Yuka Kawashita

Synthesis of Heteroaromatic Compounds by Oxidative Aromatization Using an Activated Carbon/Molecular Oxygen System

A variety of heteroaromatic compounds, such as substituted pyridines, pyrazoles, indoles, 2-substituted imidazoles, 2-substituted imidazoles, 2-arylbenzazoles and pyrimidin-2(1H)-ones are synthesized by oxidative aromatization using the activated carbon and molecular oxygen system. Mechanistic study focused on the role of activated carbon in the synthesis of 2-arylbenzazoles is also discussed. In the final section, we will disclose the efficient synthesis of substituted 9,10-anthracenes via oxidative aromatization.

Efficient synthesis of substituted indoles and benzazoles by oxidative aromatization using activated carbon-molecular oxygen system

Efficient synthesis of substituted indoles was achieved by oxidative aromatization of indolines using activated carbon-molecular oxygen (O 2 ) system. Benzazoles (benzimidazole and benzothiazoles) were also prepared by the reaction of 1,2-phenylenediamine and 2-aminobenzenethiol with formaldehyde in the presence of activated carbon under oxygen atmosphere.