Yi Ju Tsai

An Inertial Pen With Dynamic Time Warping Recognizer for Handwriting and Gesture Recognition

This paper presents an inertial-sensor-based digital pen (inertial pen) and its associated dynamic time warping (DTW)-based recognition algorithm for handwriting and gesture recognition. Users hold the inertial pen to write numerals or English lowercase letters and make hand gestures with their preferred handheld style and speed. The inertial signals generated by hand motions are wirelessly transmitted to a computer for online recognition. The proposed DTW-based recognition algorithm includes the procedures of inertial signal acquisition, signal preprocessing, motion detection, template selection, and recognition. We integrate signals collected from an accelerometer, a gyroscope, and a magnetometer into a quaternion-based complementary filter for reducing the integral errors caused by the signal drift or intrinsic noise of the gyroscope, which might reduce the accuracy of the orientation estimation. Furthermore, we have developed a minimal intra-class to maximal inter-class based template selection method (min-max template selection method) for a DTW recognizer to obtain a superior class separation for improved recognition. Experimental results have successfully validated the effectiveness of the DTW-based recognition algorithm for online handwriting and gesture recognition using the inertial pen.

Older adults adopted more cautious gait patterns when walking in socks than barefoot

Walking barefoot or in socks is common for ambulating indoors and has been reported to be associated with increased risk of falls and related injuries in the elderly. This study sought to determine if gait patterns differed between these two conditions for young and older adults. A motion analysis system was used to record and calculate the stride characteristics and motion of the bodys center of mass (COM) of 21 young and 20 older adults. For the walking tasks, the participants walked on a smooth floor surface at their preferred speed either barefoot or in socks in a random order. The socks were commercially available and commonly used. The results demonstrated that while walking in socks, compared with walking barefoot, older adults adopted a more cautious gait pattern including decreased walking speed and shortened stride length as well as reduced COM minimal velocity during the single limb support phase. Young adults, however, did not demonstrate significant changes. These findings suggest that walking with socks might present a greater balance threat for older adults. Clinically, safety precautions about walking in socks should be considered to be given to older adults, especially those with balance deficits.

Increased shoe sole hardness results in compensatory changes in the utilized coefficient of friction during walking

Based on mechanical testing, harder soled shoes have been shown to provide less available friction than soft soled shoes. Whether or not humans adjust their utilized coefficient of friction (COFu) and gait kinematics to accommodate the decrease in available friction while wearing hard soled shoes is not known. Fifty-six young adults participated in this study. Ground reaction forces, full body kinematics, stride characteristics and subjective perception of footwear slipperiness were recorded under both hard and soft soled shoe conditions. Paired t-tests were used to identify the differences between two shoes conditions. Results indicated that the peak COFu was significantly less when wearing the hard soled shoes compared to when wearing the soft soled shoes (0.23 vs. 0.26, P<0.001). The decrease in peak COFu was the result of a decrease in the resultant shear forces at the time of peak COFu as no difference in the vertical ground reaction forces was observed. When wearing hard soled shoes, subjects demonstrated decreased total body center of mass (COM) acceleration prior to and immediately following initial contact, decreased walking velocity, shortened stride length, and reduced ankle dorsiflexion angle at initial contact. Taken together, we believe that these gait modifications represent behavioral adaptations to wearing shoes that are perceived to be more slippery.

Assessment of walkway tribometer readings in evaluating slip resistance: A gait-based approach

ABSTRACT: The purpose of this study was to assess the viability of using slip risk (as quantified during human subject walking trials) to create a reference standard against which tribometer readings could be compared. First, human subjects (N=84) were used to rank objectively the slipperiness of three different surfaces with and without a contaminant (six conditions). Second, nine tribometers were used to independently measure and rank surface slipperiness for all six conditions. The slipperiness ranking determined from the walking trials was considered the reference against which the tribometer measurements were compared. Our results revealed that only two of the nine tribometers tested (Tortus II and Mark III) met our compliance criteria by both correctly ranking all six conditions and differentiating between surfaces of differing degrees of slipperiness. These findings reinforce the need for objective criteria to ascertain which tribometers effectively evaluate floor slipperiness and a pedestrians risk of slipping.

Reaching forward: effects of a preceding task and aging

Forward reaching is an integral part of many essential daily activities. It is often performed while standing quietly or after standing up from a seated position. This study sought to determine how a preceding balance task and aging would affect the task performance and movement strategy. Twenty-two healthy young and 20 older adults participated in this study and performed forward reaching under two task conditions. In forward reach (FR), reaching was performed during quiet standing. In up-and-reach (UR), subjects stood up from a seated position and then reached forward. A motion analysis system was used to calculate the location of the center of mass (COM) and joint angles at the initial and final positions, and the finger, COM, and joint angular displacements during the reaching task. For both groups, UR was initiated in a more flexed posture and had a significantly shorter reach distance and greater ankle dorsiflexion angle, compared to FR. The location of the COM, however, did not differ between the two task conditions. Older adults were found to significantly slow down their downward and forward COM motions in UR but not young adults. These findings showed that a preceding balance task increased the task demand and required modifications in the movement strategy. For older adults, the impact of increased task demand was greater, and adopting a cautious strategy could help to complete the task safely.

