Yu-Xia Da

SYNTHESIS OF 2-(5-(2-CHLOROPHENYL)-2-FUROYLAMIDO)-5-ARYLOXYMETHYL-1,3,4-THIADIAZOLES UNDER MICROWAVE IRRADIATION

2-(5-(2-chlorophenyl)-2-furoylamido)-5-aryloxymethyl-1,3,4-thiadiazoles (IIa–j) are synthesized under microwave irradiation via the cyclization of 1-aryloxyacetyl-4-(5-(2-chlorophenyl)-2-furoyl)-thiosemicarbazides (Ia–j) in the presence of glacial acetic acid.

Conversion of carbohydrates into 5-hydroxymethylfurfural using polymer bound sulfonic acids as efficient and recyclable catalysts

52–94% yields of 5-hydroxymethylfurfural (HMF) from carbohydrates such as monosaccharides, disaccharides and polysaccharides were achieved using PEG-OSO3H or PS-PEG-OSO3H as reusable catalysts in a DMSO/H2O reaction system. Using polymer-supported catalysis, corn stover could also be effectively transformed into HMF and furfural.

Phase Transfer Catalyzed Syntheses of 4-Carboxylphenoxyacetic Acid Derivatives

Abstract A series of new aryl 4-carboaryloxyphenoxyacetates (3a-e) and 4-carboanilinophenoxyacetanilides (3f-s) are synthesized by the reactions of 4-chloroformylphenoxyacetyl chloride with substituted phenols or aromatic amines via liquid-liquid phase transfer catalysis using PEG-400 as the catalyst.

SYNTHESIS OF 2-(4-CHLOROBENZOYLAMIDO)-5-ARYLOXYMETHYL-1,3,4-OXADIAZOLES UNDER MICROWAVE IRRADIATION

2-(4-Chlorobenzoylamido)-5-aryloxymethyl-1,3,4-oxadiazoles (IIa–j) are synthesized by cyclization of 1-aryloxyacetyl-4-(4- chlorobenzoyl)-thiosemicarbazides (Ia-j) in the presence of mercuric acetate under the condition of microwave irradiation.

A Facile Method to 1,4-Diacyl Semicarbazides: Syntheses of 1-Aryloxyacetyl-4-(4-Chlorobenzoyl)-Thiosemicarbazides and Semicarbazides

Abstract A facile method to diacyl semicarbazides is described. Reactions of 4-chlorobenzoyl chloride with ammonium thiocyanate first, then with aryloxyacetic acid hydrazides under phase transfer catalysis give 1-aryloxyacetyl-4-(4-chlorobenzoyl)-thiosemicarbazides (Ia-h). Compounds Ia-h on treatment with potassium iodate under reflux result in the formation of 1-aryloxyacetyl-4-(4-chlorobenzoyl)-semicarbazides (IIa-h) in excellent yields.

Dehydration of biomass to furfural catalyzed by reusable polymer bound sulfonic acid (PEG-OSO3H) in ionic liquid

Polymer bound sulfonic acid (PEG-OSO3H) is active for the dehydration of biomass to furfural. The furfural yield is improved when MnCl2 is added to the reaction mixture. The catalyst was mild, non-volatile, and non-corrosive and can be recycled multiple times (>10) without an intermediate regeneration step and no significant leaching of –OSO3H groups is observed.

SYNTHESIS OF 1-ARYLOXYACETYL-4- (5-(4-CHLOROPHENYL)-2-FUROYL)- SEMICARBAZIDES

Asim ple and efficient route to 1,4-diacyl semicarbazides is described. 1-Aryloxyacetyl-4-(5-(4-chlorophenyl)-2-furoyl)- thiosemicarbazides (Ia–i) on treatment with potassium iodate in the aqueous solution afford 1-aryloxyacetyl-4-(5- (4-chlorophenyl)-2-furoyl)-semicarbazides (IIa–i) in excellent yields.

SYNTHESES OF 1-ARYLOXYACETYL-4-(3-TOLYLOXYACETYL) THIOSEMICARBAZIDES VIA SOLID-LIQUID PHASE TRANSFER CATALYSIS

Abstract A series of new 1-aryloxyacetyl-4-(3-tolyloxyacetyl) thiosemicarbazides is synthesized under the condition of soid-liquid phase transfer catalysis.

SYNTHESIS OF 2-(4-TOLYLOXYACETYLAMIDO)-5-ARYLOXYMETHYL-1,3,4-THIADIAZOLES UNDER MICROWAVE IRRADIATION

2-(4-Tolyloxyacetylamido)-5-aryloxymethyl-1,3,4-thiadia-zoles (IIa–j) are synthesized under microwave irradiation by the cyclization of 1-aryloxyacetyl-4-(4-tolyloxyacetyl)-thiosemicar- bazides (Ia–j) in the presence of glacial acetic acid.

Synthesis of stilbene derivatives via visible-light-induced cross-coupling of aryl diazonium salts with nitroalkenes using –NO2 as a leaving group

The straightforward visible-light-induced synthesis of stilbene compounds via the cross-coupling of nitroalkenes and diazonium tetrafluoroborates under transition-metal-free conditions is described. The protocol uses green LEDs as light sources and eosin Y as an organophotoredox catalyst. Broad substrate scope and exclusive selectivity for the (E)-configuration of stilbenes are observed. This protocol proceeds via a radical pathway, with nitroalkenes serving as the radical acceptor, and the nitro group is cleaved during the process.