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Dive into the research topics where Zacharoula Koukouli is active.

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Featured researches published by Zacharoula Koukouli.


Journal of Maternal-fetal & Neonatal Medicine | 2018

Predictive value of fetal scalp pH and base excess for fetal acidosis and poor neonatal outcome

Panagiotis Tsikouras; Zacharoula Koukouli; Barbara Niesigk; Bachar Manav; George Farmakides; Roland Csorba; Georgios Galazios; Alexander Tobias Teichmann

Abstract Objective: The objective of this study is to assess retrospectively the predictive value of fetal scalp pH and base excess (BE) for fetal acidosis and poor neonatal outcome in term, low-risk, spontaneous deliveries with suspicious or pathological intrapartum cardiotocography (CTG) tracings. Methods: Umbilical artery pH and BE values obtained immediately after delivery and Apgar score were the outcomes under consideration. Statistics included receiver-operating characteristic curve (ROC) and multiple logistic regression analysis. Results: Four hundred and six deliveries were included in the study. Scalp pH < 7.20 predicted umbilical pH ≤7.1 with 64.3% sensitivity and 92.9% specificity (p < .001). The corresponding positive-predictive value (PPV) was 24.3% and the negative-predictive value (NPV) was 98.6%. Scalp BE ≤ −7 mmol/l (a cut-off value provided by ROC curve analysis) predicted Apgar score ≤ 7 at 5 min with 61.9% sensitivity and 91.7% specificity (p < .001). The corresponding PPV and NPV were 29.5 and 97.7%, respectively. Neither scalp pH nor BE was significantly associated with umbilical BE values. Infants with intrapartum BE ≤ −7 mmol/l were 30 times on an average more likely to get a low Apgar score, independently of intrapartum pH values. Conclusion: Our study supports the consideration of both scalp pH and BE values, when fetal blood sampling (FBS) is used.


International Journal of Environmental Research and Public Health | 2018

Ten Years of Experience in Contraception Options for Teenagers in a Family Planning Center in Thrace and Review of the Literature

Panagiotis Tsikouras; Dorelia Deuteraiou; Anastasia Bothou; Xanthi Anthoulaki; Anna Chalkidou; Eleftherios Chatzimichael; Fotini Gaitatzi; Bachar Manav; Zacharoula Koukouli; Zervoudis S; Grigorios Trypsianis; George Galazios

Introduction: The goal of our study was to investigate and evaluate the contraceptive behavior in teenagers from our family planning centre that services two different religious and socioeconomic populations living in the Thrace area. Methods: During the last 10 years 115 Christian Orthodox (group A) and 53 Muslim teenagers (group B) were enrolled in our retrospective study. Contraceptive practice attitudes were assessed by a questionnaire. Religion, demographics, socio-economic characteristics were key factors used to discuss contraception and avoid unplanned pregnancy in each group and to compare with the contraceptive method used. Results: The most used contraceptive method—about two times more frequently—among Christian Orthodox participants was the oral contraceptive pill (p = 0.015; OR = 1.81, 95% CI = 1.13–2.90), while in the other group the use of condoms and IUDs was seven and three times more frequent, respectively. Our family planning centre was the main source of information for contraception. Conclusions: During adolescence, the existence of a family planning centre and participation in family planning programs plays a crucial role to help the teenagers to improve their knowledge and choose an effective contraception method.


Minimally Invasive Therapy & Allied Technologies | 2017

Ovarian reserve after fibroid embolization in premenopausal women

Panagiotis Tsikouras; Bachar Manav; Zacharoula Koukouli; Grigorios Trypsiannis; Georgios Galazios; Dimitrios Souftas; Vasileios Souftas

Abstract Objective: To investigate the effect of uterine artery embolization (UAE) for fibroids on ovarian pool of premenopausal women. Study design: Prospective case control study. Material and methods: One-hundred and twenty premenopausal women, aged between 40 and 50 years, who underwent UAE for symptomatic uterine fibroids and the same number of women, aged between 40 and 50 years, with symptomatic uterine fibroids, who were not offered treatment were recruited for this study. Hormonal status and ovarian reserve were evaluated by means of anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH) pre-procedural, three months, six months and 12 months after UAE. Results: No statistically significant decrease was noted in AMH values 12 months post procedure and no statistical significant alterations in AMH values between the two groups. Conclusions: Even though the study results may not be able to confirm the preservation of ovarian reserve and normal menstruation after UAE in premenopausal women, it should be considered as a friendly to normal menstruation treatment option of symptomatic fibroids.


