Yongning Wu

Dietary intake of mercury by children and adults in Jinhu area of China.

Dietary intakes of mercury by children and adults in Jinhu area of China were determined using a duplicate diet approach. A total of 176 duplicate diet portions were collected from 60 individuals in November and December of 2007. Mercury levels in duplicate samples were measured by atomic fluorescence spectrometry. The daily mercury intakes (median and range) from consumption days without fish or shellfish for children and adults were 0.13 (0.05-0.78) μg(kg(bw))(-1) day(-1) and 0.07 (0.04-0.18) μg(kg(bw))(-1) day(-1), respectively, which were significantly lower than those from consumption days with fish or shellfish for both children and adults whose daily intakes (median and range) were 0.16 (0.11-0.84) μg(kg(bw))(-1) day(-1) and 0.09 (0.05-0.46) μg(kg(bw))(-1) day(-1), respectively. The exposure level of children was significantly higher than that of adults. The 50th and 99th percentile of the usual mercury intake from all consumption days for children were 0.14 and 0.22 μg(kg(bw))(-1) day(-1) and for adults were 0.09 and 0.14 μg(kg(bw))(-1) day(-1), where the between-person variance in dietary mercury intake for children and adults were 0.038 and 0.036, respectively. Comparing with the provisional tolerable weekly intake (PTWI) divided into daily intake (PTDI) of 0.57 μg(kg(bw))(-1) day(-1), it is concluded that the average daily intakes and the usual intakes to mercury can be considered safe for both children and adults in Jinhu area by the duplicate diet study. But the maximum daily intakes for children exceeding the PTDI deserve a close attention.

Long-term dietary exposure to lead of the population of Jiangsu Province, China

Deterministic and probabilistic estimates of the chronic exposure to lead (Pb) for the inhabitants in Jiangsu Province, China, were performed. Pb contamination data were obtained from the national food contamination monitoring programme during 2001–2006 and 2600 samples from 38 commodities in Jiangsu were included. Food consumption data were from the national diet and nutrition survey conducted in 2002, including 3879 subjects aged 2–80 years and 185 children aged 2–6 years in Jiangsu. Contributions from 38 commodities were included in the calculations. Using the provisional tolerable weekly intakes (PTWI) divided into daily intakes (PTWId) of 3.57 µg kg−1 bw day−1 in the risk assessment, exposures calculated by the deterministic approach for children and the general population were 77% and 43% of the PTWId, respectively, which were nearly similar to the mean intake calculation in the probabilistic approach. The percentage of people whose exposure level exceeded the PTWId for children, the general population, urban population and rural population were 16%, 0.4%, 0.1%, and 0.5%, respectively. The 50th, 95th and 99th percentiles of Pb exposure for children were 2.6, 4.4 and 5.5 µg kg−1 bw day−1, respectively. Rice followed by wheat flour and bean products contributed most to the total Pb intake for both children and the general population. This study indicated that the Pb dietary exposure in Jiangsu Province, especially for children, would be a public health concern.

Dietary exposure to lead by children and adults in the Jinhu area of China

This paper reports an estimate of the dietary intake of lead by children and adults from the Jinhu area in South-eastern China. A duplicate diet approach was used to collect food samples in November and December 2007. The lead content was measured by furnace atomic absorption spectrometry. Median lead intakes for different groups were as follows: children: 1.65 µg(kgbw)−1 day−1; and adults: 1.10 µg(kgbw)−1 day−1. No exposure exceeded the provisional tolerable weekly intake (PTWI) of 25 µg(kgbw)−1 week−1 proposed by the World Health Organization (WHO). However, median and maximum exposure for the children group amounted to 60.8% and 97.2% of the PTWI, respectively, which were higher than those for adults, which were 40.5% and 86.4%, respectively. It was concluded that health risks due to dietary lead intake seem to be high in Jinhu.

Dietary exposure and risk assessment to lead of the population of Jiangsu province, China

The paper’s main purpose is to estimate the dietary exposure to lead for the inhabitants of Jiangsu province, China. Lead concentration data were obtained from the national food contamination monitoring programme during 2007–10. Food samples (n = 2077) were collected from 23 food categories in Jiangsu province. Consumption data were derived from Chinese national nutrition and health survey in 2002, which included 3938 inhabitants from 1451 households in Jiangsu province. Concentration data were combined with consumption data to estimate the dietary intake for the inhabitants of 2–6, 7–17 and 18–80 years, respectively. The β-binomial–normal (BBN) model was used to estimate the long-term intake for the population in Jiangsu province. The distribution of individual margin of exposure (IMoE) was introduced to assess the health effect. Uncertainty of IMoE was quantified by Monte Carlo and bootstrap methods. The mean levels of dietary exposure to lead were estimated at 3.019 µg kg−1 bw day−1 for children aged 2–6 years, 2.104 µg kg−1 bw day−1 for teenagers aged 7–17 years, and 1.601 µg kg−1 bw day−1 for adults aged 18–80 years. The mean intakes for the urban and rural populations were 1.494 and 1.822 µg kg−1 bw day−1, respectively. From the 25th to 99.9th percentiles, IMoE was 0.125–2.057 for 2–6 years and 0.473–7.998 for 18–80 years, respectively. The distribution of IMoE could indicate a public health concern on lead for the Chinese population in Jiangsu. Control measures should be taken to reduce lead exposure in Jiangsu province.

