Youngran Yang

Are Local Public Health Department Services Related to Racial Disparities in Mortality

Our study aim was to determine whether local health department (LHD) services were associated with U.S. racial disparities in 1993-to-2005 mortality rates. In a national sample of LHDs, we examined 10 LHD service domains and gaps in Black–White all-cause mortality rates, drawing data from the National Association of County and City Health Officials’ National Profile of Local Health Departments surveys, as well as mortality and other public data files. Two service domains, maternal/child health and other activities, were significantly associated with decreases in the Black–White mortality gap for 15- to 44-year-olds. The health services domain approached significance in decreasing this gap. Screening was associated unexpectedly with a significant increase in the Black–White mortality gap for 15- to 44-year-olds. Selected LHD services that are provided directly to individuals and are allocated by need may have particular benefit for reducing Black–White mortality disparities for U.S. adults aged 15 to 44.

Becoming a person with HIV: experiences of Cambodian women infected by their spouses

Abstract We conducted an interpretive phenomenological investigation in order to understand, within a Cambodian sociocultural context, the lived experiences of women infected with HIV by their husbands as they navigated the tasks of discovering, disclosing and dealing with the diagnosis. Using an open-ended interview protocol and an interpretive phenomenological approach, data were analysed from 15 women (aged 28–42 years) who self-identified the HIV transmission as coming from their spouses. Using qualitative inductive analysis, we were able to identify three main themes: (1) finding oneself to be HIV-positive, (2) encountering HIV – accepting an unwelcomed guest and (3) going public – dealing with the fear of discrimination. Participants consistently delayed testing for HIV and, after receiving an HIV-positive diagnosis, had to deal with painful emotions and discrimination within their social network. The complexity of gender roles and the sociocultural status of the women acted as behavioural determinants of their responses to HIV transmission from their spouses.

Recognizing global disparities in health and in health transitions in the 21st century: what can nurses do?

PURPOSE To examine changes in patterns of health and disease in global context between rich countries (USA, Korea, South Africa) and poor countries (Cambodia, Malawi) by using the framework of epidemiology theory developed by Orman (1971, 2005), and to raise awareness of global health disparities thereby prompting actions to reduce such disparities. FINDINGS 1) Life expectancy has increased across all selected countries except South Africa; 2) Korea and the USA have substantially lower mortality rates than other countries; 3) Infant and maternal mortality are still high in the poor countries; 4) The major cause of mortality in the poor countries is still communicable disease with evidence of the onset of non-communicable disease; and 5) The health transition theory provides a description and explanation of the differences in progress in economic development between countries but fails to explain differences in health status within and between countries. CONCLUSIONS Life expectancy and mortality are enormously different among the five selected countries. This excessive health disparity is primarily due to the higher risk of communicable diseases in low-income countries. Social determinants of health are mainly responsible for the health disparities observed within and between countries. CLINICAL RELEVANCE Future health care development and global research priorities will not be the same for all countries because the pattern of health transitions in the developing countries is not the same as the developed countries. Actions to reduce global health disparities need to recognize the conditions and social context in which persons live. An effective strategic approach to global health equality should develop a shared system of values, priorities, and delivery infrastructures with the populations who are targeted, aligning delivery within the local social contexts.

Relationship between expression level of hygromycin B resistant gene and Agrobacterium tumefaciens-mediated transformation efficiency in Beauveria bassiana JEF-007.

Agrobacterium tumefaciens‐mediated transformation (AtMT) is an effective method for generation of entomopathogenic Beauveria bassiana transformants. However, some strains grow on the selective medium containing hygromycin B (HygB), which reduces the selection efficiency of the putative transformants. In this work, a relationship between HygB resistance gene promoter and AtMT efficiency was investigated to improve the transformant selection.

An evaluation of quality of life among Cambodian adults living with HIV/AIDS and using antiretroviral therapy: a short report

ABSTRACT The aim of this study was to evaluate quality of life (QOL) and analyze its determinants among Cambodian adults living with HIV/AIDS who are on antiretroviral therapy (ART). A cross-sectional study was conducted using convenience sampling to select 150 adults 18 years of age or older from the patient population at the HIV/AIDS care hospital in Phnom Penh, Cambodia. QOL was assessed using the World Health Organization Quality of Life HIV BREF; socio-demographic characteristics, time elapsed since HIV diagnosis, months on ART, CD4 cell count, family and community support, depression, and anxiety were included in the survey. Results of the multiple regression analysis indicate that positive predictors of QOL included being female, being less 40 years old, having a household monthly income greater than 300 USD, having an education beyond the secondary level, or being employed. However, time elapsed since HIV diagnosis and duration of ART were not significantly associated with QOL and CD4 cell count and the World Health Organization clinical stage had little association with QOL. Perceiving oneself as healthy and happy and reporting no depression or anxiety were associated with a positive QOL. These findings suggest the importance of group-specific interventions to improve the QOL for those people living with HIV/AIDS in Cambodia who are male, have a low household income or education level, are unemployed, or are anxious or depressed.

State of the Science: The Efficacy of a Multicomponent Intervention for ART Adherence Among People Living With HIV

&NA; Incorrect or inconsistent adherence to antiretroviral therapy (ART) compromises the effectiveness of medications and the patient’s chances of achieving viral suppression; near‐perfect (>95%) compliance is required for both immediate and long‐term clinical success. This report presents a systematic review of a multicomponent intervention to address adherence to ART and explores whether this intervention, when compared with standard care, resulted in improved ART adherence. Eleven randomized controlled trial studies published between 1999 and 2008 were reviewed. Seven of these demonstrated a beneficial effect from multicomponent intervention, which primarily incorporated individual education and one to three additional interventions. Interventions targeting the improvement of the patients medication management skills were particularly successful. However, because of incongruent results across studies, it could not be determined whether improved adherence extended to improved virologic or immunologic outcomes. There is a need for standardization and increased methodological rigor in the execution of adherence trials.

