Yoshitada Imai

Bilateral testicular tumors: A report of nine cases with long-term follow-up

Background : The incidence and clinical features of bilateral germ cell testicular tumor (GCTT) in the Japanese population are not fully characterized. We examined the incidence, clinical features, management and outcome, sexual status, hormonal environment, implication of androgen replacement, and human leukocyte antigen (HLA) typing of bilateral GCTT.

Surveillance study for clinical stage I testicular seminomas and nonseminomatous germ cell tumors.

Background: Optimal therapy for stage I testicular tumors is still controversial. This study evaluated the efficacy of a surveillance policy for patients with testicular stage I seminomas and nonseminomatous germ cell tumors (NSGCT).

Intrascrotal Epidermoid Cyst: Report of Two Cases

A 70‐year‐old man and a 52‐year‐old man each presented with a painless extratesticular, intrascrotal mass. Magnetic resonance imaging revealed a cystic mass and was the most useful modality for the diagnosis. Complete excisions were performed, and the lesions were histologically diagnosed as epidermoid cysts. Intrascrotal, extratesticular epidermoid cysts are uncommon lesions believed to be teratomas or the result of abnormal embryological closure of the median raphe. However, it is difficult to explain the etiology of some masses by either of these mechanisms.

Feulgen-Deoxyribonucleic Acid Values in the Cytology of Bladder Cancer

The deoxyribonucleic acid values of cells separated from fixed specimens from patients with bladder cancer were determined with the use of a microspectrophotometer and were compared to the grade and stage of cancer tissues. A histogram of nuclear deoxyribonucleic acid values showed flatness of the mode, deviation of the stem line to the right and an increase of polyploid cells associated with an increase in the grade and stage of cancer. Prognosis seems to be related more closely to deoxyribonucleic acid values off cancer tissues than to the stage and grade of cancer. Deoxyribonucleic acid values of exfoliated cells from fresh cancer tissue and the cells in the urine of the same patients were compared, revealing similar patterns. Indication of grade could be made in some cases by determining nuclear deoxyribonucleic acid values of exfoliated cells in urine. This result indicates that determination of nuclear deoxyribonucleic acid values is a valuable parameter for automated evaluation of urinary cytology.