Yutaro Okuno

Localized Surface Plasmon Resonance Sensor Based on Fabricating Nano-period Structure for High Throughput by Polymer

To realize a low-cost sensor and a sensor chip, we propose a localized surface plasmon resonance (LSPR) sensor in which nano-imprinting technology is applied to produce periodic arrangements of metallic nanostructures; we also verify its utility. LSPR can concentrate electric fields in the vicinity of nano-order metal structures. Accordingly, the sensing depth can be localized, resulting in noise reduction. Furthermore, nano-imprinting can be applied inexpensively and with high accuracy to fabricate nano-patterned sensor chips in large quantities. This work involves the design of an original nano-period structure and the application of nano-imprint technology to the fabrication of a sensor chip. The result is a proposal for a biosensor that allows fabrication with both higher throughput and lower cost.

A Nanobiosensor Fabricated by Nanoimprinting Technology

A new biosensor with a high sensitivity and a low process cost is presented in this paper. Localized surface plasmon resonance generated inside the nanogrooves was verified to have a high sensitivity and this structure could be produced using a nano imprinting technology which realizes a high reproducibility and a mass-production. The present sensor had five times as high sensitivity as the conventional colloidal localized surface plasmon resonance sensor. And the detection of BSA antigen using the present sensor was attained in this research.

Development of Localized Surface Plasmon Resonance Sensor Based on Nanoimprinting Technology

This paper introduces a localized surface plasmon resonance biosensor fabricated by using nanoimprinting technology. The detection of a cancer marker (alpha-fetoprotein) by a desktop proto-model based on this principle is also presented.