Yoon Young Jung

A Rat Esophageal Model to Investigate Stent-induced Tissue Hyperplasia

PURPOSE To evaluate the feasibility of stent placement and the formation of tissue hyperplasia caused by stent placement in a rat esophageal model. MATERIALS AND METHODS Twenty Sprague-Dawley rats were divided into four groups to assess differing stent diameters and design (group I, 4 mm diameter and a large mesh gap; group II, 5 mm diameter and a large mesh gap; group III, 5 mm diameter and a small mesh gap; and group IV, barbs added to the group III stents). Follow-up, 1-week, and 3-week esophagograms were obtained. Rats were euthanized 3 weeks after stent placement. Microscopic findings were evaluated in groups with an incidence of less than 50% stent migration. RESULTS Stent placement was technically successful in all rats, and there were no procedure-related complications. No esophageal perforation occurred during follow-up. The incidence of stent migration was 100%, 60%, 40%, and 0% in groups I through IV, respectively. The esophagi with stent migration showed only a small amount of tissue hyperplasia; however, esophagi without stent migration showed gross tissue hyperplasia through the mesh. The microscopic findings were evaluated in groups III and IV. The degree of inflammatory cell infiltration, papillary projection thickness, granulation tissue area, and percentage of the granulation tissue area were higher in group IV than in group III; however, there was no statistical significance. CONCLUSIONS Esophageal stent placement was feasible in a rat model, and formation of tissue hyperplasia was evident in rats without stent migration. With barbed stents, there was the least incidence of stent migration without esophageal perforation.

Rapidly aggravated dissecting flap by angiography during percutaneous stent placement for acute isolated superior mesenteric artery dissection.

Acutely aggravated dissecting flap and consequent occlusion of the superior mesenteric artery (SMA) by simple contrast passage during initial angiography for percutaneous stent placement is a uncommon event, which usually is not reported. After analysis of many factors that underlie development of such complications, we present herein one case of successful treatment of isolated SMA dissection and its complications with favorable outcomes during 25 months follow-up after percutaneous stent placement.

Increased risk of asymptomatic gallstones in patients with ulcerative colitis.

Background/Aims The relationship between Crohns disease and gallstones is established. However, the prevalence and risk factors for gallstones in patients with ulcerative colitis (UC) are not yet well understood. The aim of this study was to evaluate the prevalence and risk factors of gallstones in patients with UC. Methods This study was a retrospective single center study. A total of 87 patients with UC and 261 healthy controls were enrolled. Age, sex, and body mass index were matched. To investigate risk factors, the extent of UC, duration of disease, number of hospital admissions, and number of steroid treatments in patients with UC were evaluated. Results The prevalence of gallstones in patients with UC was 13.8%, whereas that in healthy controls was only 3.1% (P<0.001). For patients with UC, patients ≥50 years of age had a 3.6-times higher risk of gallstones compared to that in those <50 years of age, and the difference was statistically significant (odds ratio, 3.60; confidence interval, 1.03-12.61) in univariate analysis. There were no statistically significant disease-related risk factors for gallstones in UC patients. Conclusions This is the first study of gallstone prevalence in Korean UC patients. In this study, patients with UC had a higher prevalence of gallstones compared to that in well-matched healthy controls. Age seemed to be a possible risk factor, and more studies are needed. Further prospective, large-scale studies will be required to confirm the risk factors for gallstones in UC patients.

Total Ankle Arthroplasty: An Imaging Overview

With advances in implant technology, total ankle arthroplasty (TAA) has become an increasingly popular alternative to arthrodesis for the management of end-stage ankle arthritis. However, reports in the literature do not focus on the imaging features of TAA. Through a literature review, we demonstrate basic design features of the current ankle arthroplasty system, and the normal and abnormal postoperative imaging features associated with such devices. Pre- and postoperative evaluations of ankle arthroplasty mainly include radiography; in addition, computed tomography and magnetic resonance imaging provide further characterization of imaging abnormalities. Familiarization with multimodal imaging features of frequent procedural complications at various postoperative intervals is important in radiological practice.

Emphysematous Pyelonephritis Caused by Citrobacter freundii in a Patient with Type 2 Diabetes and Neurogenic Bladder

Emphysematous pyelonephritis (EPN) is a rare, life-threatening complication of upper urinary tract infections that is characterized by the presence of gas in the renal parenchyma and perirenal space. It commonly occurs in diabetic patients. Escherichia coli are the most common causative organisms, with few reports implicating Citrobacter freundii as the etiologic agent in EPN. A 57-year-old woman with diabetes and neurogenic bladder visited at our department with confused mentality, myalgia, and general weakness. Further investigation revealed that the patient suffered from unilateral EPN with sepsis caused by C. freundii. The patients condition was improved considerably with percutaneous drainage and use of intravenous antibiotics for several weeks. However, renal function eventually deteriorated to permanent renal failure, which required hemodialysis. In conclusion, C. freundii may be the causative pathogen of EPN in a patient with type 2 diabetes and neurogenic bladder.

A Pulmonary Sequestered Segment with an Aberrant Pulmonary Arterial Supply: A Case of Unique Anomaly.

We presented a rare case of a 64-year-old man with a combined anomaly of the bronchus and pulmonary artery that was detected incidentally. Computed tomography showed a hyperlucent, aerated sequestered segment of the right lower lung with an independent ectopic bronchus, which had no connection to the other airway. The affected segment was supplied by its own aberrant pulmonary artery branch from the right pulmonary trunk. This anomaly cannot be classified with any of the previously reported anomalies.