Yuji Kakubari

Hemodynamic changes during hemodialysis.

35 patients with chronic renal failure were examined during the first 2 h of hemodialysis by invasive and non-invasive methods. The cardiac output was determined by the dye dilution technique in 11 of these patients and by Swan-Ganz catheterization in 5. In the patients without severe myocardial damage, the cardiac output during hemodialysis showed a significant increase (p less than 0.05), accompanied by a significant decrease of both mean blood pressure (p less than 0.05) and total peripheral resistance (p less than 0.05). Mean pulmonary artery pressure and pulmonary artery wedge pressure were reduced in all cases during hemodialysis. The increase in cardiac output during hemodialysis in patients with chronic renal failure may be attributed to the decrease in afterload.

A Comparison of the Effectiveness of Anisodamine and Norepinephrine on Hemorrhagic Shock in Rabbits

Hemorrhagic shock was experimentally produced in 123 rabbits which were divided into control groups and groups treated separately with anisodamine and norepinephrine. A comparison of their effect on t