Yury V. Fedorov

Surface tension of silver in different media

Abstract By means of electron microscopy, the stability of silver particles in redox buffers has been studied and values of the surface tension of silver in aqueous solution of buffers and a gelatin medium have been determined to be 0.72 J m −2 and 0.68 J m −2 , respectively. Using calculations of the binding energy per atom in vacuum, an effective value of 0.86 J m −2 for the surface tension for silver clusters was determined.

Complexation of Bi3+, Ac3+, Y3+, Lu3+, La3+ and Eu3+ with benzo-diaza-crown ether with carboxylic pendant arms

Abstract Polyaminopolycarboxylates are attractive ligands for binding cationic radionuclides for synthesis of radiopharmaceuticals with target delivery to tumor cells. Nowadays beta emitting Y−90 and Lu−177 are used as therapeutic agents, while Ac−225 and Bi−213 are considered as perspective for alpha therapy. In the present study new data on complexation of Y3+, Lu3+, Ac3+ and Bi3+ with 2,2’-(15-formyl-2,3,5,6,8,9,11,12-octahydrobenzo [b][1,4,10,7,13]trioxadiazacyclopentadecine-4,10- diyl)diacetic acid are presented. For ligand and complexes characterization potentiometric titration, solvent extraction, chromatography and solubility techniques were applied. The highest values of stability constants within the range of log K = 5.8 – 7.5 were found for Ac3+ and REE. Fast complex formation is established which is beneficial for practical applications in radiopharmaceutical synthesis.

Pseudorotaxane Structures Based on Thiophene-Containing Dibenzo-24-crown-8 Ether Derivatives

Разработан метод получения дибензо-24-краун-8-эфиров (ДБ24К8), содержащих один или два 3,4-диоксиэтилентиофеновых заместителя, с помощью реакции кросс-сочетания по Стилле. Исследование комплексообразования монозамещенного ДБ24К8 с виологеном с использованием спектральных и электрохимических методов подтвердило образование псевдоротаксановой структуры. Строение синтезированных соединений доказано с помощью комплекса физико-химических методов.