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Archive | 2011

Behandlungsansätze bei trockener AMD

Zohar Yehoshua; Philip J. Rosenfeld

Die altersabhangige Makuladegeneration (AMD) ist in den Industriestaaten der Hauptgrund irreversibler Erblindung bei Menschen uber 60 Jahren [1]. Schatzungsweise etwa 30% der Erwachsenen uber 75 Jahren weisen Zeichen einer AMD auf, von denen etwa 10% ein fortgeschrittenes oder spates Stadium der Erkrankung zeigen [2]. Die grose Mehrheit der AMD-Patienten haben die nicht-exsudative oder trockene Form der Erkrankung, charakterisiert durch eine Konstellation bestimmter klinischer Zeichen, einschlieslich Drusen, Pigmentanomalien (fokale Hyperoder Hypopigmentierungen des retinalen Pigmentepithels (RPE)) und geographischer Atrophie (GA) der Makula. Wie in der Age-Related Eye Disease Studie (AREDS) definiert, kann der Schweregrad der AMD in drei Kategorien eingeteilt werden: fruh, intermediar und fortgeschritten.


Investigative Ophthalmology & Visual Science | 2012

Correlation Between Choroidal Thickness At Baseline And Disease Progression In Eyes With Dry AMD: The COMPLETE Study

Raquel Goldhardt; Carlos Alexandre A. Garcia Filho; Zohar Yehoshua; Giovanni Gregori; William J. Feuer; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2017

Comparison between Spectral Domain and Swept Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization in Age-Related Macular Degeneration

Giovanni Gregori; Andrew R. Miller; Qinqin Zhang; Fang Zheng; Joao Rafael Dias; Zohar Yehoshua; William J. Feuer; Chieh-Li Chen; Sophie Kubach; Mary K. Durbin; Ruikang K. Wang; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2015

Reticular Pseudodrusen, Enlarging Geographic Atrophy, and Decreased Choroidal Thickness in Age-Related Macular Degeneration

Mariana Rossi Thorell; Raquel Goldhardt; Renata Portella Nunes; Carlos Alexandre de Amorim Garcia Filho; Giovanni Gregori; Zohar Yehoshua; William J. Feuer; Srinivas R. Sadda; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2015

Widefield Choroidal Thickness Maps in Dry Age Related Macular Degeneration with and without Reticular Pseudodrusen

Giovanni Gregori; Andrew Dominic Legarreta; Karen B Schaal; John E. Legarreta; Brian Evan Goldhagen; Emeline Radhika Ramenaden; Zohar Yehoshua; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2015

Association between growth of geographic atrophy (GA) and the complement factor I (CFI) Locus

Zohar Yehoshua; Carlos Alexandre A. Garcia Filho; Renata Portella Nunes; Giovanni Gregori; Fernando M. Penha; Andrew A. Moshfeghi; Kang Zhang; Srinivas R. Sadda; William J. Feuer; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2014

Widefield Choroidal Thickness Maps

Giovanni Gregori; Mariana Rossi Thorell; Zohar Yehoshua; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2013

Measuring drusen over time: OCT vs. Fundus Photography

Giovanni Gregori; Carlos Alexandre A. Garcia Filho; Zohar Yehoshua; Renata Portella Nunes; William J. Feuer; Srinivas R. Sadda; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2013

Progression of Geographic Atrophy Predicted by SD-OCT En Face Imaging of the Outer Retina

Renata Portella Nunes; Zohar Yehoshua; Andrew A. Moshfeghi; Giovanni Gregori; Paul F. Stetson; William J. Feuer; Philip J. Rosenfeld


Investigative Ophthalmology & Visual Science | 2012

Quantitative Changes of Retinal Pigment Epithelial Detachments Following Anti-VEGF Therapy using Spectral Domain Optical Coherence Tomography

Fernando M. Penha; Giovanni Gregori; Carlos Alexandre A. Garcia Filho; Zohar Yehoshua; William J. Feuer; Philip J. Rosenfeld

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Srinivas R. Sadda

University of Southern California

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Renata Portella Nunes

Federal University of São Paulo

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Andrew A. Moshfeghi

University of Southern California

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Fernando M. Penha

Bascom Palmer Eye Institute

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Raquel Goldhardt

Bascom Palmer Eye Institute

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