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Dive into the research topics where Yuichi Sakano is active.

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Featured researches published by Yuichi Sakano.


The Journal of Antibiotics | 2005

Revised Structures of Epohelmins A and B Isolated as Lanosterol Synthase Inhibitors from a Fungal Strain FKI-0929

Masaaki Shibuya; Barry B. Snider; Yuichi Sakano; Hiroshi Tomoda; Satoshi Omura; Yutaka Ebizuka

The structures of epohelmins A and B isolated as lanosterol synthase inhibitors from a fungal strain FKI-0929 were revised to be 1α-hydroxy-3α-(4′-oxoundec-(5′E)-enyl)-pyrrolizidine and 1β-hydroxy-3α-(4′-oxoundec-(5′E)-enyl)-pyrrolizidine, respectively, by comparison with spectral data of synthetic compounds.


Journal of Asian Natural Products Research | 2004

Flavonoids from the seeds of sphaerophysa salsula

Zhongjun Ma; Isao Fujii; Yutaka Ebizuka; Xian Li; Shigeki Shimomaki; Yuichi Sakano

Two new flavonoids, named sphaerophyside SA and sphaerophyside SB, together with 15 known flavonoids were isolated from the ethanolic extract of the seeds of Sphaerophysa salsula (Pall.) DC. The structures of the new compounds were elucidated mainly on the basis of the 1D and 2D NMR data.


Journal of Biochemistry | 2006

Identification and characterization of carbohydrate molecules in mammalian cells recognized by dengue virus type 2.

Chie Aoki; Kazuya I.-P. Jwa Hidari; Saki Itonori; Akihiro Yamada; Naonori Takahashi; Takeshi Kasama; Futoshi Hasebe; Ma Islam; Ken Hatano; Koji Matsuoka; Takao Taki; Chao-Tan Guo; Tadanobu Takahashi; Yuichi Sakano; Takashi Suzuki; Daisei Miyamoto; Mutsumi Sugita; Daiyo Terunuma; Koichi Morita; Yasuo Suzuki


Biological & Pharmaceutical Bulletin | 2008

Clarithromycin inhibits progeny virus production from human influenza virus-infected host cells.

Daisei Miyamoto; Sayaka Hasegawa; Nongluk Sriwilaijaroen; Sangchai Yingsakmongkon; Hiroaki Hiramatsu; Tadanobu Takahashi; Kazuya I.-P. Jwa Hidari; Chao-Tan Guo; Yuichi Sakano; Takashi Suzuki; Yasuo Suzuki


Phytochemistry | 2004

Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.)☆

Yuichi Sakano; Yukio Okada; Akiko Matsunaga; Takaharu Suwama; Takafumi Kaneko; Kazutoshi Ito; Hiroshi Noguchi; Ikuro Abe


Bioorganic & Medicinal Chemistry Letters | 2005

Synthesis of digalactosyl diacylglycerols and their structure–inhibitory activity on human lanosterol synthase

Rie Tanaka; Yuichi Sakano; Akito Nagatsu; Masaaki Shibuya; Yutaka Ebizuka; Yukihiro Goda


Journal of the American Chemical Society | 2004

Enzymatic cyclization of 22,23-dihydro-2,3-oxidosqualene into Euph-7-en-3β-ol and bacchar-12-en-3β-ol by recombinant β-amyrin synthase

Ikuro Abe; Yuichi Sakano; T. Hideya Tanaka; Weiwei Lou; Hiroshi Noguchi; Masaaki Shibuya; Yutaka Ebizuka


The Journal of Antibiotics | 2004

Epohelmins A and B, novel lanosterol synthase inhibitors from a fungal strain FKI-0929.

Yuichi Sakano; Masaaki Shibuya; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura; Yutaka Ebizuka


Journal of the American Chemical Society | 2004

Mechanism and stereochemistry of enzymatic cyclization of 24, 30-bisnor-2, 3-oxidosqualene by recombinant β-amyrin synthase

Ikuro Abe; Yuichi Sakano; Megumi Sodeyama; Hideya Tanaka; Hiroshi Noguchi; Masaaki Shibuya; Yutaka Ebizuka


Biological & Pharmaceutical Bulletin | 2005

Inhibition of human lanosterol synthase by the constituents of Colocasia esculenta (taro).

Yuichi Sakano; Motoh Mutsuga; Rie Tanaka; Hiroyuki Suganuma; Takahiro Inakuma; Masatake Toyoda; Yukihiro Goda; Masaaki Shibuya; Yutaka Ebizuka

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Rie Tanaka

Nagoya City University

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