“I Am a Good Example”: Suggestions From HIV-Infected Cambodians for Preventing HIV Infection in Marital Relationships

&NA; Developing effective and influential messages for HIV prevention in marriage has been difficult. We explored couple‐based HIV prevention measures that would be socially and culturally suitable for Cambodia. Thirty in‐depth qualitative interviews were conducted with people living with HIV in the local Khmer language. Using thematic analysis, codes and themes were generated to get to the meanings of participant data. Male and female suggestions were analyzed together, and four themes emerged: (a) Safer practices, (b) Trustworthy relationships, (c) Sexual variety, and (d) Exemplar. Premarital HIV testing, grooming oneself, sexual variety within a married relationship, monogamy, and sex education for teenagers were significant suggestions derived from participant input about protecting spouses from HIV infection. The explained strategies illustrated the importance of gender‐based prevention programs in Cambodia and provided insight about needed and possible interventions to prevent HIV transmission within marriage.

A cultural and contextual analysis of health concepts and needs of women in a rural district of Nepal

Introduction: Globally, individuals and groups have different notions of health promotion influenced by their social and cultural contexts. Effective primary health care and healthy public policy depend on a clear understanding of people’s perceptions of health and their health needs. Women in the Far Western Region (FWR) of Nepal live in one of the most remote and rural areas in that country, and their general health status is one of the worst in that country. In this study we explored the socio-cultural health concepts and needs of women in a district of Nepal’s FWR. Methods: Qualitative research methods and a culture-centred approach guided the study, with 30 women from the district of Dadeldhura in the FWR participating in in-depth interviews. Data were analysed through qualitative content analysis. Results: The women’s concepts of health included ‘absence of disease’, ‘no tension’, ‘peace in the family’ and ‘being able to work’. The participants felt good health required good food, wealth, education and employment for their children, and a healthy community (free of drug or alcohol addiction). ‘Money is everything’ also emerged as a main theme, linking the concept of wealth to good health. To improve health, respondents recommended that the government provide financial support for education and employment and a focus on listening to and caring for the country’s rural poor. Conclusions: Overall, participants’ perceived health as not just about themselves but their families and communities. Socially as well as culturally determined gender roles influenced the health concepts and needs of the women. This study’s findings can be used to guide public health leaders in priority-setting and in determining strategies for women’s health promotion in rural districts of Nepal and other similar cultures.

Experiences, Emotions, and Adjustments of HIV-Infected Men in HIV-Concordant Marital Relationship in Cambodia

Although it has been well documented that the HIV infection experience can be problematic for those affected, the experiences and perceptions of living with HIV among married males in Cambodia have not yet been examined until now. This study’s purpose was to describe the revelations, emotions, reactions, and adjustments to HIV diagnosis among infected Cambodian males in seroconcordant heterosexual relationship. Fifteen qualitative in-depth interviews were conducted with 15 HIV-positive males using unstructured, open-ended questions and in the local Khmer language. Conventional content analysis method was employed for analyzing data. After analysis, four main categories were developed: knowledge of HIV-positive status; realization of self-deeds; discouraging news for both partners; and comparative improvement of life. Participants reported the appearance of physical symptoms as the only reason for pursuing HIV testing. Feelings ranged from sadness and guilt to acceptance of HIV infection in their lives. The participants’ wives expressed anger and worry about being infected by their husbands. However, sufficient inspiration from medical personnel and peer groups, as well as a shared concern for their children, helped couples adjust to their dyadic relationship. The study results highlight the link between individual and couple experiences and emotions post-infection, with implications for designing and implementing coping interventions for this population. The findings of this study have public health implications in the design of couple-based intervention and counseling programs for HIV prevention and treatment with the input of the HIV-positive individuals’ voices.

성인 초기의 아토피피부염이 자살생각, 자살계획 및 자살시도에 미치는 영향

Purpose: This study aims to investigate the effects of atopic dermatitis on suicidal ideation, plans and attempts in young adult. Methods: Data are from the Sixth Korean National Health and Nutrition Examination Survey (KNHANES VI, 2013, 2015) in a sample of 2,983 respondents aged 19 to 39 years. Data were analyzed using Frequency, Percentage, x test, Complex sample multivariate binary logistic regression analysis with SPSS version 18.0 software. Results: Firstly, factors affecting suicidal ideation are gender, education level, smoking, self-reported health status, asthma, depression and stress perception. Factors affecting suicidal plan are education level, self-reported health status, asthma and depression. Lastly, factors affecting suicidal attempt are gender, education level, smoking, self-reported health status, depression and stress perception. Compared to non-atopic group, the prevalence of suicidal ideation and plan of atopic group increased from odds ratio 2.14 to 2.48 and 1.90 to 2.50, respectively. Odds ratio for suicidal attempt was odds ratio 2.69 (10% error level). Conclusion: The results show that atopic dermatitis in young adult affects suicidal ideation, plans and attempts. Therefore, it is necessary to identify atopic patients who have suicidal thoughts and plans and develop an intervention program to prevent and manage suicide in young adult.