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Featured researches published by Yoshihito Koguchi.


Nucleosides, Nucleotides & Nucleic Acids | 1995

Synthesis of 9-(2-Hydroxyethoxymethyl)guanine (Acyclovir) from Guanosine

Hiroshi Shiragami; Yoshihito Koguchi; Yasuhiro Tanaka; Satoshi Takamatsu; Yumiko Uchida; Takashi Ineyama; Kunisuke Izawa

Abstract A convenient synthesis of 9-(2-hydroxyethoxymethyl)guanine (acyclovir) from guanosine by chemical transpurination was developed. The isomerization of the 7-isomer to the desired 9-isomer and the purification of the 9-isomer was achieved simply by concentration, heating and further crystallization.


Archive | 1993

Crystals of N-(trans-4-isopropylcyclohexycarbonyl)-D-phenylalanine and methods for preparing them

Michito Sumikawa; Yoshihito Koguchi; Takao Ohgane; Yasuo Irie; Satoji Takahashi


Archive | 1994

Process for producing acyclic nucleosides and process for separating purine nucleosides

Kunisuke Izawa; Yoshihito Koguchi; Hiroshi Shiragami


Archive | 1994

Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them

Michito Sumikawa; Yoshihito Koguchi; Takao Ohgane; Yasuo Irie; Satoji Takahashi


Archive | 1992

Transglycosilation process for producing acyclic nucleosides

Hiroshi Shiragami; Yoshihito Koguchi; Kunisuke Izawa


Archive | 2003

Novel nateglinide crystal

Yoshihito Koguchi; Tomoko c Nakao; Michito Sumikawa


Archive | 2002

Method for producing beta-D-ribofuranose derivatives or optical isomers thereof

Yoshihito Koguchi; Takayoshi Torii; Kunisuke Izawa


Archive | 2010

New nateglinide crystals

Yoshihito Koguchi; Tomoko c Nakao; Michito Sumikawa


Archive | 1994

Cristaux de n-(trans-4-isopropylcyclohexylcarbonyl)- d-phenylalanine et methodes pour les preparer

Michito Sumikawa; Yoshihito Koguchi; Takao Ohgane; Yasuo Irie; Satoji Takahashi


Archive | 1992

Kristalle von N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanin und Verfahren zu ihrer Herstellung

Michito Sumikawa; Yoshihito Koguchi; Takao Ohgane; Yasuo Irie; Satoji Takahashi

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