Yongsheng Huang
University of Arkansas for Medical Sciences
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Yongsheng Huang.
Oncogene | 2005
Atsushi Suzuki; Shinsuke Iida; Emi Tajima; Fenghuang Zhan; Ichiro Hanamura; Yongsheng Huang; Tsutomu Ogura; Satoru Takahashi; Ryuzo Ueda; Bart Barlogie; John D. Shaughnessy; Hiroyasu Esumi
ARK5, AMP-activated protein kinase (AMPK)-related protein kinase mediating Akt signals, is closely involved in tumor progression, and its stage-associated expression was observed in colorectal cancer. In this study, we found ARK5 expression in multiple myeloma cell lines expressing c-MAF and MAFB. In addition, gene expression profiling of 351 clinical specimens revealed ARK5 expression in primary myelomas expressing c-MAF and MAFB, suggesting that ARK5 may be a transcriptional target of the Large-MAF family. Sequence analysis of the ARK5 gene promoter revealed that it contains two putative MAF-recognition element (MARE) sequences. In support of this hypothesis, ARK5 was induced when an MAFB or c-MAF expression vector was introduced into non-ARK5-expressing colon cancer cells. Furthermore, ARK5 promoter activity was dramatically decreased by mutation or deletion of MARE sequences. Chromatin immunoprecipitation assays revealed an interaction between the Large-MAF family proteins and MARE sequences in the ARK5 promoter. Moreover, in ARK5 mRNA-expressing multiple myeloma lines, but not in ARK5-negative lines, insulin-like growth factor (IGF)-1 increased invasion activity. IGF-1-induced invasion was reproduced when ARK5 was overexpressed in Burkitts lymphoma and plasmacytoma lines. Based on results, we conclude that ARK5 is a transcriptional target of the Large-MAF family through MARE sequence and that ARK5 may in part mediate the aggressive phenotype associated with c-MAF- and MAFB-expressing myelomas.
Leukemia | 2006
Ichiro Hanamura; Yongsheng Huang; Fenghuang Zhan; B Barlogie; John D. Shaughnessy
Prognostic value of Cyclin D2 mRNA expression in newly diagnosed multiple myeloma treated with high-dose chemotherapy and tandem autologous stem cell transplantations
Blood | 2006
Fenghuang Zhan; Yongsheng Huang; Simona Colla; James P. Stewart; Ichiro Hanamura; Sushil Gupta; Joshua Epstein; Shmuel Yaccoby; Jeffrey R. Sawyer; Bart Burington; Elias Anaissie; Klaus Hollmig; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Ronald Walker; Maurizio Zangari; John Crowley; Bart Barlogie; John D. Shaughnessy
Blood | 2007
John D. Shaughnessy; Fenghuang Zhan; Bart Burington; Yongsheng Huang; Simona Colla; Ichiro Hanamura; James P. Stewart; Bob Kordsmeier; Christopher Randolph; David R. Williams; Yan Xiao; Hongwei Xu; Joshua Epstein; Elias Anaissie; Somashekar G. Krishna; Michele Cottler-Fox; Klaus Hollmig; Abid Mohiuddin; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Jeffrey R. Sawyer; Yazan Alsayed; Ronald Walker; Maurizio Zangari; John Crowley; Bart Barlogie
Cancer Cell | 2006
Daniel R. Carrasco; Giovanni Tonon; Yongsheng Huang; Yunyu Zhang; Raktim Sinha; Bin Feng; James P. Stewart; Fenghuang Zhan; Deepak Khatry; Marina Protopopova; Alexei Protopopov; Kumar Sukhdeo; Ichiro Hanamura; Owen Stephens; Bart Barlogie; Kenneth C. Anderson; Lynda Chin; John D. Shaughnessy; Cameron Brennan; Ronald A. DePinho
Blood | 2006
Ichiro Hanamura; James P. Stewart; Yongsheng Huang; Fenghuang Zhan; Madhumita Santra; Jeffrey R. Sawyer; Klaus Hollmig; Maurizio Zangarri; Mauricio Pineda-Roman; Frits van Rhee; Federica Cavallo; Bart Burington; John Crowley; Guido Tricot; Bart Barlogie; John D. Shaughnessy
Blood | 2007
George Mulligan; Constantine S. Mitsiades; Barb Bryant; Fenghuang Zhan; Wee J. Chng; Steven Roels; Erik Koenig; Andrew M. Fergus; Yongsheng Huang; Paul G. Richardson; William L. Trepicchio; Annemiek Broyl; Pieter Sonneveld; John D. Shaughnessy; Leif Bergsagel; David P. Schenkein; Dixie-Lee Esseltine; Anthony Boral; Kenneth C. Anderson
Blood | 2007
Fenghuang Zhan; Bart Barlogie; Varant Arzoumanian; Yongsheng Huang; David R. Williams; Klaus Hollmig; Mauricio Pineda-Roman; Guido Tricot; Frits van Rhee; Maurizio Zangari; Madhav V. Dhodapkar; John D. Shaughnessy
Blood | 2004
Fenghuang Zhan; Jeffrey R. Sawyer; Sushil Gupta; Yongsheng Huang; Elias Anaissie; Hongwei Xu; Ichior Hanamura; Madhumita Santra; Maurizio Zangari; Choon-Kee Lee; Athanasios Fassas; Frits van Rhee; Klaus Hollmig; Giampaolo Talamo; Raymond Thertulian; Guido Tricot; William Barlow; Erik Rasmussen; John Crowley; Bart Barlogie; Shaughnessy John
Blood | 2006
John D. Shaughnessy; Jeff Haessler; Jerry Zeldis; Yongsheng Huang; Fenghuang Zhan; Jeffrey R. Sawyer; Elias Anaissie; Frits van Rhee; Guido Tricot; Joshua Epstein; Maurizio Zangari; Mauricio Pineda-Roman; Klaus Hollmig; John Crowley; Bart Barlogie
Collaboration
Dive into the Yongsheng Huang's collaboration.
