Yung Khee Chung

Diagnosis of Herniated Tibialis Anterior Muscle by Dynamic Ultrasonography - A Case Report -

증례 보고 현역 군인인 21세 남성이 3일 전 약 10 km 구보를 한 뒤 발생한, 우측이 더 심한 양상을 보이는 양측 하퇴 전방 의 동통을 주소로 내원하였다. 과거력상 환자는 외상의 경력은 없었으며 10년 전부터 오랜 시간 서 있거나 장거 리 보행 및 구보후에 하퇴 전측방으로 동통이 발생한다고 하였으며 가족력은 없었다. 내원 시 시행한 이학적 검사 상 족관절의 배부굴곡 시 양측 하퇴의 중앙, 경골 전연의 외측으로 접하여 작은 연부 종괴가 촉지되었으며 이 종괴 는 족관절의 족저굴곡 시 소실되는 양상을 보였다. 양측 하지의 단순 방사선 촬영 결과 경.비골의 이상 소견은 관찰되지 않았다. 양측 하퇴 전방부에서 근육의 운동 시 크기가 증가하는 양측 하지의 종괴에 대해 우선 양성 연 부 조직 종양과의 감별 진단을 위해 초음파 검사를 시행 하였다. 초음파 소견상 증세가 더 심한 우측 하퇴 중앙의 경골에 접한 외측부에서 족관절의 족저 굴곡 시, 즉 이환 역동적 초음파를 통한 양측성 전경골근 탈출의 진단 증례 보고-

Immunoreactivity of Somatostatin Receptor Subtype 2 in Dorsal Root Ganglia in the Rat

Purpose: Somatostatin has been suggested to play a role in the transmission of neurotransmitters and in the modulation of pain. Of the different subtypes of somatostatin receptors 2, sstr2A and sstr2B are important in the modulation and transmission of pain. The present study was carried out to investigate sstr2 immunoreactivity in rat. Materials and Methods: Dorsal root ganglia (DRG) cells at the levels of the spinal cord of 10 rats (Sprague-Dawley, 200-250 g) were examined for sstr2 by immunohistochemistry. Results: In the control group, sstr2A immunoreactivity was strongly positive in the dense network within laminae I and II of the dorsal horn at spinal levels (). In contrast to sstr2A, sstr2B immunoreactivity was observed throughout laminae III-VI. In the DRG, sstr2A and sstr2B immunoreactivities were mainly found in medium-sized neurons. Conclusion: The distribution of sstr2A immunoreactive cells among sstr2 in the dorsal root ganglia (L4-6) resembles that of somatostatin. Incontrast to sstr2A, sstr2B immunoreactivity showed a different distribution. The presence of sstr2A at laminae I and II, and sstr2B at laminae III-VI of the dorsal horn may modulate sensory functions at these different regions of the spinal cord. Considering different actions according to the receptors of the neurotransmitter, the functions of the isoforms of sstr2 appear variable in terms of modulating and transmitting pain.

Origins of Dorsal Root Ganglion Cells with CGRP innervating Quadriceps Femoris Tendon of Rat

Purpose : This study was undertaken to determine the origins of dorsal root ganglion (DRG) cells containing calcitonin gene-related peptide (CGRP) which innervate the quadriceps femoris tendon in the rat. Materials and Methods : DRG cells containing CGRP, which innervate the quadriceps femoris tendon, from 25 rats (Sprague-Dawley, 200-250 g) were examined using the retrograde tracing technique (neural tracers: horseradish peroxidase and fluorogold) combined with immunohistochemistry. Results : Injection of horseradish peroxidase (HRP) or fluoro-gold (FG) into the quadriceps femoris tendon resulted in the ipsilaterally labelling of cells between L1 and L6 DRGs. However, a large number of the labelled cells innervating the quadriceps femoris tendon were found in the L3 and L4 DRGs. Many DRG cells were immunostained with CGRP antibody in the L1-6 DRGs. The number of CGRP immunoreactive cells in the lumbar DRGs was larger than in the sacral DRG. FG labelled cells containing CGRP immunoreactivity (FG+CGRP cells) were found in the lumbosacral DRGs. Many FG+CGRP cells innervating the quadriceps femoris tendon were located in the L3 and L4 DRGs. Conclusion : These results show that the main DRG origin for the sensory innervation of the quadriceps femoris tendon is L3 or L4. The neurogenic pain of the quadriceps femoris tendon may originate from this region, and suggests that this may be important for the release of neurogenic pain.