Zafer Arslan

Tuberculin responses in children with allergic diseases.

Background: The prevalence of allergic disorders has been increasing over the last 30 years, especially in developed countries. One factor associated with this rise may be the decline of many childhood infections. We investigated tuberculin responses in allergic children in order to see the development of delayed‐type hypersensitivity reactions to tubercule bacillus infection.

Evaluation of allergic sensitization and gastroesophageal reflux disease in children with recurrent croup

Background:  Croup, which is seen commonly in childhood, is a disorder that can be recurrent and progress to bronchial asthma. In the present study the prevalence of gastroesophageal reflux (GER) and atopy and the response to therapy were investigated in children with recurrent croup.

Beta Laktam Antibiyotik Penisilin Allerjisi

Penisilin allerjisi oldugu dusunulerek Dr Sami Ulus Cocuk Hastanesi allerji bolumune refere edilen 30 cocuktan 2 14 yas arasi 7 erkek 8 kiz toplam 15 cocuk calismaya alindi Bu cocuklarda olayin dogrulugunu belirlemek ayrica test protokolunun emniyet ve etkinligini gormek icin hastalara sirasiyla penisilin major determinanti prepen ve penisilin G ile epidermal ve intradermal deri testleri penisilin G ile intramuskuler penisilin V ile oral provokasyon uygulandi nbsp; Ayrica penisilin yan zincir antijenik determinantlarinin protokoldeki onemini belirlemek icin amoksilinle de deri testleri ve oral provokasyon uygulandi Testler oncesi 10 hastanin da serumunda penisilin G ve V ile spesifik immunoglobulin E calisildi Sonucta sadece bir hastada prepen ile epidermal test esnasinda anafilaksi gelisti 6 6 olarak belirlenen bu pozitif reaksiyon disinda testlerin hicbir asamasinda pozitiflik gozlenmedi Sonuc olarak literaturde daha once bildirilmemis penisilin major determinanti prepen nin epidermal test esnasinda anafilaksiye neden olabilecegi gosterilirken penisilin allerjisi insidansinin dusuk oldugu vurgulanmistir Anahtar kelimeler: Penisilin Allerjisi Betalaktam Antibiyotik Tip 1 Anafilaksi