Z. Leibovitz

Prediction of microcephaly at birth using three reference ranges for fetal head circumference: can we improve prenatal diagnosis?

To evaluate the prediction of microcephaly at birth (micB) using established and two new reference ranges for fetal head circumference (HC) and to assess whether integrating additional parameters can improve prediction.

Microcephaly at birth ‐ the accuracy of three references for fetal head circumference. How can we improve prediction?

To evaluate the prediction of microcephaly at birth (micB) using established and two new reference ranges for fetal head circumference (HC) and to assess whether integrating additional parameters can improve prediction.

Assessment of fetal midbrain and hindbrain in mid‐sagittal cranial plane by three‐dimensional multiplanar sonography. Part 1: comparison of new and established nomograms

To construct nomograms for fetal midbrain (MB) and hindbrain (HB) dimensions, assessed in the mid‐sagittal cranial plane by three‐dimensional multiplanar sonographic reconstruction (3D‐MPR).

Assessment of fetal midbrain and hindbrain in mid‐sagittal cranial plane by three‐dimensional multiplanar sonography. Part 2: application of nomograms to fetuses with posterior fossa malformations

To apply fetal midbrain (MB) and hindbrain (HB) nomograms, developed using three‐dimensional multiplanar sonographic reconstruction (3D‐MPR) in the mid‐sagittal cranial plane, to fetuses with known posterior fossa malformations.

The fourth ventricle index – a sonographic marker for severe fetal vermian dysgenesis / agenesis

Prenatal diagnosis of midbrain‐hindbrain (MB‐HB) malformations relies primarily on abnormal size and shape of the cerebellum and retrocerebellar space, particularly ‘open fourth ventricle’ (4V), the most common indicator of MB‐HB malformations. The aim of this study was to present the fourth ventricle index (4VI), and to evaluate its role as a marker for severe vermian dysgenesis/agenesis in cases without open 4V.

Fetal posterior fossa dimensions: normal and anomalous development assessed in mid‐sagittal cranial plane by three‐dimensional multiplanar sonography

To construct nomograms of the dimensions of the fetal posterior fossa (PF), assessed in the mid‐sagittal plane in the second and third trimesters, and to assess how measurements from fetuses with PF abnormalities deviate from our normal ranges.

Sonographic imaging of fetal tympanic rings

To examine the feasibility of ultrasonographic imaging of fetal tympanic rings.

OC06.02: Prenatal diagnosis of brainstem anomalies: phenotypic spectrum and neuroimaging features

K.K. Haratz1,2, Z. Leibovitz1,3, P.S. Oliveira4, L. Gindes10,1, N. Raz1, L. Dafna1, M. Tamarkin1, Y. Shalev1,2, G. Malinger5,2, L. Schreiber6, D. Kidron7, A. Arad8, S. Egenburg8, D. Lev1,9, L. Ben-Sira11,2, A.F. Moron12, G. Kasprian13, D. Prayer14, F. Viñals15, A. Fink16, G. McGillivray17, R. Leventer18,19, C. Garel20, A. Poretti21,22, T. Lerman-Sagie23,1 1Fetal Neurology Unit, Ultrasound in Obstetric Gynecology Unit, Wolfson Medical Centre, Holon, Israel; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Department of Obstetrics and Gynecology, Bnai-Zion Medical Centre, Haifa, Israel; 4DDI – Federal University of São Paulo – UNIFESP, São Paulo, Brazil; 5Obstetric Gynecology Ultrasound Unit, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel; 6Department of Pathology, Wolfson Medical Centre, Holon, Israel; 7Pathology, Meir Medical Centre, Kfar Saba, Israel; 8Department of Pathology, Bnai-Zion Medical Centre, Haifa, Israel; 9Institute of Genetics, Wolfson Medical Centre, Holon, Israel; 10Obstetric Gynecology Ultrasound Unit, Wolfson Medical Centre, Ramat-Gan, Israel; 11Radiology, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel; 12Fetal Medicine Discipline, Department of Obstetrics, Federal University of São Paulo, São Paulo, Brazil; 13Medical University of Vienna, Vienna, Austria; 14Department of Radiology, Medical University of Vienna, Vienna, Austria; 15Clinica Sanatorio Aleman, Centro AGB Ultrasonografia, Concepcion, Chile; 16Medical Imaging, Royal Children’s Hospital, Melbourne, VIC, Australia; 17Murdoch Children’s Research Institute, Royal Women’s Hospital, Mercy Hospital for Women, Melbourne, VIC, Australia; 18Neurology, Royal Children’s Hospital, Murdoch Children’s Research Institute, Melbourne, VIC, Australia; 19Department of Pediatrics, University of Melbourne, Melbourne, VIC, Australia; 20Hôpital d’Enfants Armand-Trousseau, Paris, France; 21Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 22Department of Neurogenetics, Kennedy Krieger Institute, Baltimore, MD, USA; 23Pediatric Neurology Unit, Wolfson Medical Centre, Holon, Israel

Application of a novel prenatal vertical cranial biometric measurement can improve accuracy of microcephaly diagnosis in utero

To construct a reference range for a new vertical measurement of the fetal head and to assess whether its combination with fetal head circumference (HC) can prevent the misdiagnosis of microcephaly in fetuses with an acrocephalic‐like head deformation.

Application of a novel prenatal nomogram for vertical cranial biometry can improve accuracy of microcephaly diagnosis in utero

To construct a reference range for a new vertical measurement of the fetal head and to assess whether its combination with fetal head circumference (HC) can prevent the misdiagnosis of microcephaly in fetuses with an acrocephalic‐like head deformation.