Yoichi Kimura
Daiichi Sankyo
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Publication
Featured researches published by Yoichi Kimura.
Bioorganic & Medicinal Chemistry Letters | 2010
Hiroshi Takeshita; Jun Watanabe; Yoichi Kimura; Katsuhiro Kawakami; Hisashi Takahashi; Makoto Takemura; Akihiro Kitamura; Kazuhiko Someya; Ryohei Nakajima
Based on the HTS hit compound 1a, an inhibitor of beta-1,6-glucan synthesis, we synthesized novel pyridobenzimidazole derivatives and evaluated their antifungal activity. Among the compounds synthesized, we identified the potent compound 15e, which exhibits excellent activity superior to fluconazole against both Candida glabrata and Candida krusei. From the SAR study, we revealed essential moieties for antifungal activity.
Archive | 1992
Yusuke Yukimoto; Tohru Kaneuchi; Yoichi Kimura; Katsuhiro Kawakami; Isao Hayakawa
Archive | 1992
Toshihiko Horibe; Shigeo Itagaki; Yoichi Kimura; Koji Narisawa; Seiji Saito; Kazuya Taki; Yoshinori Yoshida; 好徳 吉田; 敏彦 堀部; 孝司 成澤; 誠治 斉藤; 陽一 木村; 茂男 板垣; 和也 瀧
Archive | 1993
Yoichi Kimura; Norikazu Matsuhashi; Makoto Takemura; 陽一 木村; 範一 松橋; 真 竹村
Archive | 1992
Takeshi Hayano; Yoichi Kimura; Hisashi Takahashi; 健 早野; 陽一 木村; 寿 高橋
Archive | 1997
Yusuke Yukimoto; Tohru Kaneuchi; Yoichi Kimura; Katsuhiro Kawakami; Isao Hayakawa
Archive | 1993
Yoichi Kimura; Toshihiko Horibe; Koji Watanabe
Archive | 1993
Yoichi Kimura; Toshihiko Horibe; Koji Watanabe
Archive | 1992
Yusuke Yukimoto; Yoichi Kimura; Isao Hayakawa; Tohru Kaneuchi; Katsuhiro Kawakami
Archive | 1991
Isao Hayakawa; Katsuhiro Kawakami; Yusuke Yukimoto; Tohru Kaneuchi; Yoichi Kimura
