Yu Yongtao
Kunming University of Science and Technology
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Publication
Featured researches published by Yu Yongtao.
Environmental Toxicology and Pharmacology | 2017
Zhu Junbo; Yu Yongtao; Li Hongbo; Zheng Fenshuang; Lin Ruyun; Yang Chun’ai
OBJECTIVE This study explored the effects of sucralfate intervention as a novel treatment for paraquat (PQ) poisoning in Sprague-Dawley (SD) rats. METHODS After PQ poisoning, the SD rats were randomly divided into the PQ control group (treated with normal saline), the sodium bicarbonate (SB) treatment group, and the sucralfate (LTL) treatment group. Then, the rats were administered normal saline, sodium bicarbonate solution, or sucralfate suspension as an intervention by gastric lavage. At 1, 3, 6, and 10days after poisoning, the left lungs of some rats were removed to determine the lung wet/dry (W/D) weight ratio. Additionally, the serum cytokine levels were measured, and the lung and kidney tissues were pathologically examined. RESULTS After treatment, the signs and symptoms of the rats were improved, the mortality rate was reduced, the W/D weight ratio of the lung was lower, the cytokine levels [transforming growth factor (TGF)-β1, interleukin (IL)-10, and tumor necrosis factor (TNF)-α] were decreased, and the pathological injuries of the lungs and kidneys were improved. Moreover, sucralfate was significantly more effective than the control (normal saline) group and the SB treatment group. CONCLUSION The results showed that early gastrointestinal lavage with sucralfate effectively reduced the inflammatory response and lung and kidney injuries and improved the survival of the SD rats.
Archive | 2014
Qu Guangfei; Li Junyan; Ning Ping; Ma Yixing; Yu Yongtao
Journal of The Electrochemical Society | 2015
Yu Yongtao; NingPing; Qu Guangfei; Li Junyan; Zhao Qian
Archive | 2014
Qu Guangfei; Zhang Jian; Lin Yilu; Li Junyan; Yu Yongtao; Ning Ping
Archive | 2017
Qu Guangfei; Yu Yongtao; Che Lulu; Li Junyan; Xie Ruosong; Lin Yilong; Cai Shanshan
Archive | 2016
Ning Ping; Ma Yixing; Qu Guangfei; Li Junyan; Yu Yongtao; Xu Ke; Lin Yilong
Archive | 2015
Ning Ping; Yu Yongtao; Qu Guangfei; Li Junyan
Archive | 2015
Ning Ping; Ma Yixing; Wang Xueqian; Qu Guangfei; Xu Ke; Wang Fei; Li Junyan; Yu Yongtao; Wang Langlang
Archive | 2015
Qu Guangfei; Tu Can; Li Junyan; Ning Ping; Yu Yongtao
Archive | 2014
Qu Guangfei; Xie Ruosong; Li Junyan; Yu Yongtao; Ning Ping