Yoshiki Shimizu
Osaka University
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Featured researches published by Yoshiki Shimizu.
Current Eye Research | 1981
Masakatsu Fukuda; Yasuaki Kuwayama; Sadao Shiosaka; Shinobu Inagaki; Ichiro Ishimoto; Yoshiki Shimizu; Hiroshi Takagi; Masahiro Sakanaka; Kenichi Takatsuki; Emiko Senba; Masaya Tohyama
The distribution of vasoactive intestinal polypeptide (VIP)- and neurotensin (NT)-like immunoreactivities in the chicken retina was investigated by immunohistochemistry. VIP- and NT-positive cells were found throughout the chicken retina. The majority of them were located in the proximal portion of the inner nuclear layer and the processes from these cells directed to the inner plexiform layer where they ramified, suggesting that VIP- and NT-positive cells located in this region probably are amacrine cells.
Neuroscience Letters | 1981
Masakatsu Fukuda; Yasuaki Kuwayama; Sadao Shiosaka; Ichiro Ishimoto; Yoshiki Shimizu; Hiroshi Takagi; Shinobu Inagaki; Masahiro Sakanaka; Emiko Semba; Kenichi Takatsuki; Masaya Tohyama
The distribution of substance P (SP)-like immunoreactivity in the rat retina was investigated by immunohistochemistry. SP-positive cells were found throughout the retina. The majority of them were located in the proximal portion of the inner nuclear layer and the processes from these cells directed to the inner plexiform layer where they ramified, suggesting that SP-positive cells located in this region probably are amacrine cells. Few SP-positive cells were seen within the ganglion cell layer. They were considered displaced amacrine cells.
Brain Research | 1982
Ichiro Ishimoto; Sadao Shiosaka; Yoshiki Shimizu; Yasuaki Kuwayama; Masakatsu Fukuda; Shinobu Inagaki; Hiroshi Takagi; Masahiro Sakanaka; Kenichi Takatsuki; Emiko Senba; Masaya Tohyama
Substance P-like immunoreactivity (SPI) was investigated in the chicken retina by means of the indirect immunofluorescence method with flat-mounts. SPI cells were located mostly in the peripheral retinal regions, while in the central region, none or only a few cells were seen. Based upon their 3-dimensional profiles, SPI cells can be divided into two types: one type belongs to the stratified amacrine cells of the first sublayer and the other to those of the third to fifth sublayer.
Experimental Eye Research | 1982
Masakatsu Fukuda; Ichiro Ishimoto; Yasuaki Kuwayama; Yoshiki Shimizu; Sadao Shiosaka; Hiroshi Takagi; Masaya Tohyama
Abstract The uptake capacity of the retinal neurons for exogenously administered monoamines was examined in the rat. The present study confirmed the presence of 5,6-dihydroxytryptamine (5,6DHT) accumulating retinal neurons in the rat retina and further disclosed that some retinal cells could accumulate exogenously injected noradrenaline (NA). These NA-labeled cells occupied approximately similar positions in the inner nuclear layer to the 5,6DHT-labeled ones, but the two groups of cells were not identical because simultaneous injections of 5,6DHT and NA demonstrated two types of cells, one having yellow and the other showing green fluorescence, respectively. It should be stressed that these two groups of cells are easily distinguishable from well-known dopamine-containing neurons by their sizes and cell locations. The present study further suggested that the NA-accumulating retinal cells might not contain the NA synthesizing enzyme.
Current Eye Research | 1982
Masakatsu Fukuda; Ichiro Ishimoto; Sadao Shiosaka; Yasuaki Kuwayama; Yoshiki Shimizu; Shinobu Inagaki; Masahiro Sakanaka; Hiroshi Takagi; Emiko Senba; Kenichi Takatsuki; K. Umegaki; Masaya Tohyama
The present study demonstrated numerous LH-RH--positive structures in the paddy-bird (padda orizivora) retina. LH-RH-positive cells were seen in the ganglion cell layer (GL), inner plexiform layer (IPL) and inner nuclear layer (INL). Judging from the morphological features, the former two types of cells may belong to the displaced amacrine cells and the latter to the amacrine cells. LH-RH-positive fibers were found in the nerve fiber layer, GL, IPL, INL and outer plexiform layer.
Neuroscience Letters | 1982
Yoshiki Shimizu; Ichiro Ishimoto; Sadao Shiosaka; Yasuaki Kuwayama; Masakatsu Fukuda; Shinobu Inagaki; Masahiro Sakanaka; Masaya Tohyama
Abstract The direct contact between substance P (SP)-containing fibers and pupillary sphincter muscles of the rat was demonstrated at the level of the electron microscope by means of the immunoperoxidase technique. The results suggest a visceromotor function of SP in addition to its presumed sensory function.
The Journal of Comparative Neurology | 1982
T. Nishimoto; Michio Akai; Shinobu Inagaki; Sadao Shiosaka; Yoshiki Shimizu; Kazumi Yamamoto; Emiko Senba; Masahiro Sakanaka; Kenichi Takatsuki; Yoshinobu Hara; Hiroshi Takagi; Takashi Matsuzaki; Yuriko Kawai; Masaya Tohyama
The Journal of Comparative Neurology | 1983
Kazumi Yamamoto; Tomohiro Matsuyama; Sadao Shiosaka; Shinobu Inagaki; Emiko Senba; Yoshiki Shimizu; Ichiro Ishimoto; Tōru Hayakawa; Masayasu Matsumoto; Masaya Tohyama
Acta Histochemica Et Cytochemica | 1981
Ichiro Ishimoto; Masakatsu Fukuda; Yasuaki Kuwayama; Yoshiki Shimizu; Sadao Shiosaka; Shinobu Inagaki; Kenichi Takatsuki; Masahiro Sakanaka; Hiroshi Takagi; Emiko Senba; Masaya Tohyama
Acta Histochemica Et Cytochemica | 1982
Ichiro Ishimoto; Yasuaki Kuwayama; Yoshiki Shimizu; Masakatsu Fukuda