Yves Catonné

Pelvis and total hip arthroplasty acetabular component orientations in sitting and standing positions: Measurements reproductibility with EOS imaging system versus conventional radiographies

INTRODUCTION The literature has recently underlined the interest of pelvic and acetabular component orientation measurements in the standing and sitting position. Radiographic follow-up of total hip arthroplasty (THA) is based on standard AP and lateral X-rays. The use of EOS™ 2D imaging system reduces patients radiation exposure compared to conventional X-rays. However, using this system, the validity and reproducibility of angular measurements, have not been studied yet for the measurement of pelvic and acetabular parameters in patients with THA. HYPOTHESIS The EOS™ 2D imaging system offers similar advantages to conventional X-rays in the measurement of pelvic and acetabular orientation parameters which are commonly used. PATIENTS AND METHOD Five angular parameters characterizing pelvic tilt and acetabular cup orientation were determined using the same digital measurement Imagika™ software based on two series of standard X-rays and EOS™ 2D images acquired in both standing and sitting positions. Radiographs from 50 patients with unilateral THA were measured three times by two observers. Intra- and interobserver reproducibility using each method was independently studied then paired comparison was performed. RESULTS The ICC and Spearman rank correlation coefficient demonstrated an excellent EOS/conventional X-ray correlation. According to the parameters, the mean difference between these two imaging modalities ranged from 0.30° to 3.43° (P<0.05). The intra- and interobserver variability ranged from ± 2.97° to ± 6.46° using the EOS™ imaging system and from ± 4.26° to ± 10.22° using conventional X-rays (P<0.05). DISCUSSION The EOS™ 2D imaging system may replace conventional X-rays in the assessment and monitoring of pelvic and acetabular cup orientation in THA. LEVEL OF EVIDENCE Level III. Prospective diagnostic study.

Accuracy of the preoperative planning for cementless total hip arthroplasty. A randomised comparison between three-dimensional computerised planning and conventional templating.

INTRODUCTION A high accuracy was recently reported for the three-dimensional (3D) computerised planning of total hip arthroplasty (THA), comparing well with navigation regarding leg length and femoral offset. However, there is no randomised study comparing 3D preoperative planning with conventional 2D templating in terms of accuracy and clinical relevance. HYPOTHESIS The 3D preoperative planning has a higher accuracy than the conventional 2D preoperative templating regarding the implants size and their positioning. PATIENTS AND METHODS A prospective comparative randomised study was carried out from 2008 to 2009, including two groups of 30 patients who underwent THA for primary osteoarthritis. One surgeon performed all the surgical procedures using a minimally invasive direct anterior approach. In one group, the planning was made on calibrated X-rays using 2D templates. In the other group, a CT-scan based 3D computerised planning was performed with dedicated software. The reconstructed hip final anatomy was compared postoperatively to the preoperative planning and the accuracy was expressed as the mean difference (±SD) between the planned positioning and the final positioning of the implants. RESULTS The prediction rate for the stem and the cup sizes were respectively of 100% and 96% in the 3D group versus 43% for both components in the 2D group. When combining both components, the prediction rate was 96% in the 3D group versus 16% in the 2D group. In the 3D group, a high accuracy was achieved for the planning of the leg length (-1.8±3.6 mm ranging from -8 to+4mm) and the femoral offset (-0.07±2.7 mm ranging from -5 to+4mm) versus 1.37±6.4mm ranging from -9 to 13 mm and 0.33±5.7 mm (-16 to 11 mm) in the 2D templating group (P<0.0001). DISCUSSION The 3D planning gives a higher accuracy than conventional 2D templating in forecasting the size of cup and the stem. This contributes to the prediction for leg length and offset that is more reliable with the 3D technique. This study suggests that 3D planning CT-scan data is an attractive alternative to navigation to restore these parameters. The high accuracy achieved by a low-experience surgeon suggests that 3D planning may help shorten the learning curve when using the minimally invasive direct anterior approach. LEVEL OF EVIDENCE Level III low-powered prospective randomized trial.

Preoperative evaluation of the cervical spondylotic myelopathy with flexion-extension magnetic resonance imaging: about a prospective study of fifty patients.

