Željko Kaštelan
University Hospital Centre Zagreb
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Publication
Featured researches published by Željko Kaštelan.
BioMed Research International | 2014
Trpimir Goluža; Alexander Boscanin; Jessica Cvetko; Viviana Kozina; Marin Kosović; Maja Marija Bernat; Miro Kasum; Željko Kaštelan; Davor Ježek
A number of studies have indicated that testicular macrophages play an important role in regulating steroidogenesis of Leydig cells and maintain homeostasis within the testis. The current paper deals with macrophages (CD68 positive cells) and Leydig cells in patients with nonobstructive azoospermia (NOA). Methods employed included histological analysis on semi- and ultrathin sections, immunohistochemistry, morphometry, and hormone analysis in the blood serum. Histological analysis pointed out certain structural changes of macrophages and Leydig cells in NOA group of patients when compared to controls. In the testis interstitium, an increased presence of CD68 positive cells has been noted. Leydig cells in NOA patients displayed a kind of a mosaic picture across the same bioptic sample: both normal and damaged Leydig cells with pronounced vacuolisation and various intensity of expression of testosterone have been observed. Stereological analysis indicated a significant increase in volume density of both CD68 positive and vacuolated Leydig cells and a positive correlation between the volume densities of these cell types. The continuous gonadotropin overstimulation of Leydig cells, together with a negative paracrine action of macrophages, could result in the damage of steroidogenesis and deficit of testosterone in situ.
Acta Clinica Croatica | 2011
Ivica Mokos; Željko Kaštelan; Nikolina Bašić-Jukić; Petar Kes; Josip Pasini
Bosnian Journal of Basic Medical Sciences | 2010
Nikolina Bašić-Jukić; Ljubica Bubić-Filipi; Drago Prgomet; Ana Djanić Hadzibegović; Mario Bilić; Lana Kovač; Željko Kaštelan; Josip Pasini; Ivica Mokos; Martina Bašić-Koretić; Petar Kes
Periodicum Biologorum | 2011
Tomislav Kulis; Darko Kolarić; Krešimir Karlović; Matej Knežević; Josip Samardžić; Milan Bitunjac; Svetlana Antonini; Željko Kaštelan
Acta Clinica Croatica | 2010
Tvrtko Hudolin; Željko Kaštelan; Eleonora Goluža; Nikolina Bašić-Jukić; Hrvoje Šošić
Journal of the Balkan Cities Association of Nephrology, Dialysis, Transplantation and Artificial Organs | 2011
Nikolina Bašić-Jukić; Vesna Furić-Čunko; Josip Pasini; Željko Kaštelan; Tvrtko Hudolin; Petar Kes
Medicina Fluminensis : Medicina Fluminensis | 2017
Dean Markić; Željko Kaštelan; Ahmad El-Saleh; Josip Španjol
Medicina : glasilo Hrvatskoga liječničkoga zbora, Podružnica Rijeka | 2017
Tomislav Kuliš; Luka Penezić; Ahmad El-Saleh; Dinko Hauptman; Nikola Knežević; Željko Kaštelan
Lijec̆nic̆ki vjesnik | 2017
Višnja Škerk; Goran Štimac; Ognjen Kraus; Jasmina Vraneš; Edita Sušić; Suzana Bukovski; Tvrtko Hudolin; Željko Kaštelan; Vesna Mađarić; Alemka Markotić; Suzana Mimica Matanović; Dragan Soldo; Dalibor Vukelić; Arjana Tambić Andrašević
Urologija II | 2016
Josip Španjol; Željko Kaštelan; Željko Fučkar