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Dive into the research topics where Yuya Sugiyama is active.

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Featured researches published by Yuya Sugiyama.


Journal of Organic Chemistry | 2013

A synthesis of all stereoisomers of tenuecyclamide A employing a fluorous-Fmoc strategy.

Yuya Sugiyama; Fumitaka Eguchi; Atsushi Miyazaki; Koichi Hayashi; Hiroaki Takahashi; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi

A concise liquid-phase combinatorial synthesis of all stereoisomers of Tenuecyclamide A was achieved using a mixture of D-/L-alanine with each stereoisomer encoded by a different f-Fmoc tag. The synthetic strategy using f-Fmoc reagents as the protecting group for amino acids has been demonstrated to be a useful method for diverse polypeptide analogue synthesis.


Tetrahedron | 2012

A fluorous Mukaiyama coupling reagent for a concise condensation reaction: utility of medium-fluorous strategy

Yuya Sugiyama; Yuki Kurata; Yoko Kunda; Atsushi Miyazaki; Junko Matsui; Shuichi Nakamura; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi


Tetrahedron Letters | 2010

Pronounced rate enhancements in condensation reactions attributed to the fluorous tag in modified Mukaiyama reagents

Masato Matsugi; Shuichi Nakamura; Yoko Kunda; Yuya Sugiyama; Takayuki Shioiri


Tetrahedron Letters | 2013

Fluorous mixture synthesis of fluorous-Fmoc reagents using a one-pot double tagging strategy

Yuya Sugiyama; Kazuki Ishihara; Yuka Masuda; Yuki Kobayashi; Hiromi Hamamoto; Masato Matsugi


Tetrahedron Letters | 2015

A medium fluorous Grubbs–Hoveyda 2nd generation catalyst for phase transfer catalysis of ring closing metathesis reactions

Yuki Kobayashi; Sae Inukai; Natsuki Kondo; Tomoko Watanabe; Yuya Sugiyama; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi


Tetrahedron | 2015

Development of efficient processes for multi-gram scale and divergent preparation of fluorous-Fmoc reagents

Yuya Sugiyama; Natsuki Endo; Kazuki Ishihara; Yuki Kobayashi; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi


Synlett | 2016

Highly Activated Second-Generation Grubbs–Hoveyda Catalyst Driven by Intramolecular Steric Strain

Yuki Kobayashi; Hiroki Miyazaki; Sae Inukai; Chika Takagi; Reo Makino; Kento Shimowaki; Rina Igarashi; Yuya Sugiyama; Shuichi Nakamura; Masato Matsugi


European Journal of Organic Chemistry | 2015

Concise Synthesis of All Stereoisomers of Dendroamide A by Fluorous Mixture Synthesis Based on Fluorous‐Fmoc Protection of Amino Acids

Hiroaki Takahashi; Natsuki Endo; Hitomi Takanose; Yuya Sugiyama; Fumitaka Eguchi; Kazuma Oguri; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi


Tetrahedron-asymmetry | 2014

A comparative study of the asymmetric epoxidation of aromatic olefins using the first generation manganese salen epoxidation catalysts and their light fluorous variants: an interesting discovery on the use of benzotrifluoride as a cosolvent

Yuki Kobayashi; Sae Inukai; Naoki Asai; Mami Oyamada; Shohei Ikegawa; Yuya Sugiyama; Hiromi Hamamoto; Takayuki Shioiri; Masato Matsugi


Synthesis | 2017

Grubbs–Hoveyda Second-Generation Catalysts Activated by the Introduction of a Light Fluorous Tag onto the Bidentate Ligands

Yuki Kobayashi; Naoki Suzumura; Yuki Tsuchiya; Machiko Goto; Yuya Sugiyama; Takayuki Shioiri; Masato Matsugi

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Shuichi Nakamura

Nagoya Institute of Technology

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