Study Design. The authors evaluated preoperative modifications of the cervical spinal canal in flexion and extension in 50 patients with cervical spondylotic myelopathy (CSM) and looked for impingement of the spinal cord not diagnosed in the neutral position. Objective. To evaluate the usefulness of preoperative flexion-extension magnetic resonance imaging (MRI) for patients with CSM. Summary of Background Data. Dynamic factors contribute to CSM. Although the clinical manifestations and spinal or spinal cord morphology in patients with myelopathy have been reported, to our knowledge, there are no studies that include the cervical spinal cord length, sagittal diameter, and available space in patients with CSM in flexion, extension, and the neutral position. Methods. Dynamic MRI changes in canal stenosis during flexion-extension were evaluated in 50 patients with CSM in the supine position. The authors determined length of the cervical cord (LCC, C1-C7), cervical cord sagittal diameter (CCSD, C3-T1), cervical cord available space (CCAS, C3-T1), intramedullary high-intensity signal (IHIS) changes, number of stenosis, and severity of cord impingement in flexion, extension, and the neutral positions. Results. On both the anterior and posterior edges of the cord, mean LCC in flexion was longer than in extension or the neutral position and longer in the neutral position than in extension (P < 0.05). In all three positions, the average length of the anterior edge of the cervical cord was longer than the posterior edge (P < 0.05). The mean value of CCSD at each level in extension was greater than in flexion or the neutral position (P < 0.05). In the neutral position, CCSDs were greater than in flexion from C4 to C7 (P < 0.05), but this difference failed to reach significance at levels C3 and T1. In the neutral position, CCAS was greater than in either extension or flexion (P < 0.05), and CCAS was greater in flexion than in extension (P < 0.05) at all levels except C6, at which CCAS was greater in flexion than in either extension or the neutral position (P < 0.05). MRI demonstrated functional cord impingement (grade 3 of Mühle) in 6 of the 50 (12%) patients in flexion, in 17 patients (34%) in the neutral position, and in 37 patients (74%) in extension. IHIS was observed in flexion in 20 patients (40%), in the neutral position in 13 patients (26%), and in extension in 7 patients (14%). Conclusion. Cervical spondylotic myelopathy results from the synergistic action of static and dynamic factors, the latter of which play an important role. In some patients, IHIS on T2 images is only visible with the neck in flexion. That might explain why IHIS is first detected after surgery in some patients in whom MRI was obtained before surgery only in the neutral position. Dynamic MRI is useful to determine more accurately the number of levels where the spinal cord is compromised, and to better evaluate narrowing of the canal and IHIS. New information provided by flexion-extension MRI might change our strategy for CSM management.

Mathematical evaluation of jumping distance in total hip arthroplasty: influence of abduction angle, femoral head offset, and head diameter.

Background and purpose The jumping distance (JD) is the degree of lateral translation of the femoral head center required before dislocation occurs. The smaller the distance, the higher the theoretical risk of dislocation. The aim of our study was to evaluate this jumping distance and its variation according to the characteristics of the implant, and also the theoretical gain in using large head diameters of above 38 mm. Methods The JD was calculated as a function of the cup ante-version and abduction angles, the head diameter, and the head offset (defined as the distance between the center of the femoral head and the cup opening plane). Head diameters of 28, 32, 36, 40, 44 and 48 mm were analyzed. The abduction angle was increased from 0° to 80° with a 10° increment. The anteversion angle was increased from 0° to 40° with a 5° increment. Results The jumping distance was found to decrease as the cup abduction angle increased (0.25 mm each 1° for 32-mm head diameter). It increased by 0.05 mm for a 1° increase in the ante-version angle. The jumping distance increased as the head diameter increased (0.4 mm each mm diameter for a 45° abduction angle). The net gain obtained by increasing the diameter, however, decreased when abduction angle increased (0.25 each mm diameter for 60° abduction). The JD decreased by 0.92 mm for each 1-mm increase in head offset, showing that head offset was the most important parameter influencing the JD. Interpretation The theoretical gain in stability obtained by using a large femoral head (above 36 mm) is negligible in cases where there is a high cup abduction angle. An increase in offset of the femoral head substantially reduces the jumping distance and it should therefore be avoided.

