Yen-Mou Lu

Surgical treatment of the chronic tophaceous deformity in upper extremities - the shaving technique.

BACKGROUND Tophaceous gout is frequently directly related to the duration and the severity of hyperuricaemia. Conventional surgical debridement of the tophaceous lesions carries the risk of overlying skin necrosis. Life-long urate-lowering drugs have become the mainstay of primary treatment. However, surgical intervention may be necessary when the overlying skin becomes ulcerated and wound infection develops. This has become the impetus for new surgical treatment methods with less potential for morbidity. METHODS From November 2000 to July 2006, 32 patients with chronic tophaceous deposits involving their hands or elbows were treated surgically in our hospital. In this series, a soft tissue shaver device with a mini-incision technique was used to treat upper extremity tophaceous lesions. Multiple 5-mm skin incisions were made to allow direct access to the tophaceous mass. Intra-lesion shaving was done. A tourniquet aided reduction of intraoperative blood loss. Suction and irrigation were performed simultaneously while the shaver system was operating; the chalky deposits of sodium urate were thereby removed efficiently. RESULTS No major complications were noted among these 32 patients. Using this shaver technique, each tophaceous lesion was removed in less than 15 min. Twenty-nine of these operations (80.6%) were performed for patients at the intercritical gout phase. Two patients suffered a recurrent acute attack of gouty arthritis within 12h after the operation. Symptoms were controlled by oral colchicine as well as nonsteroidal anti-inflammatory drugs (NSAID). Swelling at the operative site was usually evident for the first 10 days postoperatively, therefore posture drainage is advised. CONCLUSION The shaver technique provides another option in the surgical treatment of tophaceous lesions. It prevents poor wound healing associated with tendon or joint exposure that often occurs after conventional enucleating procedures. The tophaceous lesions can be treated surgically at the intercritical gout phase. Also, the upper extremity group has a shorter hospitalisation period when compared with our preliminary study involving treatment of tophaceous deposits in the lower extremity. The shaver technique is worthy of consideration in the treatment of upper extremity chronic tophaceous patients.

Development of a Chinese Version of the Oswestry Disability Index Version 2.1

Study Design. Cross-cultural adaptation and cross-sectional psychometric testing in a convenience sample of patients with low back pain. Objective. To translate and culturally adapt the Oswestry Disability Index version 2.1 (ODI 2.1) into a Mandarin Chinese version and to assess its reliability and validity. Summary of Background Data. The Chinese ODI 2.1 has not been developed and validated. Methods. The ODI 2.1 was translated and culturally adapted to the Chinese version. The validity of the translated Chinese version was assessed by examining the relationship between the ODI and other well-known measures. Test–retest reliability was examined in 52 of these patients, who completed a second questionnaire within 1 week. Results. Internal consistency of the ODI 2.1 was excellent with Cronbach’s &agr; = 0.903. The intraclass correlation coefficient of test–retest reliability was 0.89. The minimal detectable change was 12.8. The convergent validity of the Chinese ODI is supported by its high correlation with other physical functional status measures (Roland Morris Disability Questionnaire and SF-36 physical functioning subscale, r = 0.76 and −0.75, respectively), and moderate correlation with other measures (Visual Analogue Scale, r = 0.68) and certain SF-36 subscales (role-physical, bodily pain, and social functioning, r range: −0.49 to −0.57). As expected, the ODI was least correlated with nonfunctional measures (SF-36 mental subscale and role-emotional subscale, r = −0.25 and −0.33, respectively). Conclusion. The results of this study indicate that the Chinese version of the ODI 2.1 is a reliable and valid instrument for the measurement of functional status in patients with low back pain.

Development and validation of a muscular dystrophy-specific functional rating scale

Objective: To develop a reliable and valid new rating scale for measuring the functional impact of muscular dystrophy. Design: Prospective and longitudinal investigation. Setting: Three academic medical centres in Taiwan and the Muscular Dystrophy Association of Taiwan. Measures: The Brooke Scale, the Vignos Scale, the Barthel Index, muscular strength, contracture severity, and predicted forced vital capacity (FVC%). Methods: Scale development was in three stages. In stage I, a preliminary pool of 53 items was generated from patient interviews (n-/25), literature review, existing functional rating scales and expert opinion. In stage II, these items were administered to 85 patients with muscular dystrophy. The resulting data were analysed to construct a rating scale (the Muscular Dystrophy Functional Rating Scale, MDFRS) that encompassed four unidimensional constructs: mobility, basic activities of daily living, arm function and impairment. In stage III, the measurement properties of this rating scale were assessed in 121 muscular dystrophy patients different from those examined with the preliminary instrument. Results: Internal consistency reliability was excellent for all domains of the final 33-item scale, with values of Cronbach’s alpha ranging from 0.84 to 0.97. Intraclass correlation coefficients for test-retest and inter-rater reliability were 0.99 for all domains of the MDFRS. The MDFRS showed moderate to high correlations with a range of functional rating scales measuring similar aspects and impairment parameters (Spearman’s rho=0.65-0.91; P<0.001, each). Confirmatory factor analysis supported a unitary construct of the four-dimensional MDFRS. The MDFRS had small floor and ceiling effects in the study samples. Sensitivity to change was confirmed by large standardized response means for the MDFRS total score. Conclusions: The MDFRS is a reliable and valid disease-specific measure of functional status for patients with muscular dystrophy.

