Yoshiro Funakoshi
Takeda Pharmaceutical Company
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Featured researches published by Yoshiro Funakoshi.
Drug Development and Industrial Pharmacy | 1977
Yoshiro Funakoshi; Tatsuo Asogawa; Eiichi Satake
AbstractThe factors affecting the distribution of compacting pressure during the process of dry granulation with a roller compactor, have been elucidated experimentally.Lactose powder was used with incorporation of a small amount of riboflavine as a pressure indicator.The rollers used in this study had been designed as a concavo-convex pair that exactly keep their mutual fit while rotating. The flanges formed by the concavity of the concave roller at its both ends, called “rims” in this paper, were subjected to several experimental variations in the angles of wall siopes, namely, 45°, 65°, 75°, and 90°.These inclined gripping walls acted as compensators, cancelling the resistance in the powder flow due to the side seals attached to both ends of the rollers.The overall effect was that the pressure of compaction was adjusted uniformly over the whole width of the rollers, and the best result was obtained at a rim angle of 65°.In this experiment, however, a rectangular-aperture chute, when equipped at the del...
Powder Technology | 1980
Yoshiro Funakoshi; Masaki Yamamoto; Yoshihiko Matsumura; Hiromu Komeda
Abstract Necessary conditions were studied for the optimum operation of agglomeration granulation. The mechanisms that would realize these conditions were investigated by several experiments. On the basis of the results obtained, a novel granulating system involving a surface wetness control mechanism has been developed. The present paper describes the mixing and dispersing characteristics of the coating vessel, the detection method for wetness control, the particular spraying units, and the operating conditions thereof, together with the characteristics of this newly developed powder coating granulation system. This system has been shown to provide an easy and reproducible granulating technique even when products below 1 mm in size are required.
Archive | 1969
Kiyoshi Fujii; Yoshiro Funakoshi; Takehiko Kajiura; Toshihiko Kanamaru; Hiromu Komeda; Masaki Nishitani
Archive | 1970
Asogawa T; Yoshiro Funakoshi; Matsumura Y; Satani E; Wada S
Archive | 1976
Yoshiro Funakoshi; Tatsuo Asogawa; Eiichi Satake; Shimesu Motoyama; Shuri Yamada; Morio Kakukawa
Journal of The Society of Materials Science, Japan | 1969
Yoshiro Funakoshi; Takehiko Kajiura; Tatsuo Asogawa
Archive | 1976
Yoshiro Funakoshi; Tatsuo Asogawa; Eiichi Satake; Shimesu Motoyama; Shuri Yamada; Morio Kakukawa
Archive | 1973
Yoshiro Funakoshi; Yoshihiko Matsumura; Masaki Yamamoto; Hiromu Komeda
Archive | 1970
Yoshiro Funakoshi; Hiromi Nakatani; Tatsuo Asogawa; Takehiko Kajiura
Archive | 1969
Yoshiro Funakoshi; Toshihiko Kanamaru; Takehiko Kajiura; Kiyoshi Fujii; Masaki Nishitani; Hiromu Komeda