Yu-Qing Cao

A Practical Knoevenagel Condensation Catalyzed by PEG400 and Anhydrous K2CO3 Without Solvent

Abstract Knoevenagel condensation of aromatic aldehydes with active methylene compounds under solvent‐free conditions to synthesize arylidene compounds in good to excellent yields using powdered anhydrous K2CO3 and PEG400 as catalysts has been described.

Aldol condensations catalyzed by PEG400 and anhydrous K2CO3 without solvent

Abstract Aldol condensations of aromatic aldehydes with ketones under solvent‐free conditions to synthesize α,β‐unsaturated ketones in good to excellent yields using PEG400 and powdered anhydrous K2CO3 as catalysts at 90 °C and 120 °C are described.

Facile Preparation of Aryl Sulfides Catalyzed by PEG400 and Nickel without Solvent

Abstract A variety of aryl sulfides were synthesized by aryl bromides with thiols, with PEG400 and nickel as catalysts under basic conditions in the absence of solvents. This article reported an easy and convenient method for formation of aryl‐sulfur bonds.

Etherification of Phenols Catalysed by Solid-Liquid Phase Transfer Catalyst PEG400 without Solvent

Abstract Aromatic ethers were synthesised in excellent yields(above 86 %) and purity by the etherification of phenols with dimethyl sulfate or alkyl halides, catalysed by phase transfer catalyst PEG400 under solvent-free conditions, and the effects of some key reaction conditions were also studied.

A Novel Heterogeneous Synthesis of Acyl Cyanides Catalyzed by PEG400 and Zinc Iodide

Abstract Aroyl cyanides were readily synthesized in moderate yields by the cyanation of aroyl chlorides with dry powdered potassium cyanide under the catalysis of PEG400 and zinc iodide in dichloromethane at room temperature. A preliminary study on the one‐pot preparation of acetyl cyanide was also reported.

CYANIDATION OF HALOGEN COMPOUNDS AND ESTERS CATALYZED BY PEG400 WITHOUT SOLVENT

Primary aliphatic and aromatic nitriles were synthesized in excellent yields (84–96%) and purity by the cyanidation of halogen compounds and esters with dry powdered sodium cyanide catalysed by phase transfer catalyst PEG400 under solvent-free conditions.

Practical Preparation of Esters and Thioacetates from Alkyl Halides and Carboxylates or Thioacetate Catalyzed by PEG400 without Solvent

Abstract Carboxylic esters and thioacetates were conveniently prepared in good to excellent yields under mild conditions by the reaction of alkyl halides with sodium carboxylates or sodium thioacetate catalyzed by PEG400 in the absence of solvents.

A study on the heterogeneous reaction of trialkylsilyl chlorides with inorganic salts and monocarboxylates catalysed by PEG400

The important and useful trialkylsilyl pseudohalides R3SiX, where X=NCS, NCO, N3 or CN and R=methyl or ethyl, and trimethylsilyl monocarboxylates, where X=RCOO, were readily prepared in high yields by nucleophilic substitution of R3SiCl with X ions provided by NaX or KX at room temperature catalysed by PEG400 and zinc iodide. The reactions of trimethylsilyl chloride with some metal oxysalts were also studied for the first time.

A facile and practical method for the preparation of thioacetates from alkyl halides and sodium thioacetate catalysed by PEG400

Thioacetates are conveniently prepared in high yields under mild conditions by the reaction of alkyl halides and sodium thioacetate, prepared in situ from thioacetic acid and sodium carbonate, catalysed by PEG400 at room temperature.

A practical and improved method for the preparation of trimethylsilyl cyanide catalysed by PEG400 and zinc iodide

The useful synthetic reagent trimethylsilyl cyanide was readily prepared in high yield by the cyanation of trimethylchlorosilane with potassium cyanide in the presence of PEG400 and zinc iodide under stirring at room temperature or ultrasonic radiation.