Zafer Özyildiz

Pleural mesothelioma in a nine-month-old Dog

This paper reports on an unusual case of pleural epitheloid mesothelioma in a nine-month-old male, mixed breed dog. The dog was presented in-extremis and, on post mortem examination, multiple, exophytic, frequently pedunculated, yellowish-red, soft to firm masses ranging from 3 mm to 6 cm in diameter were diffusely distributed over, and attached to, the pericardial and parietal pleural surfaces. Microscopically, these masses consisted of round to partially polygonalshaped, anaplastic cells with minimal cytoplasm and hyperchromatic nuclei covering papillomatous projections or as part of more densely cellular masses. A supporting fibrovascular stroma and mitotic figures were also evident. Constituent tumour cells were labeled positively with antibodies against both vimentin and cytokeratin. In contrast, the same cells exhibited equivocal labeling with an antibody directed against calretinin antigen and did not label with antibodies against carcinoembryonic antigen (CEA) and milk fat globule-related antigen (MFGRA). Such tumours are rare in dogs, particularly in such a young animal.

Histopathologic examination of the brain tissue in lambs with neurological symptoms: Enzootic ataxia

Bu calismada klinik anamnezinde sinirsel semptomlar gostererek olen kuzularin beyninde rastlanan patomorfolojik bulgularin retrospektif degerlendirilmesi amaclandi. Makroskobik olarak kortekste jelatinoz yumusamalar ve kavitasyonlar gozlendi. Beyin dokusu kesitlerine rutin hematoksilen eozin (HE) boya yontemi uygulandi. 6 olguda multifokal odaklar halinde gliozis dikkat cekti. Birisinde siddetli olmak uzere 4 olguda noronlarda kalsifikasyon, ayrica 4 olguda demiyelinizasyon ile bunlarin 3’unde gitter hucreleri mevcuttu. Farkli karakter ve siddetteki beyin lezyonlari histopatolojik olarak tespit edilerek; sinirsel semptomlar gostererek olen kuzulara enzootik ataksi tanisi konuldu.

Mast cell typing in aortic onchocerciasis and the immunohistochemicaldemonstration of Wolbachia bacteria

Rahşan YILMAZ*, Melek KOÇAK, Zafer ÖZYILDIZ, İsmail Şah HAREM Department of Pathology, Faculty of Veterinary Medicine, Harran University, Şanlıurfa, Turkey Department of Histology and Embryology, Faculty of Veterinary Medicine, Namık Kemal University, Tekirdağ, Turkey Department of Pathology, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, Burdur, Turkey Department of Histology and Embryology, Faculty of Veterinary Medicine, Harran University, Şanlıurfa, Turkey

A survey of feline neoplasms in Ankara from 1971 to 2005

In this study, cat tumor cases from the archives of Pathology Department of Veterinary Medicine Faculty of Ankara University that were encountered in the last 35 years from January 1971 to December 2005 were investigated. During this period 265 cases were received; 244 of these cases were obtained as biopsy while the rest 21 cases were from necropsy materials. Parameters regarding to age, sex, tumor localizations of the organs or body systems, origin, malignancy and the years encountered were indicated with Tables. Of the cases 131 were localized in the cutaneous system which is composed of skin and subcutaneus connective tissue. Seventy-five were female genital system tumors mostly localized in mammary glands. The rest were observed in alimentary, skeletal, hematopoietic, respiratory, and neuronal, endocrine, urinary systems as 22, 19, 8, 4, and 2, 2, 2 respectively. Tumors occurred in cats were compared due to type, localization, frequency and prevalence of the tumors and age, breed, sex of the cases. The data obtained were investigated and evaluated statistically.