Yong Xin

Rh2(OAc)4 catalyzed formation of fluorine-containing polysubstituted furans from diazocompounds and aromatic alkynes

A new building block strategy for the synthesis Of fluorine-containing 1,2,4-trisubstituted furan was reported The 1,2,4-trisubstituted furan was constructed through [3+2] cycloaddition reaction of fluoroacetyl-containing diazocompound and aromatic alkyne, catalyzed by Rh-2(OAc)(4) (C) 2009 Elsevier Ltd All rights reserved

Three-component reactions involving quinoline or isoquinoline, dialkyl acetylenedicarboxylate and β-trifluoroacetyl vinyl ethyl ether

The three-component reactions (TCRs) involving quinoline or isoquinoline, dialkyl acetylenedicarboxylate and beta-trifluoroacetyl vinyl ethyl ether were investigated. The reaction proceeded smoothly under ambient temperature in DMSO to give the 4-trifluoroacetyl substituted benzo[c]quinolizine derivatives in moderate yields. However, under the same reaction condition, isoquinoline afforded the 2-trifluoromethyl substituted 1-oxa-(11H)-benzo[a]dihydroquinolizine or 4-trifluoroacetyl substituted benzo[a]clihydroquinolizine products. The possible reaction pathways were proposed