Calculation of the dietary exposure of Chinese consumers to acephate residues using deterministic and probabilistic approaches

This paper compares the exposure for the Chinese populations and sub-groups to acephate, a widely applied organophosphorus pesticide, using deterministic and probabilistic approaches. Acephate residue data were obtained from the national food contamination monitoring program 2001–2006, collected by multi-stage stratified sampling and with a detection rate of 3.3%. Food consumption data were gathered from the national diet and nutrition survey conducted in 2002 over three consecutive days by the 24-h recall method, and included 22,563 families or 65,886 consumers aged 2–100 years. For point estimate, it was evident that exposures were higher than the acute reference dose (ARfD) in many cases. For the probabilistic approach, the P99.9 exposures for the general population and children accounted for 11.88 and 24.15% of the ARfD, respectively, in acute intake calculations and 52.86 and 68.75%, respectively, of the acceptable daily intake (ADI) in chronic intake calculations. The exposure level of rural people was higher than urban dwellers, and vegetables contributed most to acephate intake.

Probabilistic acute dietary exposure assessment of the Chinese population to cypermethrin residues

A probabilistic estimation of dietary exposure to cypermethrin residues for the Chinese population was performed. Cypermethrin residue data were obtained from the national food contamination monitoring program for 2001–2006, encompassing 14,096 samples from 36 commodities with a detection rate of 10.4%. Food consumption data were gathered from the national nutrition and health survey conducted in 2002, comprising 65,915 consumers aged 2–100 years and 3701 children of 2–6 years old. The whole country was roughly divided into six regions and the ranges of the median and of P99.9 exposure estimated for these regions were 0.018–0.026 and 3.131–7.095 µg kg−1 bw day−1, respectively. Pak-choi and Chinese cabbage contributed 33.9 and 13.2%, respectively, to the cypermethrin intake for the general population, while pak-choi and citrus covered 30.7 and 22.5% of the total intake for children, respectively. The exposure of the rural population was higher than urban populations. Rural areas mainly located in the plains of central China had among the highest exposure of the six regions, accounting for 17.7% of the ARfD at P99.9, while the 99.99th percentile of exposure for children, especially rural children, far exceeded the ARfD, which is a cause for concern.

Dietary intake of arsenic by children and adults from Jinhu area of China

The aim of this study was to estimate the dietary intake of arsenic (As) by children and adults from Jinhu area of China. A duplicate diet approach was used to collect diet samples in November and December 2007. The As content was measured by hydride generation atomic fluorescence spectrometry. The As intakes (median) for different group were: children: 0.6 µg kg−1 bw day−1 or 6.7 µg kg−1 bw week−1; adults: 0.5 µg kg −1 bw day−1 or 3.8 µg kg −1 bw week−1, none of which exceeded the provisional tolerable weekly intake (PTWI) of 15 µg kg −1 bw week−1 for As proposed by the World Health Organization (WHO). The median and maximum of the children group amounted to 44.7% and 125.3% of the PTWI; the values for adults were 25.3% and 118.7%, respectively. There were 3.3% of children whose weekly As intake exceeded the PTWI, and there were 6.7% of adults whose weekly As intake exceeded the PTWI. It is concluded that dietary As intake was safe for most people in Jinhu area, but the high dietary As intake for a minority of people in this area deserves attention.

Dietary exposure and risk assessment to cadmium of the adult population of Jiangsu province, China: Comparing between semi-probabilistic and fully probabilistic approaches

ABSTRACT With rapid industrialization and modernization in China, long-term dietary exposure to cadmium (Cd) has the potential to cause health risks. The traditional probabilistic approach for long-term dietary assessment was a semi-probabilistic method that had limitations in qualifying the variation in concentration data. Thus, this article estimated the long-term dietary exposure to Cd of the adults of Jiangsu province using semi-probabilistic and fully probabilistic approaches, and compared the two models. Cd concentration data were obtained from the national food contamination monitoring program 2001–2009. Food consumption data were gathered from the National Diet and Nutrition Survey conducted in 2002. The provisional tolerable daily intakes (PTDI) of 0.8 μg kg–1 bw for Cd was applied in the risk assessment. The estimates of semi-probabilistic approach were within the provisional tolerable daily intakes (PTDI) at mean and all percentiles. However, the P95 of exposure with fully probabilistic approach for all population groups were above PTDI. Rice and rice products followed by wheat flour and wheat flour products, crustaceans, pak-choi, beans, and bean products contributed most to the Cd intake for adults. The fully probabilistic estimates could indicate a possible public health concern on Cd for adults in Jiangsu province.