A. F. Sayed Ahmed

Synthesis of Some Uridine and Cytidine Derivatives

Some modified nucleosides were prepared from 5,6-disubstituted uridine, 5-substituted cytidine and cytidine by nucleophilic substitution reactions in alkaline or neutral medium; preliminary antibacterial activities of the synthesized compounds have been measured.

Addition–Cyclization Reactions of Cinnamoyl Isothiocyanate with Nitrogen and Oxygen Nucleophiles

The synthesis of pyrimidine, thiazine and pyridine derivatives utilizing cinnamoyl isothiocyanate is described.

Synthesis of Bicyclic Pyrimidine Nucleoside Derivatives

The reaction of 5-bromouridine and its 4-thio derivative with both nitrile sulfides and oxides is described.