Loss of cervical endplate integrity following minimal surface preparation.

Study Design. In vitro biomechanical study. Objectives. This biomechanical study was designed to evaluate the loss of endplate integrity with incremental removal of the endplate. Summary of Background Data. The position of the anterior cervical motion preserving prosthesis is very important. Unlike interbody bone graft, where a certain amount of settling is tolerable and potentially advantageous with respect to the fusion rate, a settled total disc replacement will not function properly and may dislodge. Partial or aggressive endplate removal may be a factor resulting in subsidence of an interbody device. This study was designed to precisely examine the change of endplate strength following precise burring of the surface. Methods. Eight human cadaver cervical spines (C3–C7) were dissected and 6 locations on the endplates from each vertebra were biomechanically tested using an indentation test protocol. Pairs of locations were randomly assigned to be burred to the depth of 0 mm (intact), 1 mm, or 2 mm before the testing using a flat 3-mm end mill. Strength of the endplate was statistically analyzed to examine the effect of the depth of the burr and any regional variations. Results. Significant differences (P < 0.0001) in endplate strength was noted between the intact endplate (106 ± 86 N) and burred endplates (1 mm depth, 59 ± 49 N; 2 mm depth, 51 ± 46 N). No significant differences existed between the burr depths of 1 and 2 mm (P = 0.21). The posterior endplate was significantly stronger than the anterior endplate irrespective of depth of burr. Conclusion. There is a significant loss of endplate integrity when 1 mm of endplate (44% loss) or 2 mm of endplate (52% loss) is removed. Although the implant interface plays an important role in the magnitude of the subsidence of a device, this study in general shows that the endplate is important in terms of maximizing the strength of a construct.

Spinal infection in intravenous drug abusers.

The number of intravenous (IV) drug abusers has been increasing in recent years. They are generally younger and healthier than the typical patient with a spinal infection. Reviewing the English language literature, there are only a few articles discussing the relationship between IV drug abuse and spinal infection. We studied 21 IV drug abusers with spinal infection. All were male, 19 were in their 30s and 40s with a mean age of 44 years. The mean follow-up period was 41 months after surgical intervention. Mild and severe neurologic deficit were seen in 5 and 13 patients (Frankel Grade C in 5, Grade D in 8), respectively. The overall positive culture rate was 17 out of 21 (81%). Twelve patients were infected with Staphylococcus aureus and 3 with Pseudomonas aeruginosa. Two had Mycobacterium tuberculosis. All were treated with anterior debridement and strut bone grafting with or without posterior instrumentation, laminectomy and abscess excision, or with additional discectomy. All patients with neurologic deficit recovered to a normal status. At the most recent follow-up, all the spine segments had fused and no one complained of any recurrent back pain. There were no postoperative complications. Physicians need to be more alert to the possibility of spinal infection in IV drug abusers with back pain. In addition to Staphylococcus aureus, Pseudomonas aeruginosa and Mycobacterium tuberculosis may be seen among IV drug abusers.

Measurement precision of the disability for back pain scale-by applying Rasch analysis

BackgroundThe Oswestry Disability Index (ODI) is widely used for patients with back pain. However, few studies have examined its psychometric properties using modern measurement theory. The purpose of this study was to investigate the psychometric properties of the ODI in patients with back pain using Rasch analysis.MethodsA total of 408 patients with back pain participated in this cross-sectional study. Patients were recruited from the orthopedic, neurosurgery, rehabilitation departments and pain clinic of two hospitals. Rasch analysis was used to examine the Chinese version of ODI 2.1 for unidimensionality, item difficulty, category function, differential item functioning, and test information.ResultsThe fit statistics showed 10 items of the ODI fitted the model’s expectation as a unidimensional scale. The ODI measured the different levels of functional limitation without skewing toward the lower or higher levels of disability. No significant ceiling and floor effects and gaps among the items were found. The reliability was high and the test information curve demonstrated precise dysfunction estimation.ConclusionsOur results showed that the ODI is a unidimensional questionnaire with high reliability. The ODI can precisely estimate the level of dysfunction, and the item difficulty of the ODI matches the person ability. For clinical application, using logits scores could precisely represent the disability level, and using the item difficulty could help clinicians design progressive programs for patients with back pain.