Skeletal landmarks for TKR implantations: Evaluation of their accuracy using EOS imaging acquisition system

INTRODUCTION Lower extremity alignment remains one essential objective during total knee replacement. Implants positioning analysis requires selecting reliable skeletal landmarks. Our objective was to in vivo evaluate the precision of the implemented skeletal landmarks. This evaluation was based on multiple three-dimensional (3D) computer reconstructions of the lower extremity derived from an EOS biplanar low-dose X-ray system acquisition. A 3D angle measurement protocol was used. HYPOTHESIS Currently defined landmarks carry a tolerable uncertainty margin, which can still probably be further improved. MATERIAL AND METHODS Nine lower extremity 3D computer reconstructions were obtained from an EOS protocol based on seven simultaneous A-P and lateral views performed in standing position. A database was established by four operators; finally, building up a total of 99 in vivo 3D reconstructions of these nine lower extremities. Specific algorithms were used for such 3D reconstructions of lower extremities based on bone points and pre-identified contours on X-ray. Four femoral landmarks and four tibial landmarks were thus defined. For each bone and each landmark studied, a mean landmark for the 11 consecutive series elements was established. The deviation from each constructed landmark to the corresponding mean landmark was calculated based on the anteroposterior (x), longitudinal (y) and mediolateral axes (z), in translation (Tx, Ty, Tz) and in rotation (Rx, Ry, Rz). Uncertainty was estimated by the 95% confidence interval (95% CI). RESULTS The landmarks located at the middle of the segment joining the center of each posterior condyle and at the barycenter of the plateaux showed a greater reliability; these landmarks uncertainty (95% CI) of Tx, Ty, Tz was less than 1, 0.5, 1.5 mm for the femur and 1.5, 0.6, 0.6 mm for the tibia, respectively. The femoral landmarks using the center or posterior edge of the posterior condyles to define the mediolateral axis were retained; for rotations Rx, Ry, and Rz, uncertainty remained less than 0.3, 4, and 0.5 degrees. All of the tibial landmarks had a comparable reliability in rotation, 95% of the Rx and Rz deviations were under 0.5 and 1.3 degrees, respectively, with a mean error less than 1 degrees . For the tibial rotation Ry, the mean error was greater (4 degrees), with uncertainty (95% CI) at 11.2 degrees. All tibial translations showed a mean error of 1 mm. The 3D implantation angles were measured on two patients using preoperative 3D skeletal reconstructions and 3D geometric models of the implants repositioned on postoperative EOS knee X-rays. DISCUSSION The posterior condyles are rarely involved in the arthritic wear process, making them an anatomic landmark of choice in the analysis of the femoral component positioning. The femoral landmarks using the posterior condyles were sufficiently reliable for clinical use. However, the posterior contours of the tibial plateaux were less precise. The knees should be staggered from an anteroposterior perspective on the EOS lateral images so that they can be visualized separately. The anatomic zones on which the skeletal landmarks are based are usually removed by the bone cuts, making it preferable to save the preoperative computer reconstructions to analyze the postimplantation 3D reconstruction. CONCLUSION The lower extremity skeletal landmarks precision relates to the quality of the corresponding 3D reconstructions. Except for tibial rotation, all the translation and rotation parameters were estimated within a mean error margin inferior to 1.2 mm and 1.3 degrees, respectively. Making the reconstruction algorithms more robust would render certain anatomic zones even more precise. Biplanar low-dose EOS X-ray system is a tool of the future to generate 3D knee X-rays that can improve the evaluation and follow-up of total knee arthroplasty patients.

Outcome and serum ion determination up to 11 years after implantation of a cemented metal-on-metal hip prosthesis.

