Yu. I. Prylutskyy

Anti‐oxidant Properties of C60 Fullerenes in vitro

C60 fullerenes at concentration 10−5 M show a protective effect on apoptotic H2O2–treated thymocytes, restoring the level of GSH in cytoplasm and increasing the activity of electron‐transport chain in mitochondria. The protective of C60 fullerenes most probably results from it ability to incorporate into cell membrane and to prevent lipid peroxidation.

Structural Features of Highly Stable Reproducible C60 Fullerene Aqueous Colloid Solution Probed by Various Techniques

The method of preparation of highly stable reproducible C60 fullerene aqueous colloid solution is described. The structural organization of C60 fullerenes in aqueous solution was studied and analyzed in detail using various techniques such as chemical analysis, UV/VIS spectroscopy, atomic force and scanning tunneling microscopy, dynamic light scattering, and zeta potential methods.

Using water-soluble C60 fullerenes in anticancer therapy

Growth experiments of transplanted malignant tumors in the presence of water-soluble C60 fullerenes were performed on groups of mice. It was found that C60 fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C60 fullerenes in anticancer therapy.

Structure and Thermophysical Properties of Fullerene C60 Aqueous Solutions

The structure and thermophysical properties of fullerene C60aqueous solutions were investigated both experimentally and theoretically. The aggregation kinetics results indicated that the structure of fullerene C60aggregates in water could be described as a fractal system. The IR and electronic absorption spectra obtained confirm the presence of the crystalline phase in aqueous solution. The numerical values of thermodynamic coefficientsαP,βT,βS,cP, andcV, and sound velocity were determined from the measured (P–V–T) data. The vibrational spectrum of the crystalline structure (Thsymmetry group) formed from the hydrated single fullerene C60molecules in aqueous solutions was calculated using the molecular dynamics approach.

Biological Effects of C60 Fullerenes in vitro and in a Model System

With the use of artificial lipid membranes, it is shown that C60 fullerenes are capable to penetrate into a lipid bilayer, by locally strengthening its conductivity. C60 fullerenes under the UV/VIS and X-ray irradiation do not influence the MTT reduction and the DNA structure in thymocytes. UV/VIS irradiated C60 fullerenes give rise to the DNA fragmentation and a decrease of the viability of ascitic Erlich carcinoma cells.

Self-organization C60 nanoparticles in toluene solution

The structure of fullerene C60 in toluene solution was investigated both experimentally and theoretically in detail. C60 was found to aggregate slowly even in fairly dilute solution concentrations ranging from 0.18 to 0.78 g/l at room temperature. The electronic absorption spectra obtained testify to the mainly molecular character of absorption. The aggregation kinetics results indicated that the structure of C60 aggregates could be described as a fractal system. The numerical calculations predicted the formation of stable fullerene (C60)N clusters in toluene solution with sizes >1.2 nm and aggregation number N≥3.

Biophysical studies of fullerene-based composite for bio-nanotechnology

Abstract The UV absorption and fluorescence spectra of biological samples and the DNA structural state in cells under X-ray irradiation in the presence of the fullerene-containing composite, synthesized on the basis of aminopropylaerosil, were investigated and analysed in detail. The significant pro-oxidant effect of the fullerene-containing composite at the low concentration of fullerene C60 (10−5 M) was revealed.

Transport Properties of Composites with Carbon Nanotube‐Based Composites

Abstract The comparative investigation of structure, morphology, and transport properties of nanoscaled carbon materials (NCM) synthesized by different methods is carried out.

Effects of nitrogen-doping configurations with vacancies on conductivity in graphene

Abstract We investigate electronic transport in the nitrogen-doped graphene containing different configurations of point defects: singly or doubly substituting N atoms and nitrogen–vacancy complexes. The results are numerically obtained using the quantum-mechanical Kubo–Greenwood formalism. Nitrogen substitutions in graphene lattice are modelled by the scattering potential adopted from the independent self-consistent ab initio calculations. Variety of quantitative and qualitative changes in the conductivity behaviour are revealed for both graphite- and pyridine-type N defects in graphene. For the most common graphite-like configurations in the N-doped graphene, we also consider cases of correlation and ordering of substitutional N atoms. The conductivity is found to be enhanced up to several times for correlated N dopants and tens times for ordered ones as compared to the cases of their random distributions. The presence of vacancies in the complex defects as well as ordering of N dopants suppresses the electron–hole asymmetry of the conductivity in graphene.

Structure–electrical resistivity relationship of N-doped multi-walled carbon nanotubes

Nitrogen-doped multi-walled carbon nanotubes (N-MWCNT) were synthesized by means of catalytic chemical vapor deposition technique using acetonitrile as carbon source material and ferrocene as catalyst. The structure of the synthesized N-MWCNT was characterized by means of microscopic (SEM, HRTEM) as well as spectroscopic (FTIR, Raman) techniques. Furthermore, the specific resistivity and the electrochemical properties of N-MWCNT were investigated and compared with those of pristine MWCNT. The results are discussed in terms of structural differences between pristine MWCNT and N-MWCNT.