How does knee pain affect trunk and knee motion during badminton forehand lunges

Abstract Badminton requires extensive lower extremity movement and a precise coordination of the upper extremity and trunk movements. Accordingly, this study investigated motions of the trunk and the knee, control of dynamic stability and muscle activation patterns of individuals with and without knee pain. Seventeen participants with chronic knee pain and 17 healthy participants participated in the study and performed forehand forward and backward diagonal lunges. This study showed that those with knee pain exhibited smaller knee motions in frontal and horizontal planes during forward lunge but greater knee motions in sagittal plane during backward lunge. By contrast, in both tasks, the injured group showed a smaller value on the activation level of the paraspinal muscles in pre-impact phase, hip–shoulder separation angle, trunk forward inclination range and peak centre of mass (COM) velocity. Badminton players with knee pain adopt a more conservative movement pattern of the knee to minimise recurrence of knee pain. The healthy group exhibit better weight-shifting ability due to a greater control of the trunk and knee muscles. Training programmes for badminton players with knee pain should be designed to improve both the neuromuscular control and muscle strength of the core muscles and the knee extensor with focus on the backward lunge motion.

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

Atherosclerosis is considered to be a form of chronic inflammation and a disorder of lipid metabolism. Oxidative transformations in the lipid and apolipoprotein B (Apo B) constituent of low density lipoprotein drive the initial step in atherogenesis due to macrophage scavenger receptors identify oxidized LDL (oxLDL) but non-oxidized LDL. The human vascular endothelial cells fact a critical role in vasodilation, provides a nonadhesive surface for circulation, reduces vascular smooth muscle proliferation, inflammation, thrombus formation and platelet aggregation. Assembly of oxLDL contribute to stimulation of endothelial cells with up-regulation of adhesion molecules, increase oxidative stress to the vascular endothelium and inhibition of NO-mediated vasodilation. When adhesion molecules are over-expressed on the surface of endothelial cells under oxLDL stimulation, it will recruit monocytes to the arterial wall. Then adherent monocytes will migrate into the subendothelial space and subsequently differentiate into macrophages. In the subendothelial space, oxLDL will be taken up by macrophages, thereby causing the substantial cholesterol accumulation and the foam cells production.

Steadiness of Spinal Regions during Single-Leg Standing in Older Adults with and without Chronic Low Back Pain

The aims of this study were to compare the steadiness index of spinal regions during single-leg standing in older adults with and without chronic low back pain (LBP) and to correlate measurements of steadiness index with the performance of clinical balance tests. Thirteen community-dwelling older adults (aged 55 years or above) with chronic LBP and 13 age- and gender-matched asymptomatic volunteers participated in this study. Data collection was conducted in a university research laboratory. Measurements were steadiness index of spinal regions (trunk, thoracic spine, lumbar spine, and pelvis) during single-leg standing including relative holding time (RHT) and relative standstill time (RST), and clinical balance tests (timed up and go test and 5-repetition sit to stand test). The LBP group had a statistically significantly smaller RHT than the control group, regardless of one leg stance on the painful or non-painful sides. The RSTs on the painful side leg in the LBP group were not statistically significantly different from the average RSTs of both legs in the control group; however, the RSTs on the non-painful side leg in the LBP group were statistically significantly smaller than those in the control group for the trunk, thoracic spine, and lumbar spine. No statistically significant intra-group differences were found in the RHTs and RSTs between the painful and non-painful side legs in the LBP group. Measurements of clinical balance tests also showed insignificant weak to moderate correlations with steadiness index. In conclusion, older adults with chronic LBP demonstrated decreased spinal steadiness not only in the symptomatic lumbar spine but also in the other spinal regions within the kinetic chain of the spine. When treating older adults with chronic LBP, clinicians may also need to examine their balance performance and spinal steadiness during balance challenging tests.

Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure

OxLDL facilitate reactive oxygen species (ROS) formation and up-regulation of the executioner caspase-3 via the mitochondrial apoptotic pathway involves several critical steps in human endothelial cells. Previous studies reported that oxLDL-facilitated endothelial oxidative stress is associated with impairment of eNOS and up-regulation of inducible nitric oxide synthase (iNOS). Baicalein is the most abundant component that has anti-HIV, anti-tumor, anti-oxidant and free radical scavenging functions. In this present study, we shown that baicalein hinibits oxLDL-caused endothelial dysfunction through suppression of endothelial inflammation and oxidative stress that causes to cellular apoptosis. Specifically, baicalein reduces the elevation of ROS concentration, which subsequently inhibits the oxLDL-decreased expression of anti-oxidant enzymes, enriches the bioavailability of NO, stabilizes the mitochondrial membrane, thereby inhibiting the discharge of cytochrome c from mitochondria, a molecule required for the activation of the pro-apoptotic protein caspase 3. However, inhibition of eNOS impairs the anti-apoptotic and anti-inflammatory effects of baicalein. These results provide new insight into the possible molecular mechanisms by which baicalein protects against atherogenesis by NO-related pathways.

The Influence of Footwear Sole Hardness on Slip Characteristics and Slip‐Induced Falls in Young Adults

Theoretically, a shoe that provides less friction could result in a greater slip distance and foot slipping velocity, thereby increasing the likelihood of falling. The purpose of this study was to investigate the effects of sole hardness on the probability of slip‐induced falls. Forty young adults were randomized into a hard or a soft sole shoe group, and tested under both nonslippery and slippery floor conditions using a motion analysis system. The proportions of fall events in the hard‐ and soft‐soled shoe groups were not statistically different. No differences were observed between shoe groups for average slip distance, peak and average heel velocity, and center of mass slipping velocity. A strong association was found between slip distance and the fall probability. Our results demonstrate that the probability of a slip‐induced fall was not influenced by shoe hardness. Once a slip is induced, slip distance was the primary predictor of a slip‐induced fall.