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Dive into the research topics where Yoshie Shimura is active.

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Featured researches published by Yoshie Shimura.


Hormone Research in Paediatrics | 1999

Association of angiotensin-converting enzyme gene polymorphism with lipid profiles in children and adolescents with insulin-dependent diabetes mellitus.

Kisho Kobayashi; Shin Amemiya; Mie Mochizuki; Koji Kobayashi; Kyoko Matsushita; Emi Sawanobori; Toshihide Ishihara; Kosuke Higashida; Yoshie Shimura; Kiyohiko Kato; Shinpei Nakazawa

We attempted to clarify the association between angiotensin-converting enzyme (ACE) gene polymorphism and the other predictive factors for macroangiopathy in children and adolescents with uncomplicated insulin-dependent diabetes mellitus (IDDM). Sixty-three patients were divided into 3 groups according to the ACE genotypes. The lipid profiles were evaluated according to ACE genotypes. The level of lipoprotein(a) (Lp(a)) in the II genotype was significantly lower than that in groups with the D allele. Lp(a) significantly correlated with apo B/apo A-I (p < 0.001, r = 0.63) and atherogenic index (AI = (total cholesterol – high-density lipoprotein cholesterol)/high-density lipoprotein cholesterol; p = 0.004, r = 0.36). We suggest that the D allele may affect the level of Lp(a) and the other lipid profiles in IDDM.


Diabetes Care | 2003

Association of the CTLA-4 Gene 49 A/G Polymorphism With Type 1 Diabetes and Autoimmune Thyroid Disease in Japanese Children

Mie Mochizuki; Shin Amemiya; Kisho Kobayashi; Koji Kobayashi; Yoshie Shimura; Toshihide Ishihara; Yoshiko Nakagomi; Kazumichi Onigata; Shinya Tamai; Akira Kasuga; Shinpei Nanazawa


Human Genetics | 2003

Functional polymorphisms in the mineralocorticoid receptor and amirolide-sensitive sodium channel genes in a patient with sporadic pseudohypoaldosteronism

Keiko Arai; Yoshiko Nakagomi; Mitsue Iketani; Yoshie Shimura; Shin Amemiya; Kenji Ohyama; Tamotsu Shibasaki


Endocrine Journal | 1995

Effects of Growth Hormone and Insulin-Like Growth Factor I on Testosterone Secretion in Premature Male Rats.

Kenji Ohyama; Masanori Ohta; Yoshiko Nakagomi; Toshitsugu Yamori; Tomoaki Sano; Yoshie Shimura; Kazumasa Sato; Shinpei Nakazawa


Endocrine Journal | 2002

Effects of Growth Hormone on Testicular Dysfunction Induced by Cyclophosphamide (CP) in GH-Deficient Rats

Kazumasa Satoh; Kenji Ohyama; Yoshiko Nakagomi; Masanori Ohta; Yoshie Shimura; Tomoaki Sano; Hiromichi Ishikawa; S Amemiya; Shinpei Nakazawa


Endocrine Journal | 1999

Growth Hormone Advances Spermatogenesis in Premature Rats Treated with Gonadotropin-Releasing Hormone Agonist.

Kenji Ohyama; Noritaka Iwatani; Yoshiko Nakagomi; Masanori Ohta; Yoshie Shimura; Tomoaki Sano; Kazumasa Sato; Rika Ohno; Hiroyo Mabe; Hiromichi Ishikawa; Shinpei Nakazawa


Journal of Veterinary Medical Science | 2007

Maternal Exposure of Low Dose of TCDD Modulates the Expression of Estrogen Receptor Subunits of Male Gonads in Offspring

Kenji Ohyama; Masanori Ohta; Tomoaki Sano; Kazumasa Sato; Yoshiko Nakagomi; Yoshie Shimura; Yoshiaki Yamano


Biochemical and Biophysical Research Communications | 2009

Expression of stanniocalcin-1 in gastrointestinal tracts of neonatal and mature rats.

Rika Kobayashi; Yoshiko Nakagomi; Yoshie Shimura; Mie Mochizuki; Kisho Kobayashi; Kanji Sugita; Kenji Ohyama


Endocrine Journal | 1997

Restoration of Seminiferous Tubular Function after Discontinuation of Long-Term Gonadotropin-Releasing Hormone Agonist Administration in Premature Male Rats

Kenji Ohyama; Masanori Ohta; Yoshiko Nakagomi; Yoshie Shimura; Tomoaki Sano; Kazumasa Sato; Shinpei Nakazawa; Hiromichi Ishikawa


Clinical Pediatric Endocrinology | 1993

Interrelationship of Urinary Growth Hormone Levels, Obesity Index, Growth Velocity, and Bone Maturation: A Study in Groups of 7 and 10 year-old Children

Yoshiko Nakagomi; Kenji Ohyama; Masatoshi Fujimoto; Masanori Ota; Toshitsugu Yamori; Yoshie Shimura; Tomoaki Sano; Kiyohiko Kato

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Kenji Ohyama

University of Yamanashi

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Tomoaki Sano

University of Yamanashi

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S Amemiya

University of Yamanashi

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Shin Amemiya

Yokohama City University

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