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Dive into the research topics where Z. Apalla is active.

Publication


Featured researches published by Z. Apalla.


British Journal of Dermatology | 2012

Accuracy of dermoscopic criteria for the diagnosis of psoriasis, dermatitis, lichen planus and pityriasis rosea

A. Lallas; A. Kyrgidis; Thrasivoulos Tzellos; Z. Apalla; E. Karakyriou; A. Karatolias; Ioanna Lefaki; Eleni Sotiriou; D. Ioannides; Giuseppe Argenziano; Iris Zalaudek

Background  Dermoscopy is useful in evaluating skin tumours, but its applicability extends also to the field of inflammatory skin disorders. Plaque psoriasis (PP), dermatitis, lichen planus (LP) and pityriasis rosea (PR) are common inflammatory skin diseases, but little is currently known about their dermoscopic features.


Acta Dermato-venereologica | 2010

Photodynamic therapy for distal and lateral subungual toenail onychomycosis caused by Trichophyton rubrum: Preliminary results of a single-centre open trial.

Eleni Sotiriou; Thalia Koussidou-Ermonti; George Chaidemenos; Z. Apalla; D. Ioannides

. A combination of topical and systemic thera-pies seems to be the ideal approach in the treatment (1). However, as many patients have conditions that contra-indicate the administration of systemic anti-fungals, and as topical treatments alone are able to control cases of only mild to moderate severity, it is necessary to develop new safe and effective strategies for the treatment of onychomycosis. The use of photodynamic therapy (PDT) has ex-tended in many fields, including that of antimicrobial chemotherapy (1).


British Journal of Dermatology | 2010

Skin cancer: preventive photodynamic therapy in patients with face and scalp cancerization. A randomized placebo-controlled study.

Z. Apalla; Eleni Sotiriou; E. Chovarda; Ioanna Lefaki; D. Devliotou‐Panagiotidou; D. Ioannides

Background  Patients with a previous medical history of nonmelanoma skin cancers (NMSCs) often develop multiple or recurrent malignant lesions around the site of the primary tumour. This finding led to the field cancerization theory, which suggests that the entire epithelial surface of the regional skin has an increased risk for the development of malignant lesions. Management of field change is challenging, taking into account the high impact of NMSCs on public health and healthcare costs.


Journal of The European Academy of Dermatology and Venereology | 2009

Intraindividual, right–left comparison of topical 5-aminolevulinic acid photodynamic therapy vs. 5% imiquimod cream for actinic keratoses on the upper extremities

Eleni Sotiriou; Z. Apalla; F. Maliamani; N Zaparas; Despina Panagiotidou; D. Ioannides

Backround  Actinic keratoses (AKs) are considered as in situ squamous cell carcinoma. Early and effective treatment is important.


Journal of The European Academy of Dermatology and Venereology | 2010

Clinical and laboratory study of rosacea in northern Greece

Elizabeth Lazaridou; Z. Apalla; S Sotiraki; Nikolas G Ziakas; C Fotiadou; D. Ioannides

Background  Numerous factors have been implicated in the pathogenesis of rosacea, which remains obscure.


Journal of The European Academy of Dermatology and Venereology | 2013

Dermoscopy of early stage mycosis fungoides

A. Lallas; Z. Apalla; Ioanna Lefaki; Thrassivoulos Tzellos; Athanasios Karatolias; Eleni Sotiriou; Elizabeth Lazaridou; D. Ioannides; Iris Zalaudek; Giuseppe Argenziano

Background  Early stage mycosis fungoides (MF) is difficult to be clinically differentiated from chronic dermatitis (CD) in a high proportion of patients. Dermoscopy is a rapid, cheep, non‐invasive and widely used method for the evaluation of skin tumours and, recently, of inflammatory skin diseases, as well.


Journal of The European Academy of Dermatology and Venereology | 2014

Dermoscopic patterns of common facial inflammatory skin diseases

A. Lallas; Giuseppe Argenziano; Z. Apalla; Jean-Yves Gourhant; Pedro Zaballos; V. Di Lernia; Elvira Moscarella; Caterina Longo; Iris Zalaudek

Several common inflammatory dermatoses, such as rosacea, seborrheic dermatitis (SD), discoid lupus erythematosus (DLE) and granulomatous skin diseases manifest as erythematous macules or plaques on the facial skin. Although clinical examination represents the cornerstone of diagnosis, the broad variety of clinical features and uncommon presentations of these diseases may cause at times diagnostic and therapeutic uncertainty. Dermoscopy, in addition to its well‐documented value in evaluation of skin tumours, is continuously gaining appreciation also in the field of general dermatology.