Background and purpose Little is known about the long-term outcome of cemented metal-on-metal hip arthroplasties. We evaluated a consecutive series of metal-on-metal polyethylene-backed cemented hip arthroplasties implanted in patients under 60 years of age. Methods 109 patients (134 joint replacements) were followed prospectively for mean 9 (7–11) years. The evaluation included clinical score, radiographic assessment, and blood sampling for ion level determination. Results At the final review, 12 hips had been revised, mainly because of aseptic loosening of the socket. Using revision for aseptic loosening as the endpoint, the survival rate at 9 years was 91% for the cup and 99% for the stem. In addition, 35 hips showed radiolucent lines at the bone-cement interface of the acetabulum and some were associated with osteolysis. The median serum cobalt and chromium levels were relatively constant over time, and were much higher than the detection level throughout the study period. The cobalt level was 1.5 μg/L 1 year after implantation, and 1.44 μg/L 9 years after implantation. Interpretation Revisions for aseptic loosening and radiographic findings in the sockets led us to halt metal-on-metal-backed polyethylene cemented hip arthroplasty procedures. If the rigidity of the cemented socket is a reason for loosening, excessive release of metal ions and particles may be involved. Further investigations are required to confirm this hypothesis and to determine whether subluxation, microseparation, and hypersensitivity also play a role.

Optimization of total hip arthroplasty implantation: is the anterior pelvic plane concept valid?

The anterior pelvic plane (APP) is currently used as superficial anatomical landmark for three-dimensional orientation during total hip arthroplasty (THA), specifically when using computer aided surgery. However, the actual parameter for characterizing the pelvic orientation is the sacral slope, which correlates with other functional spinal parameters. The goal of the paper was to investigate relationships between APP and sacral slope. Both were measured on 328 lateral radiographs of the pelvis in standing position by two observers. The poor correlation between APP and sacral slope suggest keeping using the reference to the APP for the per-operative orientation in the 3D space, while individually adjusting the preoperative planning to the sacral slope.

Clinical, radiological and histological evaluation of biphasic calcium phosphate bioceramic wedges filling medial high tibial valgisation osteotomies

We report clinical, radiological and histological findings following high tibial valgisation osteotomy (HTVO) using micro-macroporous biphasic calcium phosphate wedges fixed with a plate and locking screws. From 1999 to 2002, 43 knees were operated on and studied prospectively. All underwent clinical and radiological follow-up at days 1, 90, and 365 to evaluate consolidation and bone substitute interfaces. Additionally, biopsies were taken for histology at least 1 year after implantation from 10 patients who requested plate removal. Radiologically, consolidation was observed in 98% of cases. At 1 year, correction was unchanged in 95% of cases. Histological analysis revealed considerable MBCP resorption and bone ingrowth, both into the pores and replacing the bioceramic material. Polarised light microscopy confirmed normal bony architecture with trabecular and/or dense lamellar bone growth at the expense of the wedge implants. X-ray and micro-CT scan revealed a well organised and mineralised structure in the newly-formed bone. This study shows that using MBCP wedges in combination with orientable locking screws and a plate is a simple, safe and fast surgical technique for HTVO. The is the first study to examine the results by histological analysis, which confirmed good outcomes.

Iliac crest bone graft harvesting complications: A case of liver herniation

The iliac crest is an easily accessible donor site offering a relatively large and safe supply of bone. There are however possible complications; residual pain frequently, and more rarely herniation. This latters true incidence is unknown in a literature review, which found 15 articles. We report a case of liver herniation in a 64-year-old overweight lady after harvesting bone from her iliac crest. The clinical diagnosis was confirmed by CT scan. Despite an appropriate surgical repair, the hernia recurred. This serious complication of bone harvesting from the iliac crest, and possible other undesirable events described, prompted reconsideration of our harvesting techniques, and the use in our unit of bone substitutes or cell therapy to fill bone defects.

The EOS imaging system for understanding a patellofemoral disorder following THR.

An aspect of patellofemoral syndrome secondary to total hip replacement (THR) is mainly suggestive of a problem of femoral implant torsion. We here present the first reported case of patellofemoral syndrome secondary to THR relating to limb-length discrepancy, with no abnormality of femoral torsion. The pelvis adapted to the length inequality by axial rotation rather than frontal tilt, and this went undetected on standard X-ray and CT-scan. 3D imaging in upright posture on the EOS system enabled the situation to be clearly described and analyzed, and adapted surgical correction to be indicated.