The European Journal of Contraception & Reproductive Health Care | 2016

Contraceptive behaviour of Christian and Muslim teenagers at the time of abortion and post-abortion in Thrace, Greece.

Panagiotis Tsikouras; Zacharoula Koukouli; Nikolaos Psarros; Bachar Manav; Nikolaos Tsagias; Georgios Galazios

Abstract Objectives: The aims of the study were to compare the contraceptive behaviour of Christian and Muslim adolescents who had an abortion in Thrace, Greece, and to examine whether extensive contraceptive counselling at the time of abortion modified their subsequent contraceptive practices. Methods: Adolescents, aged 14–19 years, who had undergone an elective abortion in our department, were included in a prospective 12-year study. Extensive contraceptive counselling was offered before discharge from the hospital. Attitudes to contraception were assessed by means of a simple questionnaire at the time of abortion and at 1-year follow-up. Results: The study population comprised of 95 Christian Orthodox adolescents (Group A) and 79 Muslim adolescents (Group B). At the time of abortion, contraceptive behaviour differed significantly between the two groups (p = .004). Contraceptive methods used in Group A in comparison with Group B were as follows: oral contraceptives (27.4% vs. 12.7%), condoms (22.1% vs. 38.0%), interrupted coitus (18.9% vs. 20.3%), periodic abstinence (16.8% vs. 25.3%) and emergency contraception (14.7% vs. 3.8%). The commonest source of information on contraception in Group A was the gynaecologist (17.9%) and family planning clinic (15.8%), whereas in Group B it was the individual’s partner (25.3%) and parents (16.4%). Contraceptive behaviour was significantly modified in both groups at post-abortion follow-up (both p < .001). The original difference between the groups, however, persisted (p = .006). In Group A, oral contraceptives were the dominant method (48.4%), followed by condoms (30.5%), whereas in Group B, the order was still the reverse (24.1% and 46.8%, respectively). Conclusion: Cultural differences significantly affect the contraceptive behaviour. Nevertheless, interventions that promote contraception can still be successful in different populations.


Geburtshilfe Und Frauenheilkunde | 2016

Induction of Labor in Post-Term Nulliparous and Parous Women - Potential Advantages of Misoprostol over Dinoprostone.

Panagiotis Tsikouras; Zacharoula Koukouli; Bachar Manav; M. Soilemetzidis; A Liberis; Roland Csorba; Grigorios Trypsianis; Georgios Galazios


Archive | 2018

Causes of Visiting Teenagers in the Pediatric and Adolescence Examining Room

Panagiotis Tsikouras; Theodora-Eleftheria Deftereou; AnnaChalkidou; Xanthoula Anthoulaki; Anastasia Bothou; BacharManav; Zacharoula Koukouli; Stefanos Zervoudis; Iatrakis G; Georgios Galazios


Open Journal of Obstetrics and Gynecology | 2017

Physiopathological Mechanism and Assessment of Fetal Asphyxia

Panagiotis Tsikouras; Anastasia Bothou; Zacharoula Koukouli; Bachar Manav; Constantinos Bouschanetzis; Dorelia Deuteraiou; Xanthi Anthoulaki; Anna Chalkidou; Iatrakis G; Zervoudis S; George Galazios


Open Journal of Obstetrics and Gynecology | 2016

Late Αntepartum Ηemorrhage and Neonatal Outcome: A Retrospective Study

Panagiotis Tsikouras; Zacharoula Koukouli; A Liberis; Bachar Manav; Constantinos Bouschanetzis; Panagiotis Naoumis; Marina Dimitraki; Georgios Galazios


Geburtshilfe Und Frauenheilkunde | 2016

Twin pregnancy in a partial septate uterus and the contribution of Magnetic Resonance Imaging (MRI). A case report

P Naoumis; Zacharoula Koukouli; Bachar Manav; Panagiotis Tsikouras


Geburtshilfe Und Frauenheilkunde | 2016

Primary ovarian carcinoid tumors: Effective management of a rare and challenging condition

Zacharoula Koukouli; A Liberis; C Bouschanetsis; P Naoumis; Bachar Manav; N Psarros; Panagiotis Tsikouras

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Panagiotis Tsikouras

Democritus University of Thrace

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Bachar Manav

Democritus University of Thrace

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Georgios Galazios

Democritus University of Thrace

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A Liberis

Democritus University of Thrace

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Anna Chalkidou

Democritus University of Thrace

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Dorelia Deuteraiou

Democritus University of Thrace

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George Galazios

Democritus University of Thrace

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Grigorios Trypsianis

Democritus University of Thrace

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Iatrakis G

National and Kapodistrian University of Athens

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Zervoudis S

National and Kapodistrian University of Athens

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