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Featured researches published by Zhang Guo-an.


Journal of Burn Care & Research | 2012

Epidemiology of 1974 burn patients at a major burn center in Beijing: a nine-year study.

Wang Cheng; Rong Yan-hua; Ning Fang-gang; Du Wei-li; Zhang Guo-an

To date, little epidemiological data are available on burns in China. This study describes the characteristics of burn patients admitted to a major burn center in Beijing to show trends in admission and outcomes in burned patients to share information about the current state of care for burned patients in our burn center. A retrospective study on 1974 burn patients admitted to Jishuitan Hospital in Beijing was conducted during the 9-year period from 2000 to 2008, and data were collected on age, gender, TBSA, etiology, length of hospital stay, mortality, and inhalation injury. The male:female ratio of the burn population was 2.41:1 and did not differ significantly over the study period (P > .05). The mean age of admission was 36 ± 16.3 years, and most patients were 30 to 39 years old (24.0%) or 20 to 29 years old (23.8%). The mean TBSA of burn was 14.7 ± 3.4%, ranging from 1 to 100%, and the mean size/age did not change significantly over the course of the study (P > .05). The incidence in burn injury decreased over the study period (P < .05). The most common cause of burn was flame (67.9%) followed by electrical (16.1%) and scald (9.5%). The mean length of hospital stay was 33.2 ± 3.5 days, extending from 1 to 413 days, and it did not differ significantly over the study period (P > .05). The mortality and inhalation injury rate were 2.8 and 6.9%, respectively. Annual mortality rate did not differ significantly over the study period (P > .05). This retrospective review of the specific epidemiological features of burn patients will provide important information for the development of proper control programs to reduce the incidence of burns and burn-related deaths.


Burns | 2015

Laryngeal morphologic changes and epidemiology in patients with inhalation injury: A retrospective study

Ning Fang-Gang; Chang Yang; Qiu Yu-Xuan; Rong Yan-hua; Du Wei-li; Wang Cheng; Wen Chun-Quan; Zhang Guo-an

BACKGROUND AND OBJECTIVES Laryngeal morphologic changes are important in risk assessment of upper airway obstruction (UAO) after inhalation injury. This retrospective study evaluates the clinical application of laryngeal burn classification system. MATERIALS AND METHODS Clinical data from January 1999 to June 2013 were analyzed retrospectively. The following data collected: age, gender, total burned surface area (TBSA), third-degree burn surface area, co-morbid injuries and complications, proportion of patients with tracheotomy, interval between tracheotomy and injury, incidence and mortality of UAO, and reasons for death. RESULTS Four hundred and forty-three patients were included; 405 patients underwent multiple fibro-laryngoscopic observation, of which I, II and III types of laryngeal burns were present in 49.9, 38.0, and 12.1% patients, respectively. Laryngeal burn severity was related to TBSA and third-degree burn surface area. Overall tracheotomy rate (n=443) was 37.02%. The mean interval between tracheotomy and injury was 10.0±12.17h. Over 75% patients underwent tracheotomy within 12h. Compared with moderate inhalation burn group, the severe inhalation burn group showed a significantly higher tracheotomy rate within 12h and a significantly shorter interval between tracheotomy and injury. Patient mortality was significantly related to the severity of inhalation injury. CONCLUSION The classification system of the morphologic laryngeal changes in laryngeal burn patients could effectively evaluate the UAO risk, enable earlier prophylactic tracheotomy after UAO onset, reduce surgical difficulties and risks, decrease clinical pressure of doctors, and prevent UAO. Laryngeal burn severity was related to TBSA and mortality and may be an important severity and prognosis indicator of inhalation injury.


African Journal of Biotechnology | 2011

The content and ratio of type I and III collagen in skin differ with age and injury

Wang Cheng; Rong Yan-hua; Ning Fang-gang; Zhang Guo-an


Burns | 2013

Circulational heat dissipation of upper airway: Canine model of inhalational thermal injury

Ran Zhao; Di La-na; Wen Chun-Quan; Ning Fang-gang; Zhang Guo-an


Burns | 2014

Pathological changes of the three clinical types of laryngeal burns based on a canine model

Wang Cheng; Zhao Ran; Liu Wei; Di La-na; Zhao Xiaozhuo; Rong Yan-hua; Ning Fang-gang; Zhang Guo-an


Archive | 2015

Method for preparing decellularized dermis material for skin grafting

Zhang Guo-an; Ning Fang-gang; Zhao Xiaozhuo


Archive | 2014

Improved process for preparing acellular dermal material for skin transplantation

Zhang Guo-an; Ning Fang-gang; Zhao Xiaozhuo


Chinese Journal of Nosocomiology | 2013

Effect of contaminated surgery on surgical environment of common purification system

Zhang Guo-an


Shandong Medical Journal | 2011

A study of repairing wound with tendon exposure with artificial dermis and autologous skin graft

Zhang Guo-an


Chinese Journal of Injury Repair and Wound Healing | 2010

Comprehensive treatment of forty-one patients with sternal osteomyelitis

Zhang Guo-an

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Ning Fang-gang

Beijing Jishuitan Hospital

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Rong Yan-hua

Beijing Jishuitan Hospital

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Wang Cheng

Beijing Jishuitan Hospital

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Zhao Xiaozhuo

Beijing Jishuitan Hospital

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Di La-na

Beijing Jishuitan Hospital

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Du Wei-li

Beijing Jishuitan Hospital

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Wen Chun-Quan

Beijing Jishuitan Hospital

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Chang Yang

Beijing Jishuitan Hospital

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Liu Wei

Fujian Medical University

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Ning Fang-Gang

Beijing Jishuitan Hospital

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