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Featured researches published by Yi-Qun Shi.


Bioorganic & Medicinal Chemistry Letters | 1999

Metallopeptide approach to the design of biologically active ligands: design of specific human neutrophil elastase inhibitors.

Yi-Qun Shi; Shubh Sharma

A series of compounds was designed to inhibit human neutrophil elastase utilizing a modified metallopeptide scheme developed in our laboratory termed metal-ion induced distinctive array of structures (MIDAS). These metallopeptides, synthesized by solution and solid-phase methods, exhibited excellent structural diversity and specificity in inhibiting human neutrophil elastase.


Archive | 1999

Metallopeptide combinatorial libraries and applications

Shubh D. Sharma; Yi-Qun Shi


Archive | 2002

Peptidomimetics of biologically active metallopeptides

Shubh D. Sharma; Yi-Qun Shi; Zhijun Wu; Ramesh Rajpurohit


Archive | 2005

Cyclic peptides for treatment of cachexia

Shubh D. Sharma; Ramesh Rajpurohit; Annette M. Shadiack; Yi-Qun Shi; Kevin D. Burris


Archive | 2005

Substituted melanocortin receptor-specific piperazine compounds

Shubh D. Sharma; Yi-Qun Shi; Ramesh Rajpurohit; Zhijun Wu


Archive | 2005

Naphthalene-containing melanocortin receptor-specific small molecule

Shubh D. Sharma; Annette M. Shadiack; Yi-Qun Shi; Zhijun Wu; Ramesh Rajpurohit; Kevin D. Burris; Papireddy Purma


Archive | 2005

Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds

Shubh D. Sharma; Yi-Qun Shi


Archive | 2000

MELANOCORTIN METALLOPEPTIDE CONSTRUCTS, COMBINATORIAL LIBRARIES AND APPLICATIONS

Shubh D. Sharma; Yi-Qun Shi; Wei Yang; Hui-Zhi Cai


Archive | 2004

Melanocortin Receptor-Specific Compounds

Shubh D. Sharma; Yi-Qun Shi; Ramesh Rajpurohit; Zhijun Wu; Papireddy Purma; Annette M. Shadiack; Kevin D. Burris


Archive | 2004

Bicyclic melanocortin-specific compounds

Shubh D. Sharma; Yi-Qun Shi; Zhijun Wu; Ramesh Rajpurohit

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