients with unilateral or bilateral endometriomas by using salpingoscopy and evaluate the inner cavity of the fallopian tubes according to our original scoring system.