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Publication
Featured researches published by Yoshie Yoshikawa.
Japanese Journal of Cancer Research | 2000
Yoshie Yoshikawa; Hiroyuki Mukai; Fumitsugu Hino; Kiyozo Asada; Ikunoshin Kato
Using a differential display technique, we identified two genes that are down‐regulated in human gastric cancer tissue as compared to normal gastric mucosa. The down‐regulated expression of these genes in gastric cancer tissue was confirmed by northern blotting analysis and RT‐PCR. One, CA11, was a novel gene expressed predominantly in the stomach and was depleted in all of the gastric cancer cell lines examined. The other gene, GC36, was homologous to the digestive tract‐specific calpain gene, nCL‐4. The expression of both GC36 and nCL‐4 was suppressed or depleted in gastric cancer cell lines of differentiated and poorly differentiated types. This is the first report of genes, the expression of which is down‐regulated with considerable frequency in gastric cancer.
The Journal of Antibiotics | 1993
Kazutoh Takesako; Hiroyuki Kuroda; Toshiaki Ino-ue; Fumiyo Haruna; Yoshie Yoshikawa; Ikunoshin Kato; Katsuhisa Uchida; Tamio Hiratani; Hideyo Yamaguchi
Analytical Biochemistry | 1998
Yoshie Yoshikawa; Hiroyuki Mukai; Kiyozou Asada; Fumitsugu Hino; Ikunoshin Kato
The Journal of Antibiotics | 1987
Susumu Sano; Hiroyuki Kuroda; Mitsuhiro Ueno; Yoshie Yoshikawa; Teruya Nakamura; Akira Obayashi
Archive | 2002
Yoshie Yoshikawa; Hiroyuki Mukai; Kiyozo Asada; Fumitsugu Hino; Ikunoshin Kato
The Journal of Antibiotics | 1993
Yoshie Yoshikawa; Katsushige Ikai; Yoshihisa Umeda; Atsuko Ogawa; Kazutoh Takesako; Ikunoshin Kato; Hiroshi Naganawa
The Journal of Antibiotics | 1987
Susumu Sano; Katsushige Ikai; Yoshie Yoshikawa; Teruya Nakamura; Akira Obayashi
The Journal of Antibiotics | 1996
Kazutoh Takesako; Shigetoshi Mizutani; Hitoshi Sakakibara; Masahiro Endo; Yoshie Yoshikawa; Tomoko Masuda; Elko Sono-Koyama; Ikunoshin Kato
The Journal of Antibiotics | 1988
Yoshie Yoshikawa; Uchida H; Hiroyuki Kuroda; Teruya Nakamura; Akira Obayashi; Akio Fujii; Tomio Takeuchi
Archive | 1997
Kazutoh Takesako; Naoyuki Awadu; Yoshie Yoshikawa; Eiko Koyama; Ikunoshin Kato