Yoshifumi Nakajima

Impact of Coronary Calcium on Outcome Following Sirolimus-Eluting Stent Implantation

There remain a small but sizable number of patients who develop restenosis after sirolimus-eluting stent (SES) implantation. However, the cause of SES restenosis has not been fully elucidated. The study population consisted of 52 patients with 69 lesions who underwent noninvasive coronary imaging by 64-slice multidetector computed tomography before SES deployment. Agatston calcium scores in target lesions were measured. All patients underwent follow-up coronary angiography at 8 months. Three coronary segments (in stent, proximal edge, and distal edge) were analyzed by quantitative coronary angiography. Agatston calcium score in target lesions averaged 214.7. Late lumen losses in the proximal edge, stent, and distal edge were 0.16 ± 0.45, 0.47 ± 0.58, and 0.07 ± 0.29 mm, respectively. Lesions with restenosis at follow-up showed a trend to produce higher preprocedural calcium scores (629) compared to those without restenosis (153, p = 0.08). There was a significant positive correlation between lesion calcium score and in-stent late lumen loss (r = 0.47, p <0.01). In conclusion, assessment of coronary calcium by multidetector computed tomography might be useful to predict outcomes after SES implantation.

IMPACT OF?3/6 POLYUNSATURATED FATTY ACIDS RATIO ON THE PREVALENCE OF CORONARY ARTERY DISEASE ASSESSED BY 320-ROW CT CORONARY ANGIOGRAPHY

Previous studies have shown that eicosapentaenoic acid (EPA)/ arachidonic acid (AA) may be a marker of coronary artery disease (CAD). However, there have been few studies to assess the association of plasma EPA/AA ratio on the prevalence of CAD by using a computed tomography coronary angiography (

P-200 Prevalence of Polyvascular Disease in Patients with Coronary Artery Disease in Japanese Population

The mean of carotid IMT was 0.948±0.28mm in men and 0.881±0.22mm in women (p < 0.001). The prevalence of the MS was 31.6% in men and 45.2% in women. Mean carotid IMT increased with an increasing number of risk factors (p for trend <0.001) and carotid IMT values were 0.815mm, 0.848mm, 0.869mm, 0.889mm and 0.940mm for 0, 1, 2, 3, 4, and 5 risk factors, respectively. After adjustment, those with more components of MS had higher odds ratios for highest quartile carotid IMT compared with those without components. Carotid IMT was increased with the increasing number of components of MS. There is a strong relationship between carotid IMT and the MS. Current findings indicate the need for prevention and control of metabolic syndrome in a population of middle-aged Koreans.