Yu-Bo Wang

New sesquiterpene and phenolic glucosides from Saussurea involucrata

One new guaiane-type sesquiterpene glucoside (1) and one new phenolic glucoside (2) were isolated from the whole herb of Saussurea involucrata. Their structures were established by spectroscopic methods, mainly 1D and 2D NMR, and mass spectral analysis.

Diterpenoids from Euphorbia esula

Abstract Aim To study the chemical constituents of the aerial parts of Euphorbia esula . Methods Compounds were isolated by repeated column chromatography over silica gel and Sephadex LH-20. Structures were elucidated based on spectral analysis and comparison with literatures. Results Three ingenane-type diterpenoids were isolated and identified as 16-benzoyloxy- 20-deoxyingenol 5-benzoate ( 1 ), ingenol-3, 20-dibenzoate ( 2 ) and 13, 16-dibenzoyloxy-20-deoxyingeno-3-benzoate ( 3 ), respectively. Conclusion Compound 1 is a new ingenane-type diterpenoid diester, and compound 3 was isolated from the plant for the first time. In vitro bioassay data showed that diterpenoids 2 and 3 exhibited weak cytotoxicity against Namalwa cells.