British Journal of Dermatology | 2013

Dermoscopy of discoid lupus erythematosus

Aimilios Lallas; Z. Apalla; Ioanna Lefaki; Eleni Sotiriou; Elizabeth Lazaridou; D. Ioannides; Danica Tiodorovic-Zivkovic; Theodoros Sidiropoulos; D. Konstantinou; V. Di Lernia; Giuseppe Argenziano; Iris Zalaudek

Summary Background  Dermoscopy is useful in evaluating skin tumours, but its applicability also extends into the field of inflammatory skin disorders. Discoid lupus erythematosus (DLE) represents the most common subtype of cutaneous lupus erythematosus. While dermoscopy and videodermoscopy have been shown to aid the differentiation of scalp DLE from other causes of scarring alopecia, limited data exist concerning dermoscopic criteria of DLE in other locations, such as the face, trunk and extremities.


British Journal of Dermatology | 2008

Actinic cheilitis treated with one cycle of 5‐aminolaevulinic acid‐based photodynamic therapy: report of 10 cases

Eleni Sotiriou; Z. Apalla; T. Koussidou-Erremonti; D. Ioannides

neous inflammatory processes: an overview. Br J Dermatol 1983; 109 (Suppl. 25):89–98. 4 Cliff S, Bedlow AJ, Stanton AW, Mortimer PS. An in vivo study of the microlymphatics in psoriasis using fluorescence microlymphography. Br J Dermatol 1999; 140:61–6. 5 Ryan TJ. Microcirculation in psoriasis: blood vessels, lymphatics and tissue fluid. Pharmacol Ther 1980; 10:27–64. 6 Bacharach-Buhles M, El-Gammal S, Panz B, Altmeyer P. In psoriasis the epidermis, including the subepidermal vascular plexus, grows downwards into the dermis. Br J Dermatol 1997; 136:97–101. 7 Kahn HJ, Marks A. A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest 2002; 82:1255–7. 8 Kahn HJ, Bailey D, Marks A. Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi’s sarcoma and a subset of angiosarcomas. Mod Pathol 2002; 15:434–40. 9 Jackowski S, Janusch M, Fiedler E et al. Radiogenic lymphangiogenesis in the skin. Am J Pathol 2007; 171:338–48. 10 Staberg B, Klemp P, Aasted M et al. Lymphatic albumin clearance from psoriatic skin. J Am Acad Dermatol 1983; 9:857–61. 11 Davison SC, Ballsdon A, Allen MH, Barker JN. Early migration of cutaneous lymphocyte-associated antigen (CLA) positive T cells into evolving psoriatic plaques. Exp Dermatol 2001; 10:280–5. 12 Braun-Falco O, Christophers E. Structural aspects of initial psoriatic lesions. Arch Dermatol Forsch 1974; 251:95–110. 13 Braverman IM, Sibley J. Role of the microcirculation in the treatment and pathogenesis of psoriasis. J Invest Dermatol 1982; 78:12– 17. 14 Staberg B, Worm AM, Klemp P, Rossing N. Transvascular transport and distribution of fluid and protein in psoriasis. J Am Acad Dermatol 1983; 8:193–9.


Photodermatology, Photoimmunology and Photomedicine | 2011

The impact of different fluence rates on pain and clinical outcome in patients with actinic keratoses treated with photodynamic therapy.

Z. Apalla; Eleni Sotiriou; Despina Panagiotidou; Ioanna Lefaki; Christina Goussi; D. Ioannides

Background/purpose: Literature data suggest that lower fluence rates are preferable in terms of clinical response and tolerability for treating patients with actinic keratoses (AKs). We aimed to clarify the impact of different fluence rates on pain during photodynamic therapy (PDT) for AKs, as well as on treatment outcome.

Collaboration


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D. Ioannides

Aristotle University of Thessaloniki

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Eleni Sotiriou

Aristotle University of Thessaloniki

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A. Lallas

Aristotle University of Thessaloniki

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Elizabeth Lazaridou

Aristotle University of Thessaloniki

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Giuseppe Argenziano

Seconda Università degli Studi di Napoli

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Iris Zalaudek

Medical University of Graz

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Elena Sotiriou

Aristotle University of Thessaloniki

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Elvira Moscarella

University of Modena and Reggio Emilia

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Aikaterini Patsatsi

Aristotle University of Thessaloniki

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Athanassios Kyrgidis

Aristotle University of Thessaloniki

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