Correlations between Quality of Life and Psychological Factors in Patients with Chronic Neck Pain

The purpose of this study was to investigate health‐related quality of life (HRQOL) and associated factors in patients with chronic neck pain (CNP). The HRQOL of patients with CNP was assessed by the Short Form‐36 questionnaire in this cross‐sectional study. To evaluate the psychological factors related to HRQOL, the Eysenck Personality Questionnaire, Chinese Health Questionnaire, and Beck Anxiety Inventory were used. The scores for the eight subscales of Short Form‐36 were all lower than the Taiwanese age‐matched normative values (p < 0.001). The two most strongly affected subscales were the role–physical subscale and the bodily pain sub‐scale; both scores were below half the score of the age‐/sex‐matched normative values. The physical components summary score, a summary measure, was moderately correlated with age (ρ = −0.43), education level (ρ = 0.37) and Beck Anxiety Inventory score (ρ = −0.36). The mental components summary score was moderately to highly correlated with the Chinese Health Questionnaire score (ρ = −0.72), the neuroticism domain of Eysenck Personality Questionnaire (ρ = −0.52) and Beck Anxiety Inventory score (ρ = −0.41). The HRQOL of patients with CNP was worse than that of normal subjects across all domains. Furthermore, patients with a neurotic personality, minor psychiatric morbidity and higher anxiety status showed poor mental health, as measured by the Short Form‐36. We found that patients with CNP had multiple physical and mental health problems in terms of. The mental health of patients with CNP was strongly associated with various psychological factors. Comprehensive assessment of the physical and mental functioning of patients with CNP can improve the management and care of these patients.

Influence of Testing Position on the Reliability of Hip Extensor Strength Measured by a Handheld Dynamometer

Hip extensors belong to an important muscle group that controls standing, walking and other functional activities. The prone position (PP) is commonly used to measure the strength of the hip extensors; however, the reliability of such measurements is poor. The aim of this study was to determine the effect of different testing positions, that is, the PP and the prone standing position (PSP), on the reliability of measurements of hip extensor strength. Intrasession reliability and interrater reliability studies were performed on 47 and 16 normal subjects, respectively. The muscle strength of the hip extensors was tested in both the PP and PSP. A handheld dynamometer and break test were used to measure the strength. Relative reliability and absolute reliability were assessed in both PP and PSP. For relative reliability, the intraclass correlation coefficient (ICC) was used to examine the level of reproducibility among measurements. Absolute reliability, the smallest real difference (SRD), was used to provide information on measurement error. The results showed that the reliability was better in PSP than in PP. For relative reliability, the values of ICCs were excellent in the intrasession reliability study, in both PP (ICC1,3 = 0.92) and PSP (ICC1,3 = 0.94). However, the interrater reliability was only excellent in PSP; the ICC2,3 were 0.92 in PSP and 0.65 in PP. For absolute reliability, the values of the SRD were much lower in PSP (29.8) than in PP (71.8), indicating that the measurement of muscle strength in PSP was more stable and had smaller measurement error than in PP. Changing the testing position from the traditional “prone” to “prone‐standing” effectively improved both the relative reliability and the absolute reliability.

Treatment for Frozen Shoulder Combined with Calcific Tendinitis of the Supraspinatus

Calcific tendinitis of the shoulder is a process that involves calcium deposition in the rotator cuff tendons. It is usually a self‐limiting process and is often chronic in nature. However, it can lead to acute pain resulting in frozen shoulder syndrome. We report 32 cases in which frozen shoulder was associated with calcific tendinitis of the supraspinatus. The aim of this study was to use arthroscopic brisement of the glenohumeral joint and make multiple punctures in the calcific spot to treat the frozen shoulder associated with calcific tendinitis of the supraspinatus. In our study, 30 patients had satisfactory results after a 2‐year follow‐up. Five patients experienced some postoperative calcium shadows, but there was also greater improvement in the range of motion and pain relief in this study compared with other reports in the literature of frozen shoulder cases.

Strength and Functional Measurement for Patients with Muscular Dystrophy

This chapter places emphasis on patients with more weakness in proximal than distal parts. The most common type of proximal muscular dystrophy is Duchenne muscular dystrophy (DMD). Due to rapid deterioration, DMD can be seen as a severe form of muscular dystrophy. Other types of proximal muscular dystrophies have a slower rate of disease progression compared to DMD, such as Beck muscular dystrophy (BMD), limb girdle muscular dystrophy (LGMD), facioscapulohumeral muscular dystrophy (FSHD) and others.